Results 21 to 30 of about 96,110 (264)

Calculation bending deflection and stress for corrugated core sandwich panels employing equivalent stiffness method

Zhongguo Jianchuan Yanjiu, 2021
ObjectivesIn order to develop a computation method for the corrugated core panel bending issue and solve the bending deflection and stress of such panels, an equivalent stiffness method is proposed. MethodsFirst, the middle cores of these sandwich panels
Xiaoming WANG, Qiang WEI, Man PAN
doaj   +1 more source

The Impact of Pressure Angle and Tooth Root on the Modified Elliptical Gears Bending Stress and Fatigue Life

The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science
Noncircular gears are receiving growing attention due to their ability to deliver variable transmission ratios and to optimize motions in specialized mechanical and industrial applications.
Paul-Adrian PASCU, Laurentia ANDREI
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Casing Pass-through Capacity Analysis and Safety Evaluation for Ultra-deep Horizontal Wells

Shiyou jixie, 2022
In ultra-deep horizontal wells, when wellbore curvature is too large, casing will be unable to run or be damaged and even destroyed due to high bending stress.
Yang Weixing, He Yingzhuang, Tuo Yuheng, Zhang Qiang, Lian Zhanghua, Lu Feifei, Li Fei   +6 more
doaj  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

The Analysis of Stiffness and Driving Stability in Cross-Member Reinforcements Based on the Curvature of a Small SUV Rear Torsion Beam Suspension System

Applied Sciences, 2023
Most small SUVs in the automotive market are equipped with torsion beam suspension for the rear wheels. Torsion beam suspension consists of a cross-member and a trailing arm.
Keunuk Chung, Yeonghoon Lee, Jinwook Lee
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

The Validation and Discussion of a Comparative Method Based on Experiment to Determine the Effective Thickness of Composite Glass

Buildings
This study introduces and validates a comparative experiment-based method for determining the effective thickness of composite glass, including polymeric laminated glass (with polyvinyl butyral (PVB) and SentryGlas® (SGP) interlayers) and vacuum glazing.
Dake Cao, Xiaogen Liu, Zhe Yang, Jiawei Huang, Ming Xu, Detian Wan   +5 more
doaj   +1 more source

Experimental evaluation on railway axle ultrasonic testing (Effect of variable stress acting on the crack and axle bending stress during ultrasonic test)

Nihon Kikai Gakkai ronbunshu, 2017
The integrity of railway axles is a critical aspect for ensuring the safety of a railway system. Therefore, non-destructive inspections such as ultrasonic testing and magnetic particle testing are conducted periodically.
Masataka YAMAMOTO, Kazunari MAKINO, Hiromichi ISHIDUKA   +2 more
doaj   +1 more source