Surface Solid Dispersion and Solid Dispersion of Meloxicam: Comparison and Product Development. [PDF]
Purpose: A comparative study was carried out between surface solid dispersion (SSD) and solid dispersion (SD) of meloxicam (MLX) to assess the solubility and dissolution enhancement approach and thereafter develop as patient friendly orodispersible tablet.
Chaturvedi M +4 more
europepmc +5 more sources
Abstract Aim The present study is to prepare and assess Irbesartan loaded surface solid dispersions (SSD) for enhancing the solubility and bioavailability of poor soluble drug. Method Irbesartan loaded SSD were prepared by co-evaporation method by using five different super disintegrants like crospovidone, croscarmellose sodium, potato starch ...
Madhusudhan Alle +2 more
exaly +2 more sources
Solubility and Dissolution Enhancement of Ebastine by Surface Solid Dispersion Technique
Ebastine (EBS) is a non-sedating antihistamine with a long duration of action. This drug has predominantly hydrophobic property causing a low solubility and low bioavailability. Surface solid dispersions (SSD) is an effective technique for improving the solubility and dissolution rate of poorly soluble drugs by using hydrophilic water insoluble ...
Lina S. Hussein, Eman B. H. Al-Khedairy
openaire +3 more sources
Solid lipid dispersion of calcitriol with enhanced dissolution and stability [PDF]
Solid dispersion of calcitriol with lipophilic surfactants and triglycerides was developed by melt-mixing method to modify the release and enhance stability of the drug. The solid dispersions were characterized by differential scanning calorimetry (DSC),
Yuan, Ting +6 more
core +1 more source
The present study was aimed to increase the solubility of the poorly water soluble drug Telmisartan by using Surface solid dispersion (SSD) made of polymers like Poloxamer 407, PEG 6000 by Solvent evaporation method. The drug was solubilized by surfactants and/or polymers then adsorbed onto the surface of extremely fine carriers to increase its surface
Bhumika Patel +2 more
openaire +3 more sources
From colloidal dispersions to colloidal pastesthrough solid–liquid separation processes [PDF]
Solid–liquid separation is an operation that starts with a dispersion of solid particles in a liquid and removes some of the liquid from the particles, producing a concentrated solid paste and a clean liquid phase.
Botet, Robert +6 more
core +6 more sources
Study of the oxygen electrode reaction using mixed conducting oxide surface layers. Part II: Small signal analysis [PDF]
The oxygen gas electrode has been studied for a number of mixed conducting oxide surface layers on top of Gd2Zr2O7 (TGZO) solid electrolytes. In part II of this paper we present the results of frequency dispersion measurements for the electrode reaction,
Burggraaf, A.J. +2 more
core +3 more sources
Ultrafast helicity control of surface currents in topological insulators with near-unity fidelity [PDF]
In recent years, a class of solid state materials, called three-dimensional topological insulators, has emerged. In the bulk, a topological insulator behaves like an ordinary insulator with a band gap.
Holleitner, Alexander W. +3 more
core +2 more sources
Study of the oxygen electrode reaction using mixed conducting oxide surface layers. Part I: Experimental methods and current-overvoltage experiments [PDF]
The oxygen gas electrode has been studied for a number of mixed conducting oxide surface layers on top of Gd2Zr2O7 (TGZO) solid electrolytes. In part II of this paper we present the results of frequency dispersion measurements for the electrode reaction,
Burggraaf, A.J. +2 more
core +3 more sources
Combination of (M)DSC and surface analysis to study the phase behaviour and drug distribution of ternary solid dispersions [PDF]
Purpose: Miscibility of the different compounds that make up a solid dispersion based formulation play a crucial role in the drug release profile and physical stability of the solid dispersion as it defines the phase behaviour of the dispersion.
A Paudel +31 more
core +2 more sources

