Results 1 to 10 of about 22,095 (155)
Surface Solid Dispersion and Solid Dispersion of Meloxicam: Comparison and Product Development [PDF]
Advanced Pharmaceutical Bulletin, 2017 Purpose: A comparative study was carried out between surface solid dispersion (SSD) and solid dispersion (SD) of meloxicam (MLX) to assess the solubility and dissolution enhancement approach and thereafter develop as patient friendly orodispersible tablet.
Mayank Chaturvedi +4 more
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Journal of Pharmacy And Bioallied Sciences, 2012 The present study was aimed to increase the solubility of the poorly water soluble drug Telmisartan by using Surface solid dispersion (SSD) made of polymers like Poloxamer 407, PEG 6000 by Solvent evaporation method. The drug was solubilized by surfactants and/or polymers then adsorbed onto the surface of extremely fine carriers to increase its surface
Bhumika Patel +2 more
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Journal for Research in Applied Sciences and Biotechnology, 2023 The majority of patients prefer to take their medications orally. However, many drugs' limited usage in oral administration is a result of their poor solubility. One important element that influences the rate of dissolution and bioavailability is solubility.
Sharanpreet Kaur +3 more
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SOLID DISPERSION: ITS TYPES AND MECHANISM OF ENHANCEMENT OF SOLUBILITY BY SOLID DISPERSION
, 2019 ABSTRACT To improve dissolution of poorly water-soluble drugs and thus enhancing their bioavailability, the dispersion of one or more active pharmaceutical ingredient in a carrier at solid state is used. This process is known as solid dispersion. It has engrossed significant interest as an efficient means of improving the dissolution rate.
Beena Kumari 1 *, Harish Kumar Bishnoi 2
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Exciton dispersion in molecular solids
Journal of Physics: Condensed Matter, 2015 The investigation of the exciton dispersion (i.e. the exciton energy dependence as a function of the momentum carried by the electron-hole pair) is a powerful approach to identify the exciton character, ranging from the strongly localised Frenkel to the delocalised Wannier-Mott limiting cases.
Cudazzo P. +3 more
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An investigation on the solid dispersions of chlordiazepoxide
International Journal of Biomedical Science, 2007 The aim of this study was to prepare solid dispersions of chlordiazepoxide techniques to improve its dissolution rate. To this end, three techniques namely, two solvent methods and co-grinding technique were used. Solid dispersions of chlordiazepoxide in polyvinylpyrrolidone (PVP), Eudragit E100, Mannitol and Sorbitol with two different ratios of drug ...
Ali, Nokhodchi +3 more
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Characterization of olanzapine-solid dispersions.
Iranian journal of pharmaceutical research : IJPR, 2011 To enhance the aqueous solubility of olanzapine by using the Solid dispersion technique. Solid dispersions of olanzapine were prepared by the dispersion method using using PGS and SSG as carriers. Drug-carrier ratios such as 1 : 1, 1 : 2, 1 : 4, 1 : 6, 1: 8 and 1 : 10 were tried for optimization.
Krishnamoorthy, Venkateskumar +5 more
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Formulation of solid dispersion and surface solid dispersion of nifedipine: A comparative study
African Journal of Pharmacy and Pharmacology, 2013 In this study, an attempt was taken to enhance the solubility and dissolution characteristics of nifedipine, a poorly water soluble calcium channel blocking agent, by preparing solid dispersions (SD) with water soluble carriers; Poloxamer 407, HPMC 5 cPs, polyethylene glycol (PEG) 4000 and 6000 and surface solid dispersions (SSD) with insoluble ...
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Journal of Current Pharma Research, 2010 Solid dispersions have attracted considerable interest as an efficient means of improving the dissolution rate and hence the bioavailability of a range of hydrophobic drugs. This article reviews the various preparation techniques for solid dispersion and compiles some of the recent technology transfers. The different types of solid dispersions based on
A.Arunachalam . +5 more
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