Results 71 to 80 of about 6,775,448 (288)

Global Standards, Corporate Diagrams and Indigenous Agency: ExxonMobil in Russia and Alaska

Arctic Review on Law and Politics, 2022
This paper examines how a transnational corporation (TNC) translates global standards and corporate policies into programs at sites of extraction.
Maria Tysiachniouk, Laura Henry, Leah S. Horowitz   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Form follows function: in pursuit of solutions to the unresolved issues of the benefit-sharing regime for marine genetic resources under the BBNJ agreement

Frontiers in Marine Science
While the Agreement under the United Nations Convention on the Law of the Sea on the Conservation and Sustainable Use of Marine Biological Diversity of Areas Beyond National Jurisdiction (BBNJ Agreement) has pioneered the establishment of a benefit ...
Wenlong Yu, Yi Tang, Yuqiong Sun, Yanxuedan Zhang   +3 more
doaj   +1 more source

Reflections on Intellectual Property Benefit-Sharing in Employment Situations in Ghana

The African Journal of Information and Communication, 2016
Among the key justifications for protecting intellectual property rights (IPRs) is that they incentivise and reward human creativity and innovation. The incentive/reward rationale is expected to foster a culture of innovation across jurisdictions and to ...
Poku Adusei
doaj   +1 more source

Compatible with Conviviality? Exploring African Ecotourism and Sport Hunting for Transformative Conservation

Conservation & Society, 2023
Recent decades have shown the increased popularity of market-based instruments (MBIs) for conservation despite mixed social and ecological outcomes.
Amos Ochieng, Niak Sian Koh, Stasja Koot
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Perspectives of stakeholders on post-trial access arrangements in Ethiopia: a qualitative study

Global Bioethics
While there is limited practical experience and guidance on post-trial access (PTA) in clinical trials in low- and middle-income countries, the concept of benefit-sharing is firmly established in international ethical guidelines.
Gudina Terefe Tucho, Cynthia Khamala Wangamati, Diribe Makonene Kumsa, Rosemarie de la Cruz Bernabe   +3 more
doaj   +1 more source

Access and Benefit Sharing on the Utilization of Plant Genetic Resources [PDF]

, 2018
Two International regimes that govern the access of plant genetic resources and sharing the benefit arising from their uses are the Nagoya Protocol of the United Nations Convention on Biological Diversity (CBD) and the International Treaty on Plant ...
MSc, M. S. (Muhammad)
core  

Implications of biological information digitization: Access and benefit sharing of plant genetic resources

Journal of World Intellectual Property, 2020
The decoupling of biological information from its material source has changed debates about global access and benefit sharing (ABS) of genetic resources.
S. Smyth, D. M. Macall, P. Phillips, J. Beer   +3 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source