Results 51 to 60 of about 22,095 (155)
A review on solid dispersion: a modern formulation approach in drug delivery system
Journal of Applied Pharmaceutical Research, 2014 Drugs those are given as solid dosage form and having low solubility often have a lack of flexibility in drug formulation and administration. The dissolution rate could be the rate-limiting process in the absorption of a drug from a solid dosage form of ...
Dheeraj Kumar Gupta +4 more
doaj
, 2009 We report on the fabrication of a solid one-dimensional microstructured fiber with high nonlinearity and low dispersion at 1.55µm. A four-wave-mixing based tunable wavelength-conversion scheme was experimentally demonstrated in just 1.5m of this ...
Camerlingo, A. +7 more
core
Supersaturated Isotretinoin: Scrutiny into Solid States Attributes
PharmaceuticalsBackground/Objectives: The formulation development of Isotretinoin (ISN) is limited by its solubility and stability issues. This study aimed to characterise the BCS class II drug ISN, particularly the possible different solid state and formulate ...
Rana Sejare +4 more
doaj +1 more source
Indonesian Journal of Chemical Research, 2023 Acetosal is classified in the Biopharmaceutical Classification System (BCS) class II (low solubility, high permeability). Low solubility causes a decreased dissolution rate. Polyvinyl pyrrolidone (PVP) K-30 is an inert carrier easily soluble in water and
Khuswatun Khasanah +2 more
doaj
Brazilian Journal of Pharmaceutical Sciences, 2020 The aim of the present study was to enhance the dissolution rate of an NSAID drug Ketoprofen by formulating it into solid dispersions with water soluble carrier Poloxamer 188 and Eudragit S 100. The solid dispersions of Ketoprofen with Poloxamer 188 were
Ravi Yashwant Savardekar +1 more
doaj +1 more source
New binary solid dispersion of indomethacin and croscarmellose sodium: physical characterization and in vitro dissolution enhancement [PDF]
, 2012 Solid dispersions (SDx) containing Indomethacin (IND), a poorly water-soluble drug, and the disintegrant excipient sodium croscarmellose (SC) were prepared by a co-drying method and characterized by Infrared spectroscopy (FT-IR), X-ray diffraction (XRD),
Ramírez Rigo, María Veronica +7 more
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CURRENT TRENDS IN SOLID DISPERSION: A REVIEW
, 2014 Poor bioavailability of the highly lipophilicdrugs is one major challenges being faced in pharmaceutical industry. Poor absorption of drug from the oral dosage form could be a result of low dissolution rate. Therefore many techniques have been introduced
Bhasin, Nirika
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IMPROVING SOLUBILITY OF METHOTREXATE BY SOLID DISPERSION
, 2023 Objective: Methotrexate (MTX) is a folate antimetabolite used for the management of neoplastic diseases like leukemia and breast cancer, Methotrexate is also used in the treatment of psoriasis as well as rheumatoid arthritis.
ASHOOR, JAMAL ALI +3 more
core
Pharmaceutics, 2018 Over the past decades, a large number of drugs as well as drug candidates with poor dissolution characteristics have been witnessed, which invokes great interest in enabling formulation of these active ingredients.
Xingwang Zhang +3 more
doaj +1 more source
Use of Solid Dispersion Systems in Pharmacy
Конденсированные среды и межфазные границы, 2020 An overview of the use of solid dispersion systems in pharmacy is presented. The main techniques of obtaining solid dispersions were considered. The simplest one is the solvent removal technique: the medicinal drug and the carrier are dissolved in the ...
Sof ’ya Yu. Silaeva +6 more
doaj +1 more source