Results 261 to 270 of about 2,274,656 (330)

Mammary Gland Microbiota in Benign Breast Diseases. [PDF]

open access: yesInt J Mol Sci
Ukraincev NI   +4 more
europepmc   +1 more source

NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex

open access: yesAdvanced Science, EarlyView.
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang   +8 more
wiley   +1 more source

Beyond Morphology: Quantitative MR Relaxometry in Pulmonary Lesion Classification. [PDF]

open access: yesCancers (Basel)
Graf M   +16 more
europepmc   +1 more source

AI‐Assisted Detection of Early Gastric Cancer via Visualization of Mucosal Acidity Compromise During Endoscopy

open access: yesAdvanced Science, EarlyView.
An AI‐assisted SERS system is developed to rapidly and reliably detect early gastric cancer by visualizing gastric mucosal acidity, enhancing endoscopic differentiation, improving guidance for submucosal dissection, and reducing false‐positive diagnoses.
Huihui Yan   +18 more
wiley   +1 more source

Spontaneous bruising finger

open access: yesJournal of the American College of Emergency Physicians Open
Cassandra Bradby
doaj   +1 more source

CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target

open access: yesAdvanced Science, EarlyView.
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo   +15 more
wiley   +1 more source

eIF4E Enriched Extracellular Vesicles Induce Immunosuppressive Macrophages through HMGCR‐Mediated Metabolic Rewiring

open access: yesAdvanced Science, EarlyView.
Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal   +15 more
wiley   +1 more source

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