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Korean Journal of Anesthesiology, 2012 Malignant hyperthermia (MH) is an uncommon, life-threatening pharmacogenetic disorder of the skeletal muscle. It presents as a hypermetabolic response in susceptible individuals to potent volatile anesthetics with/without depolarizing muscle relaxants ...
Dong-Chan Kim
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JAI (Jurnal Anestesiologi Indonesia)Malignant hyperthermia (MH) is a life-threatening clinical syndrome caused by hypermetabolism involving skeletal muscle. MH is very rare, but it is one of the causes of death in the operating room. MH is an autosomal dominant disease and can be triggered
Doni Fajri +2 more
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Malignant Hyperthermia in Slavonic cohort – clinical and genetic findings beyond standard diagnostics [PDF]
Orphanet Journal of Rare DiseasesBackground Malignant Hyperthermia (MH) is a rare, hereditary, life-threatening pharmacogenetic disorder. The genetic background of MH was identified only in approximately half of MH-susceptible (MHS) patients, differing between geographical areas ...
Martina Klincová +11 more
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Orphanet Journal of Rare Diseases, 2007 Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gases such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine ...
Pollock Neil +4 more
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Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2022 Malignant hyperthermia manifests as hypermetabolism of striated voluntary muscle. Generally, this condition occurs during general anesthesia when inhalational anesthetics and succinylcholine are used.
S. N. Ionov +2 more
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Humidity impacts volatile anesthetic and heat responses of malignant hyperthermia susceptible mice [PDF]
Skeletal MuscleBackground Malignant Hyperthermia (MH) is characterized by life-threatening whole-body hyperthermic reactions triggered by volatile anesthetics in susceptible individuals.
Miao He +9 more
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Malignant hyperthermia: patient undergoing limb debridement surgery—a case report [PDF]
Journal of Medical Case ReportsBackground Malignant hyperthermia is a rare but potentially fatal clinical emergency, primarily triggered by inhaled volatile anesthetics. It is associated with inherited autosomal-dominant skeletal muscle disorders and typically caused by mutations in ...
Zhixiang Geng +6 more
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Successful management of malignant hyperthermia without dantrolene: A case report [PDF]
Journal of International Medical ResearchMalignant hyperthermia during surgery represents a significant challenge for anesthesiologists due to its high mortality rate and the risk of long-term physiological damage.
Cailing Zhang +3 more
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Genetics of Malignant Hyperthermia
Scientific World Journal, The, 2006 Study of the genetics of the malignant hyperthermia syndrome began in families in which both malignant hyperthermia (MH) episodes had been experienced and individuals had strongly positive contracture tests diagnostic of susceptibility to MH.
Barbara W Brandom, Brandom Barbara W
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Keeping it in the family: malignant hyperthermia - how we predict, recognise and treat it [PDF]
Brazilian Journal of AnesthesiologyJonathan G. Bilmen, Pawan K. Gupta
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