Results 41 to 50 of about 578,287 (295)

Dissolution Improvement of Simvastatin by Surface Solid Dispersion Technology

Dissolution Technologies, 2010
The objective of the present study was to formulate surface solid dispersions (SSD) of simvastatin to improve the aqueous solubility and dissolution rate to facilitate faster onset of action. Simvastatin is a BCS Class II drug having low solubility (1.45 µg/mL) and therefore low oral bioavailability (5%).
Monica Rao, Yogesh Mandage, Kaushik Thanki, Sucheta Bhise   +3 more
openaire   +1 more source

Surface melting of methane and methane film on magnesium oxide

, 2000
Experiments on surface melting of several organic materials have shown contradictory results. We study the Van der Waals interactions between interfaces in surface melting of the bulk CH_4 and interfacial melting of the CH_4 film on the MgO substrate ...
Ancilotto, Beaglehole, Bienfait, Bienfait, Bilalbegović, Chandavarkar, Chen, Chen, Chernov, Dal Corso, Dash, de Jeu, Djurišić, Dzyaloshinskii, Elbaum, Freitag, G. Bilalbegović, Hough, Martonchik, N. Klipa, Parsegian, Plomp, Pluis, Sabisky, van Pinxteren, Wilen, Wong   +26 more
core   +1 more source

The stellar structure and kinematics of dwarf spheroidal galaxies formed by tidal stirring [PDF]

, 2009
Using high-resolution N-body simulations we study the stellar properties of dwarf spheroidal galaxies resulting from the tidally induced morphological transformation of disky dwarfs on a cosmologically motivated eccentric orbit around the Milky Way ...
Callegari, Simone, Kazantzidis, Stelios, Klimentowski, Jaroslaw, Lokas, Ewa L., Mayer, Lucio   +4 more
core   +1 more source

Introduction of Side Chains into Polyglycine Dispersed on Solid Surface. I [PDF]

Bulletin of the Chemical Society of Japan, 1956
Abstract 1) Polyglycine dispersed on the surface of kaolinite was prepared by the polycondensation of N-carboxylic anhydride or glycine ester on kaolinite. 2) It was concluded that a part of glycyl residues in polyglycine dispersed on kaolinite was easily converted to seryl or threonyl residues by the ...
Shiro Akabori, Kenji Okawa, Mikio Sato
openaire   +1 more source

Surface-motility induction, attraction and hitchhiking between bacterial species promote dispersal on solid surfaces [PDF]

The ISME Journal, 2013
Abstract The ability to move on solid surfaces provides ecological advantages for bacteria, yet many bacterial species lack this trait. We found that Xanthomonas spp. overcome this limitation by making use of proficient motile bacteria in their vicinity. Using X. perforans and Paenibacillus vortex as models, we show that X.
Efrat, Hagai, Reut, Dvora, Tal, Havkin-Blank, Einat, Zelinger, Ziv, Porat, Stefan, Schulz, Yael, Helman   +6 more
openaire   +2 more sources

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Velocity dispersion due to anelasticity; implications for seismology and mantle composition [PDF]

, 1976
The concept of a relaxation spectrum is used to compute the absorption and dispersion of a linear anelastic solid. The Boltzmann after-effect equation is solved for a solid having a linear relationship between stress and strain and their first time ...
Anderson, Don L., Kanamori, Hiroo, Liu, Hsi-Ping   +2 more
core   +1 more source

Effect of preparation method on the surface properties and UV imaging of indomethacin solid dispersions [PDF]

European Journal of Pharmaceutics and Biopharmaceutics, 2019
This work explores the use of UV imaging in solid dispersion systems. Solid dispersions are one of the common strategies used in improving the dissolution of poorly soluble drugs. Three manufacturing techniques (spray drying (SD), freeze drying (FD) and homogenising (HG)) are investigated.
Kofi Asare-Addo, Maen Alshafiee, Karl Walton, Adam Ward, Ana-Maria Totea, Sadaf Taheri, Nihad Mawla, Adeola O. Adebisi, Sheima Elawad, Chantel Diza, Peter Timmins, Barbara R. Conway   +11 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Dynamics of viscous amphiphilic films supported by elastic solid substrates

, 1997
The dynamics of amphiphilic films deposited on a solid surface is analyzed for the case when shear oscillations of the solid surface are excited. The two cases of surface- and bulk shear waves are studied with film exposed to gas or to a liquid.
B Kasemo, Bechhoefer J, Blinov L M, Croxton C A, de Gennes P-G, Duncan-Hewitt W C, Earnshaw J C, Evans E A, Fragneto G, Helfrich W, Ivkov V G, Kanazawa K K, Kosevich A M, Kosevich Yu A, Kragel J, Landau L D, Landau L D, M Jonson, M V Voinova, McDermott D C, Mitchell D J, Plesski V P, Sauerbrey G, Sillerud L O, Uberall H, Voinova M V, Voinova M V   +26 more
core   +2 more sources