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Malignant Mesothelioma [PDF]

open access: yesCancers, 2021
Malignant mesothelioma (MM) is a rare and aggressive cancer, related to chronic inflammation and oxidative stress caused mainly by exposure to asbestos [...]
Daniel L. Pouliquen, Joanna Kopecka
openaire   +3 more sources

A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk. [PDF]

open access: yes, 2020
BackgroundTumors comprise a complex microenvironment of interacting malignant and stromal cell types. Much of our understanding of the tumor microenvironment comes from in vitro studies isolating the interactions between malignant cells and a single ...
Azizi, Armon   +19 more
core   +4 more sources

LncRNA LTSCCAT promotes tongue squamous cell carcinoma metastasis via targeting the miR-103a-2-5p/SMYD3/TWIST1 axis

open access: yesCell Death and Disease, 2021
Abnormal expression of long-noncoding RNA is involved in the tumorigenesis and progression of various cancers, but the potential molecular regulatory mechanisms are unclear.
Mo Liu   +14 more
doaj   +1 more source

TCRP1 activated by mutant p53 promotes NSCLC proliferation via inhibiting FOXO3a

open access: yesOncogenesis, 2022
Previously, our lab explored that tongue cancer resistance-associated protein (TCRP1) plays a central role in cancer chemo-resistance and progression. Absolutely, TCRP1 was significantly increased in lung cancer. But the mechanism is far from elucidated.
Hao Liu   +8 more
doaj   +1 more source

Tumor-associated macrophages promote epithelial–mesenchymal transition and the cancer stem cell properties in triple-negative breast cancer through CCL2/AKT/β-catenin signaling

open access: yesCell Communication and Signaling, 2022
Background Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer with poor prognosis and limited treatment. As a major component of the tumor microenvironment, tumor-associated macrophages (TAMs) play an important role in ...
Xiangzhou Chen   +10 more
doaj   +1 more source

Can malignant and inflammatory pleural effusions in dogs be distinguished using computed tomography [PDF]

open access: yes, 2017
Computed tomography (CT) is the primary imaging modality used to investigate human patients with suspected malignant or inflammatory pleural effusion, but there is a lack of information about the clinical use of this test in dogs.
Aquino   +35 more
core   +1 more source

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models. [PDF]

open access: yes, 2015
Malignant melanoma requires precise resection in order to avoid metastatic recurrence. We report here that the telomerase-dependent, green fluorescent protein (GFP)-containing adenovirus OBP-401 could label malignant melanoma with GFP in situ in ...
Bouvet, Michael   +7 more
core   +1 more source

Mucoepidermoid carcinoma associated with osteosarcoma in a true malignant mixed tumor of the submandibular region [PDF]

open access: yes, 2015
True malignant mixed tumor, also known as carcinosarcoma, is a rare tumor of the salivary gland composed of both malignant epithelial and malignant mesenchymal elements.
Cerbelli, B   +4 more
core   +3 more sources

Targeting nicotinamide N-methyltransferase overcomes resistance to EGFR-TKI in non-small cell lung cancer cells

open access: yesCell Death Discovery, 2022
Activating mutations of epidermal growth factor receptor (EGFR) contributes to the progression of non-small cell lung cancer (NSCLC). EGFR tyrosine kinase inhibitor (TKI)-targeted therapy has become the standard treatment for NSCLC patients with EGFR ...
Jun Wang   +10 more
doaj   +1 more source

Clinical evaluation of endolymphatic radiotherapy in malignant lymphoma [PDF]

open access: yes, 1974
By endolymphatic injection of radioisotope 131I.Lipiodol, so.called endolymphatic radiotherapy, we treated 10 cases with malignant lymphoma and found a marked tumor reduction to normal size in all the 10 cases we tried.
Irino, Shozo   +3 more
core   +1 more source

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