Results 1 to 10 of about 172,391 (263)

Formulation and Evaluation of Canagliflozin Self-nanomicellizing Solid Dispersion Based on Rebaudioside A for Dissolution and Solubility Improvement

Iraqi Journal of Pharmaceutical Sciences
Self-nanomicellizing solid dispersion is a new formulation that combines the advantages of solid dispersion and nanomicelles strategies to increase drug oral bioavailability.
Nizar Awish Jassem, Shaimaa Nazar Abd Alhammid   +1 more
doaj   +1 more source

Novel methotrexate long-acting system using ambroxol coating and hydroxypropyl methylcellulose encapsulation for preferential and enhanced lung cancer efficiency.

PLoS ONE
Methotrexate (MTX) is classified as an antimetabolite. It's commonly used to treat lung cancer. MTX is an immunosuppressant following the above-mentioned mechanism of action due to its poor selectivity.
Samaa Abdullah, Najla Altwaijry, Meaad Alnakhli, Ghezlan ALenezi, Alaa A Al-Masud, Hanan Henidi, Yahya F Jamous   +6 more
doaj   +1 more source

GAS HOLDUP AND AXIAL LIQUID DISPERSION IN THREE PHASE BUBBLE COLUMNS

Journal of Engineering and Sustainable Development, 2015
Axial liquid dispersion coefficient was studied in air-tap water systems (bubble columns) and air-tap water-PVC solid particles systems for different column diameters, 10, 15, and 30 cm, Each column had a gas distributor plate with perforated holes of
Burhan Sadeq Abdulrazzaq
doaj  

SOLID DISPERSION: ITS TYPES AND MECHANISM OF ENHANCEMENT OF SOLUBILITY BY SOLID DISPERSION

, 2019
ABSTRACT To improve dissolution of poorly water-soluble drugs and thus enhancing their bioavailability, the dispersion of one or more active pharmaceutical ingredient in a carrier at solid state is used. This process is known as solid dispersion. It has engrossed significant interest as an efficient means of improving the dissolution rate.
openaire   +2 more sources

The Impact of Polymers in Amorphous Solid Dispersion on the Bioavailability of Sulfonylureas and Meglitinides. [PDF]

Drug Des Devel Ther
Aulifa DL, Wibisono TTDW, Ningsih JD, Christy GDAB, Pertiwi DS, Praja HM, Gazzali AM, Amaliah S, Budiman A.   +8 more
europepmc   +1 more source

Thermoresponsive Solid Dispersion to Enhance Dissolution Profile of Atorvastatin Calcium: An Industrially Sustainable Alternative to Conventional Approaches. [PDF]

Pharmaceutics
Sherif AY, Ibrahim MA.
europepmc   +1 more source

Baicalein solid dispersion prepared by solvent evaporation enhances oral bioavailability and alleviates ulcerative colitis. [PDF]

Int J Pharm X
Wei X, Ji X, Li Z, Guo Z, Li Y, Jin Q.
europepmc   +1 more source

Development of Amorphous Solid Dispersion to Improve the Dissolution and Antiproliferative Activity of Brazilin. [PDF]

Drug Des Devel Ther
Tristiyanti D, Sriwidodo S, Hamdani S, Daruwati I, Budiman A.   +4 more
europepmc   +1 more source

Amorphous Solid Dispersion Hydrogel Platform for Transdermal Delivery of Cannabidiol with Therapeutic Potential for Dermatitis. [PDF]

Pharmaceutics
Chuluunbaatar BA, Jeong Y, Ok J, Song Y, Son JW, Kang JH, Lee W, Min KH.   +7 more
europepmc   +1 more source

Solid dispersion of BIBR1532: A potent therapeutic for oesophageal squamous cancer. [PDF]

World J Gastrointest Oncol
Zhang XJ, Deng NX, Zhang HQ, Cen JZ, Zheng ZX, Guo MQ, Huang ZW.   +6 more
europepmc   +1 more source