Results 11 to 20 of about 22,095 (155)
Drug Design, Development and Therapy, 2015 Eun-Sol Ha,1 Jeong-Soo Kim,2 In-hwan Baek,3 Jin-Wook Yoo,1 Yunjin Jung,1 Hyung Ryong Moon,1 Min-Soo Kim1 1College of Pharmacy, Pusan National University, 2Dong-A ST Co Ltd, Yongin, 3College of Pharmacy, Kyungsung University, Busan, South Korea Abstract:
Ha ES +6 more
doaj +1 more source
, 2017 The solubility issues complicating the delivery of the new drugs and also affect the delivery of many existing drugs. There are various techniques are available for enhancement of solubility. Solid dispersion is one of the most promising approaches for solubility enhancement.
M. E. Potkule*, A. D. Savkare, S. K. Sarode, P. S. Kalaskar
openaire +3 more sources
Indonesian Journal of Chemistry, 2023 Carvedilol (CVD) is a non-selective β-blocker. CVD is included in BCS class II. It has low water solubility. In this research, solid dispersion was used to increase the solubility and dissolution profile of CVD.
Iyan Sopyan +3 more
doaj +1 more source
Phytomedicine Plus, 2021 Background: Poorly water-soluble medicaments continue to be a challenging, however, significant class of herbal drugs for the management of an extensive range of ailments.
Shahid Ud Din Wani +6 more
doaj +1 more source
Preparation and Characterization of Carvedilol Solid Dispersion by Kneading Method
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2023 Solid dispersion using hydrophilic carrier is one of the approaches that has a potential to increase solubility, dissolution rate and consequently the oral bioavailability of poorly-water soluble drugs.
Ali Q. Hatem, Wedad K. Ali
doaj +1 more source
Formulation and evaluation of fast dissolving tablets of haloperidol solid dispersion
Saudi Pharmaceutical Journal, 2022 Purpose: The aim of this study was to design fast dissolving tablets (FDT) of the anti –psychiatric drug haloperidol in solid dispersion forms as a way to enhance its dissolution profile and anti-psychiatric effect.
Aya M. Eisa +2 more
doaj +1 more source
Current Trends on Solid Dispersions: Past, Present, and Future
Advances in Pharmacological and Pharmaceutical Sciences, 2022 Solid dispersions have achieved significant interest as an effective means of enhancing the dissolution rate and thus the bioavailability of a range of weakly water-soluble drugs.
Ruba Malkawi +3 more
doaj +1 more source
Asian Journal of Pharmaceutical Sciences, 2019 The objective of this study is to evaluate the feasibility of obtaining extended release of tacrolimus by a novel combination of lipid-based solid dispersion and matrix-type extended release tablet techniques.
Hui Xu +5 more
doaj +1 more source
ADMET and DMPK, 2023 Introduction: Olanzapine (OLZ) is a psychotropic class drug commonly used to treat schizophrenia, bipolar disorder, and acute manic episodes. It has less water solubility, resulting in a slow dissolution rate and oral bioavailability.
Leena Patil +5 more
doaj +1 more source
DEVELOPMENT OF SUSTAINED RELEASE TABLETS CONTAINING SOLID DISPERSIONS OF BACLOFEN
Journal of Fundamental and Applied Sciences, 2015 Sustained release tablets containing solid dispersions granules of a poorly water soluble drug were prepared to investigate the controlled release of the drug.
K. H. Janardhana +4 more
doaj +1 more source