Results 41 to 50 of about 22,095 (155)

Co-Amorphous Solid Dispersion System for Improvement in Dissolution Profile of N-(((1r,4r)-4-((6-fluorobenzo[d]oxazol-2-yl)amino)cyclohexyl)methyl)-2-methylpropane-2-sulfonamide as a Neuropeptide Y5 Receptor Antagonist

open access: yesPharmaceutics
Background/Objectives: Brick dust molecules exhibit high melting points and ultralow solubility. Overcoming this solubility issue is challenging. Previously, we formulated a co-amorphous system for a neuropeptide Y5 receptor antagonist (NP) as a brick ...
Hironori Tanaka, Hiroshi Ueda
doaj   +1 more source

Methodology to analyse three dimensional droplet dispersion applicable to Icing Wind Tunnels [PDF]

open access: yes, 2009
This dissertation presents a methodology to simulate the dispersion of water droplets in the air flow typical of an Icing Tunnel. It is based on the understanding the physical parameters that influence the uniformity and the distribution of cloud of ...
Sorato, Sebastiano
core  

Preparation and characterization of celecoxib solid dispersions; comparison of poloxamer-188 and PVP-K30 as carriers [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2014
Objective(s):Solid dispersion formulation is the most promising strategy to improve oral bioavailability of poorly water soluble drugs. The aim of this study was to compare the effect of polyvinylpyrrolidone K30 (PVP) and poloxamer-188 (PLX) as carrier ...
Alireza Homayouni   +4 more
doaj  

Green Approach to Enhance Dissolution of Gliclazide: Thermoresponsive Solid Dispersion Based on Poloxamer 188/Propylene Glycol/Labrasol Ternary System

open access: yesPharmaceutics
Background/Objectives: Gliclazide’s limited water solubility restricts its absorption across the gastrointestinal tract and compromises its therapeutic performance.
Abdelrahman Y. Sherif   +1 more
doaj   +1 more source

Pentaerythritol as an excipient/solid-dispersion carrier for improved solubility and permeability of ursodeoxycholic acid [PDF]

open access: yes, 2018
In this study, the feasibility of using pentaerythritol as a novel excipient/solid-dispersion carrier for enhancing the biopharmaceutical properties of ursodeoxycholic acid (UA) is explored.
Milind Umekar   +5 more
core  

Anthelmintic efficacy of complex solid dispersion based on Fenbendazole and Niclozamide against dictyocaulosis and trichuriosis of sheep

open access: yesРоссийский паразитологический журнал
The purpose of the research is to study the anthelmintic efficacy of complex solid dispersion of fenbendazole and niclozamide against dictyocaulosis and trichuriosis of sheep.Materials and methods.
A. I. Varlamova   +5 more
doaj   +1 more source

Enhanced Supersaturation and Oral Absorption of Sirolimus Using an Amorphous Solid Dispersion Based on Eudragit® E

open access: yesMolecules, 2015
The present study aimed to investigate the effect of Eudragit® E/HCl (E-SD) on the degradation of sirolimus in simulated gastric fluid (pH 1.2) and to develop a new oral formulation of sirolimus using E-SD solid dispersions to enhance oral ...
Youngseok Cho   +5 more
doaj   +1 more source

Influence of dispersion aluminum powder on the burning rate of mixed solid fuel

open access: yesMATEC Web of Conferences, 2018
In work results of experimental study of influence dispersion of metal powder on burning rate in mixed solid fuel are provided. As metal fuel used additive of aluminum of different type depending on dispersion of powder.
Zolotorev Nikolay   +2 more
doaj   +1 more source

All-solid-state lithium secondary battery and production method for all-solid-state lithium secondary battery

open access: yes, 2021
An all-solid-state lithium secondary battery (1) comprising: an oxide solid electrolyte layer (11) including oxide solid electrolyte particles (11a) having lithium ion conductivity; a positive electrode active material layer (13) arranged on one surface ...
Jiaxiang Piao (13434111)   +2 more
core  

EFEK ULCEROGENIC DISPERSI PADAT IBUPROFEN-POLIVINILPIROLIDON (PVP) PADA TIKUS PUTIH JANTAN

open access: yesPharmaciana, 2013
Ibuprofen is an anti inflammatory, analgesic, and antipyretic agent. It has low solubility and bioavailability. The administration of ibuprofen in a long time and high dose can increased of side effect at gastrointestinal (peptic ulcer). This study was
Ririt Vita Febrianti , Iis Wahyuningsih
doaj   +1 more source

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