Results 31 to 40 of about 412,774 (311)

The Impact of Pressure Angle and Tooth Root on the Modified Elliptical Gears Bending Stress and Fatigue Life

The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science
Noncircular gears are receiving growing attention due to their ability to deliver variable transmission ratios and to optimize motions in specialized mechanical and industrial applications.
Paul-Adrian PASCU, Laurentia ANDREI
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Casing Pass-through Capacity Analysis and Safety Evaluation for Ultra-deep Horizontal Wells

Shiyou jixie, 2022
In ultra-deep horizontal wells, when wellbore curvature is too large, casing will be unable to run or be damaged and even destroyed due to high bending stress.
Yang Weixing, He Yingzhuang, Tuo Yuheng, Zhang Qiang, Lian Zhanghua, Lu Feifei, Li Fei   +6 more
doaj  

Deformation of face-centered cubic polycrystal and stress tensor components in grains [PDF]

, 2016
The transmission electron microscopy (TEM) has been used to indicate the contribution of stress tensorcomponents to internal stresses in deformed polycrystalline austenitic steel.
Gibert, Ivan, Kiseleva, Svetlana, Koneva, Nina, Popova, Natalya   +3 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

On stress resultant plasticity and viscoplasticity for metal plates [PDF]

, 2008
In this work we derive elastoplastic and elastoviscoplastic finite element formulations for stress resultant bending analysis of thin metal plates. The principle of maximum plastic dissipation is used to obtain the ingredients of the small strain stress ...
Brank, Boštjan, Dujc, Jaka
core   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, in collaboration with the Consensus Expert Panel (CEP) members, G. Alden Adkins, Brittany Adler, Hossein Ansari, Senada Arabelovic, Alan Baer, Denis Balaban, Shamik Bhattacharyya, Evelyn Bromet, Krishna Chaganti, Kamal Chemali, Melissa Cortez, Schartess Culpepper, Paul Dellaripa, Dana Direnzo, Daniel El Bogdadi, Robert Fearon, Mehrnez Fischbach, Judi Furlong, Christopher Gibbons, Rachael Gordon, Thomas Grader Beck, Syed Haider, Larry Hollenbeck, Chadwick R. Johr, Stuart S. Kassan, Brian King, Octavia Kincaid, Eugene Kissin, Vasileios Kyttaris, Lindsay Lally, Brandon M. Law, Janet Lewis, Scott M. Lieberman, Amanda Lusa, Joseph Lutt, Rashmi Maganti, Arthur M. Mandelin, Sara McCoy, Kerry Neall, Timothy Niewold, Anne Louise Oaklander, Ruben A. Peredo‐Wende, Lynn Petruzzi, Mark A. Porter, Guada Respicio Duque, Tania Reyna, Nathaniel M. Robbins, Elliot D. Rosenstein, Laura Rosow, Breanna Ruthrauff, Amit Sachdev, Nora Sandorfi, Sarah Schafer, Elena Schiopu, Chokkalingam Siva, Daniel Small, Sara M. Stern, Lauren Stiles, Susan Stoddard, Jinny Tavee, Donald Thomas, Edward L. Treadwell, Nagagopal Venna, Steven Vernino, Frederick B. Vivino, Brittany Weber, Sepideh Yadollahi, Huiying Yu, Scott Zashin   +88 more
wiley   +1 more source

The Validation and Discussion of a Comparative Method Based on Experiment to Determine the Effective Thickness of Composite Glass

Buildings
This study introduces and validates a comparative experiment-based method for determining the effective thickness of composite glass, including polymeric laminated glass (with polyvinyl butyral (PVB) and SentryGlas® (SGP) interlayers) and vacuum glazing.
Dake Cao, Xiaogen Liu, Zhe Yang, Jiawei Huang, Ming Xu, Detian Wan   +5 more
doaj   +1 more source

Experimental evaluation on railway axle ultrasonic testing (Effect of variable stress acting on the crack and axle bending stress during ultrasonic test)

Nihon Kikai Gakkai ronbunshu, 2017
The integrity of railway axles is a critical aspect for ensuring the safety of a railway system. Therefore, non-destructive inspections such as ultrasonic testing and magnetic particle testing are conducted periodically.
Masataka YAMAMOTO, Kazunari MAKINO, Hiromichi ISHIDUKA   +2 more
doaj   +1 more source