Results 11 to 20 of about 784,608 (295)
Asian Journal of Pharmaceutical Sciences, 2015 Solid dispersion is one of the most promising strategies to improve oral bioavailability of poorly soluble API. However, there are inconsistent dissolution performances of solid dispersion reported which entails further investigation.
Siok-Yee Chan +4 more
doaj +3 more sources
Fundamental aspects of solid dispersion technology for poorly soluble drugs
Acta Pharmaceutica Sinica B, 2014 The solid dispersion has become an established solubilization technology for poorly water soluble drugs. Since a solid dispersion is basically a drug–polymer two-component system, the drug–polymer interaction is the determining factor in its design and ...
Yanbin Huang, Wei-Guo Dai
doaj +3 more sources
Asian Journal of Pharmaceutical Sciences, 2019 The objective of this study is to evaluate the feasibility of obtaining extended release of tacrolimus by a novel combination of lipid-based solid dispersion and matrix-type extended release tablet techniques.
Hui Xu +5 more
doaj +1 more source
Effect of dispersion interactions on the properties of LiF in condensed phases [PDF]
, 2014 Classical molecular dynamics simulations are performed on LiF in the framework of the polarizable ion model. The overlap-repulsion and polarization terms of the interaction potential are derived on a purely non empirical, first-principles basis.
Corradini, Dario +3 more
core +3 more sources
Solid Dispersion Technology for Improving the Solubility of Antiviral Drugs
Pharmaceutical Sciences and Research, 2023 Most drugs, including antiviral drugs, show low solubility in water, which affects dissolution, bioavailability, and therapeutic effectiveness. Therefore, many antiviral drugs are given in very large doses.
Maria Elvina Tresia Butar-Butar +3 more
doaj +1 more source
Field-cycle-resolved photoionization in solids [PDF]
, 2014 The Keldysh theory of photoionization in a solid dielectric is generalized to the case of arbitrarily short driving pulses of arbitrary pulse shape.
Zheltikov, A. M., Zhokhov, P. A.
core +3 more sources
DEVELOPMENT OF SUSTAINED RELEASE TABLETS CONTAINING SOLID DISPERSIONS OF BACLOFEN
Journal of Fundamental and Applied Sciences, 2015 Sustained release tablets containing solid dispersions granules of a poorly water soluble drug were prepared to investigate the controlled release of the drug.
K. H. Janardhana +4 more
doaj +1 more source
Most promising solid dispersion technique of oral dispersible tablet
Beni-Suef University Journal of Basic and Applied Sciences, 2020 Background The most common problem about conventional dosage form is dysphagia (difficulty in swallowing). So, we design a new approach in a conventional dosage form which is oral dispersible tablet.
Vikrant K. Nikam +2 more
doaj +1 more source
Solid lipid dispersion of calcitriol with enhanced dissolution and stability [PDF]
, 2011 Solid dispersion of calcitriol with lipophilic surfactants and triglycerides was developed by melt-mixing method to modify the release and enhance stability of the drug. The solid dispersions were characterized by differential scanning calorimetry (DSC),
Yuan, Ting +6 more
core +1 more source
Hydrodynamic and solid residence time distribution in a circulating fluidized bed: experimental and 3D computational study [PDF]
, 2008 Vertical profiles of local pressure, horizontal profiles of net vertical solid mass flux, and residence time distributions (RTD) of the solid phase are experimentally assessed in the riser of a small scale cold Circulating Fluidized Bed of 9 m high ...
Andreux, Régis +3 more
core +2 more sources