Results 31 to 40 of about 54,975 (247)
Role of novel drug delivery systems in bioavailability enhancement: at a glance
, 2016 Novel drug delivery systems (NDDS) are one of the most strategies which enable to overcome the problems related to drug bioavailability. It is the rate and extent to which a drug becomes available to the target tissue after its administration.
Neha, Jain +3 more
core +2 more sources
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
, 2016 Nanoparticles (NPs) can be absorbed via M cells of Peyer’s patches after oral delivery leading to passive lymphatic targeting followed by systemic drug delivery. Hence, the study was aimed to formulate PLGA NPs of lopinavir.
Krutika Sawant (2887496) +2 more
core +1 more source
Advanced Engineering Materials, EarlyView.This study reports the development of antibacterial ceramic scaffolds derived from natural bovine bone. The bones were processed through sequential boiling and hydrogen peroxide treatment to remove organic matter, producing porous, mineral‐rich scaffolds.
Mohamad Hassan Taherian +6 more
wiley +1 more source
Redox-active antibiotics enhance phosphorus bioavailability
Science, 2021 Phenazines liberate phosphate Bacteria secrete a wide range of small molecules with chemical reactivity that offers multiple functions in different contexts. Phenazines are commonly considered to be antibiotics, but they can also participate in environmental redox reactions, especially with iron.
Darcy L. McRose, Dianne K. Newman
openaire +3 more sources
Advanced Functional Materials, EarlyView.Mucoadhesive amphiphilic block and statistical copolymers were synthesized via Reversible Addition–Fragmentation Chain Transfer polymerization from bio‐sourced myrcene and polyethylene glycol methacrylate. The resulting polymers exhibit narrow molar‐mass distributions, high regioselectivity, well‐defined microstructures, and tend to self‐assemble into ...
David Gintsburg +9 more
wiley +1 more source
Natural Biomaterials for Osteochondral Repair: From Source to Strategy
Advanced Healthcare Materials, EarlyView.Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu +5 more
wiley +1 more source
, 2011 Background : Olmesartan medoxomil (OLM), an anti-hypertensive agent administered orally has absolute bioavailability of only 26% due to the poor aqueous solubility (
Bindesh Vishnubhai Patel +5 more
core +1 more source