Results 71 to 80 of about 332,234 (284)
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Implementing access and benefit sharing in eight countries [PDF]
Since 2012, national teams in eight countries in Asia, Africa and Latin America have been identifying options for policy, legal and administrative mechanisms for the implementation of the multilateral system of access and benefit sharing (MLS) for plant ...
Bessette, G. +6 more
core
Toward Global Justice through Benefit-Sharing [PDF]
Biopiracy" is a critical term coined to describe the practice of "bioprospecting," which falls short of today's ethical and legal standards. While bioprospecting is the age-old search for natural chemical products, biopiracy conjures up lurid images of ruthless perpetrators, ill-gotten riches, and plundered victims.
openaire +2 more sources
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Benefit and Cost Analysis of Resource Sharing
Libraries are not exempt from rising costs. The situation presented is how libraries can continue to provide services while also finding efficiencies in labor and operational expenditures.
Cherie Weible, Janelle Sander
doaj +1 more source
TRANSBOUNDARY WATER COOPERATION IN AFRICA: THE CASE OF THE NILE BASIN INITIATIVE (NBI) [PDF]
The aim of this paper is to identify the economic, social and political benefits of the transboundary cooperation by using the Nile Bain Initiative (NBI) as a case study. It also attempts to identify the obstacles that hinder transboundary cooperation in
Wondwosen TESHOME
core
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Property rights and benefit sharing: a case study of the Barotse floodplain of Zambia
The study sought to expose the underlying complexity of benefit sharing of ecosystem goods and services among multiple actors in the Barotse Floodplains of Zambia.
Machaya Jeff Chomba, Bimo Abraham Nkhata
doaj +1 more source

