Results 11 to 20 of about 172,391 (263)
Surface Solid Dispersion and Solid Dispersion of Meloxicam: Comparison and Product Development [PDF]
Advanced Pharmaceutical Bulletin, 2017 Purpose: A comparative study was carried out between surface solid dispersion (SSD) and solid dispersion (SD) of meloxicam (MLX) to assess the solubility and dissolution enhancement approach and thereafter develop as patient friendly orodispersible ...
Mayank Chaturvedi +4 more
doaj +4 more sources
Green Approach to Enhance Dissolution of Gliclazide: Thermoresponsive Solid Dispersion Based on Poloxamer 188/Propylene Glycol/Labrasol Ternary System [PDF]
PharmaceuticsBackground/Objectives: Gliclazide’s limited water solubility restricts its absorption across the gastrointestinal tract and compromises its therapeutic performance.
Abdelrahman Y. Sherif +1 more
doaj +2 more sources
Solid Dispersion Characteristics of an Oscillatory Microfluidic Mixer: An Experimental and Numerical Investigation [PDF]
MicromachinesPoint-of-care (POC) diagnostic testing based on microfluidic technology plays an important role in coagulation management. Its precision is, however, limited by the inefficient mixing between blood and solid activators in laminar microfluidic flow.
Yao Lu, Haixuan Sun, Yifan Qin
doaj +2 more sources
Journal of Pharmacy and Bioallied Sciences, 2012 The present study was aimed to increase the solubility of the poorly water soluble drug Telmisartan by using Surface solid dispersion (SSD) made of polymers like Poloxamer 407, PEG 6000 by Solvent evaporation method.
Bhumika Patel +2 more
doaj +3 more sources
Fundamental aspects of solid dispersion technology for poorly soluble drugs
Acta Pharmaceutica Sinica B, 2014 The solid dispersion has become an established solubilization technology for poorly water soluble drugs. Since a solid dispersion is basically a drug–polymer two-component system, the drug–polymer interaction is the determining factor in its design and ...
Yanbin Huang, Wei-Guo Dai
doaj +3 more sources
Indonesian Journal of Chemistry, 2023 Carvedilol (CVD) is a non-selective β-blocker. CVD is included in BCS class II. It has low water solubility. In this research, solid dispersion was used to increase the solubility and dissolution profile of CVD.
Iyan Sopyan +3 more
doaj +1 more source
Phytomedicine Plus, 2021 Background: Poorly water-soluble medicaments continue to be a challenging, however, significant class of herbal drugs for the management of an extensive range of ailments.
Shahid Ud Din Wani +6 more
doaj +1 more source
Preparation and Characterization of Carvedilol Solid Dispersion by Kneading Method
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2023 Solid dispersion using hydrophilic carrier is one of the approaches that has a potential to increase solubility, dissolution rate and consequently the oral bioavailability of poorly-water soluble drugs.
Ali Q. Hatem, Wedad K. Ali
doaj +1 more source
Formulation and evaluation of fast dissolving tablets of haloperidol solid dispersion
Saudi Pharmaceutical Journal, 2022 Purpose: The aim of this study was to design fast dissolving tablets (FDT) of the anti –psychiatric drug haloperidol in solid dispersion forms as a way to enhance its dissolution profile and anti-psychiatric effect.
Aya M. Eisa +2 more
doaj +1 more source
Current Trends on Solid Dispersions: Past, Present, and Future
Advances in Pharmacological and Pharmaceutical Sciences, 2022 Solid dispersions have achieved significant interest as an effective means of enhancing the dissolution rate and thus the bioavailability of a range of weakly water-soluble drugs.
Ruba Malkawi +3 more
doaj +1 more source