Results 51 to 60 of about 363,230 (254)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Benefit Sharing

, 2012
Research cannot be done by researchers alone. In most cases, additional resources are required, including human research participants, access to biodiversity for biological and genetic resources, or traditional knowledge. Benefit sharing has been part of global conventions and international ethics guidelines for over 25 years, predicated on the ...
openaire   +1 more source

Form follows function: in pursuit of solutions to the unresolved issues of the benefit-sharing regime for marine genetic resources under the BBNJ agreement

Frontiers in Marine Science
While the Agreement under the United Nations Convention on the Law of the Sea on the Conservation and Sustainable Use of Marine Biological Diversity of Areas Beyond National Jurisdiction (BBNJ Agreement) has pioneered the establishment of a benefit ...
Wenlong Yu, Yi Tang, Yuqiong Sun, Yanxuedan Zhang   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Perspectives of stakeholders on post-trial access arrangements in Ethiopia: a qualitative study

Global Bioethics
While there is limited practical experience and guidance on post-trial access (PTA) in clinical trials in low- and middle-income countries, the concept of benefit-sharing is firmly established in international ethical guidelines.
Gudina Terefe Tucho, Cynthia Khamala Wangamati, Diribe Makonene Kumsa, Rosemarie de la Cruz Bernabe   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Advancing Coffee Genetic Resource Conservation and Exchange: Global Perspectives and Strategies from the ICC 2024 Satellite Workshop

Proceedings
Climate change poses significant threats to coffee supply chains, highlighting the crucial role of coffee genetic resources in enhancing resilience and improving the livelihoods of coffee farmers.
Sarada Krishnan, Steffen Schwarz, Dirk W. Lachenmeier, Christophe Montagnon   +3 more
doaj   +1 more source

A Proposed “Agricultural Data Commons” in Support of Food Security

The African Journal of Information and Communication, 2019
This article identifies a data governance model that could help reduce dataset access inequities currently experienced by smallholder farmers in both developed-world and developing-world settings.
Jeremiah Baarbe , Meghan Blom, Jeremy De Beer   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Benefit-sharing as a global bioethical principle: A participating dialogue grounded on a Protestant perspective on fellowship

In die Skriflig, 2019
It has become evident from a practical, legal and theological perspectives that there are strong reasons that the principles underlying article 15 of the Universal Declaration of Bioethics and Human Rights (UDBHR) have to be grounded in the Bible.
Adriaan L. Rheeder
doaj   +1 more source