Results 21 to 30 of about 22,095 (155)

Most promising solid dispersion technique of oral dispersible tablet

Beni-Suef University Journal of Basic and Applied Sciences, 2020
Background The most common problem about conventional dosage form is dysphagia (difficulty in swallowing). So, we design a new approach in a conventional dosage form which is oral dispersible tablet.
Vikrant K. Nikam, Shubham K. Shete, Jyoti P. Khapare   +2 more
doaj   +1 more source

Solid Dispersion Technology for Improving the Solubility of Antiviral Drugs

Pharmaceutical Sciences and Research, 2023
Most drugs, including antiviral drugs, show low solubility in water, which affects dissolution, bioavailability, and therapeutic effectiveness. Therefore, many antiviral drugs are given in very large doses.
Maria Elvina Tresia Butar-Butar, Nasrul Wathoni, Hestiary Ratih, Yoga Windhu Wardhana   +3 more
doaj   +1 more source

Dispersion controlled highly nonlinear fibers for all optical processing at telecoms wavelengths [PDF]

, 2010
We review our recent progress in the development of lead silicate glass fibers with high nonlinearity and tailored near-zero dispersion at telecommunication wavelengths, encompassing holey, all-solid microstructured and W-type fiber designs.
Shi, Jindan, Ponzo, Giorgio M., David J. Richardson, Horak, Peter, Richardson, David J., Xian Feng, Marco Petrovich, Francesca Parmigiani, Giorgio M. Ponzo, Camerlingo, Angela, Parmigiani, Francesca, Feng, Xian, Periklis Petropoulos, Angela Camerlingo, Jindan Shi, Petropoulos, Periklis, Peter Horak, Petrovich, Marco, Wei H. Loh, Poletti, Francesco, Loh, Wei H., Francesco Poletti   +21 more
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A novel and alternative approach to controlled release drug delivery system based on solid dispersion technique

Bulletin of Faculty of Pharmacy Cairo University, 2012
The solid dispersion method was originally used to improve the dissolution properties and the bioavailability of poorly water soluble drugs by dispersing them into water soluble carriers.
Tapan Kumar Giri, Kulesh Kumar, Amit Alexander, Ajazuddin, Hemant Badwaik, Dulal Krishna Tripathi   +5 more
doaj   +1 more source

Sustained-Release Solid Dispersion of High-Melting-Point and Insoluble Resveratrol Prepared through Hot Melt Extrusion to Improve Its Solubility and Bioavailability

Molecules, 2021
This study aimed to prepare a sustained-release solid dispersion of poorly water-soluble resveratrol (RES) with high melting point in a single hot melt extrusion step.
Wenjing Zhu, Wenling Fan, Xiaotong Zhang, Meiqi Gao   +3 more
doaj   +1 more source

The Amorphous Solid Dispersion of Chrysin in Plasdone^® S630 Demonstrates Improved Oral Bioavailability and Antihyperlipidemic Performance in Rats

Pharmaceutics, 2023
Chrysin is a flavonoid with various biological activities. However, its low water solubility and strong metabolism render its oral bioavailability rather poor.
Chenhui Wang, Xiaowei Liu, Ruihan Zhao, Meiqing Yang, Wenqian Liu, Qiuyang Dai, Xiaofeng Bao, Yong Chen, Jun Ma   +8 more
doaj   +1 more source

DEVELOPMENT OF SUSTAINED RELEASE TABLETS CONTAINING SOLID DISPERSIONS OF BACLOFEN [PDF]

Journal of Fundamental and Applied Sciences, 2013
Sustained release tablets containing solid dispersions granules of a poorly water soluble drug were prepared to investigate the controlled release of the drug.
K. H. Janardhana, R. Deveswaran, S. Bharath, B.V. Basavaraj, V. Madhavan   +4 more
doaj  

Composition and Technology Development for Obtaining Amorphous Solid Dispersion of Ebastine by Hot Melt Extrusion to Increase Dissolution Rate

Разработка и регистрация лекарственных средств, 2023
Introduction. Ebastine is a second-generation antihistamine drug available in the form of orally disintegrating tablets and film-coated tablets. Ebastine substance exhibits high bioavailability, but low solubility in water and gastrointestinal tract ...
K. A. Gusev, A. R. Aliev, Yu. E. Generalova, N. A. Aksenova, G. V. Rechkalov, D. N. Maimistov, G. M. Alekseeva, E. V. Flisyuk   +7 more
doaj   +1 more source

Experimental investigation and CFD simulation of liquid-solid-solid dispersion in a stirred reactor

, 2010
For understanding the monosodium aluminate hydrate crystallization from the supersaturated aluminate solution containing red mud as the leaching liquor of bauxite, the liquid-solid-solid dispersion of a simulant system, i.e.
Li, Xingang, Licheng Wang, Zhang, YF, Zhang, Yi, Xingang Li, Yi Zhang, Zhang, Yifei, Yifei Zhang, Wang, Licheng   +8 more
core   +1 more source

ENHANCEMENT OF DISSOLUTION AND ANALGESIC ACTIVITY OF CELECOXIB USING TERNARY SYSTEM [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2009
The purpose of the present study is to investigate the drugloaded solid dispersion system consisting of a drug, a carrier and asurfactant. Solid dispersions of a water insoluble drug celecoxib(CX) with PVP 40000, namely binary solid dispersion systems ...
Mohamed Amin
doaj   +1 more source