Results 11 to 20 of about 578,287 (295)

Solubility and Dissolution Enhancement of Lornoxicam by Surface Solid Dispersion

open access: yesIraqi Journal of Pharmaceutical Sciences
Lornoxicam (LOX) is (NSAID); it is a crystalline powder that ranges in color from orange to yellow and is practically insoluble in water. The aim of this study is to increase the solubility and dissolution of LOX using the surface solid dispersions SSD approach by employing hydrophilic-water insoluble carriers, such as Aerosil 200, Croscarmellose ...
Riyam Sadiq Jafer, Hanan Jalal Kassab
openaire   +3 more sources

Development and characterization of surface solid dispersion of curcumin for solubility enhancement

open access: yesJournal of Applied Pharmaceutical Research, 2014
Surface solid dispersion (SSD) of curcumin was developed and characterized with purview to overcome solubility hurdle in its pharmacokinetic and pharmacodynamic performance. SSDs were prepared by co-evaporation method using polyplasdone XL, croscarmelose sodium, and silicone dioxide and polyethlene glycol 6000 as carrier.
Singh, Mahendra Vikram   +4 more
openaire   +3 more sources

Enhancing therapeutic potential of poor aqueous soluble herbal drugs through solid dispersion-An overview

open access: yesPhytomedicine Plus, 2021
Background: Poorly water-soluble medicaments continue to be a challenging, however, significant class of herbal drugs for the management of an extensive range of ailments.
Shahid Ud Din Wani   +6 more
doaj   +1 more source

Development of olanzapine solid dispersion by spray drying technique using screening design for solubility enhancement

open access: yesADMET and DMPK, 2023
Introduction: Olanzapine (OLZ) is a psychotropic class drug commonly used to treat schizophrenia, bipolar disorder, and acute manic episodes. It has less water solubility, resulting in a slow dissolution rate and oral bioavailability.
Leena Patil   +5 more
doaj   +1 more source

Sustained-Release Solid Dispersion of High-Melting-Point and Insoluble Resveratrol Prepared through Hot Melt Extrusion to Improve Its Solubility and Bioavailability

open access: yesMolecules, 2021
This study aimed to prepare a sustained-release solid dispersion of poorly water-soluble resveratrol (RES) with high melting point in a single hot melt extrusion step.
Wenjing Zhu   +3 more
doaj   +1 more source

Wave Dispersion Behavior in Quasi-Solid State Concrete Hydration

open access: yesSensors, 2023
This paper aims to investigate wave dispersion behavior in the quasi-solid state of concrete to better understand microstructure hydration interactions. The quasi-solid state refers to the consistency of the mixture between the initial liquid–solid stage
Yin Chao Wu   +4 more
doaj   +1 more source

CFD simulation of gas-liquid floating particles mixing in an agitated vessel [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2017
Gas dispersion and floating particles suspension in an agitated vessel were studied numerically by using computational fluid dynamics (CFD). The Eulerian multi-fluid model along with standard k-ε turbulence model was used in the simulation.
Li Liangchao, Xu Bin
doaj   +1 more source

Bulk Flow Optimisation of Amorphous Solid Dispersion Excipient Powders through Surface Modification

open access: yesPharmaceutics, 2023
Particulate amorphous solid dispersions (ASDs) have been recognised for their potential to enhance the performance of various solid dose forms, especially oral bioavailability and macromolecule stability.
Danni Suhaidi   +4 more
doaj   +1 more source

Surface Dispersion Suppression in High-Frequency GaN Devices

open access: yesCrystals, 2022
GaN-based high electron mobility transistors (HEMTs) are shown to have excellent properties, showing themselves to perform well among the throng of solid-state power amplifiers.
Pengfei Zhu   +3 more
doaj   +1 more source

DEVELOPMENT OF SUSTAINED RELEASE TABLETS CONTAINING SOLID DISPERSIONS OF BACLOFEN

open access: yesJournal of Fundamental and Applied Sciences, 2015
Sustained release tablets containing solid dispersions granules of a poorly water soluble drug were prepared to investigate the controlled release of the drug.
K. H. Janardhana   +4 more
doaj   +1 more source

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