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Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2022 Malignant hyperthermia manifests as hypermetabolism of striated voluntary muscle. Generally, this condition occurs during general anesthesia when inhalational anesthetics and succinylcholine are used.
S. N. Ionov +2 more
doaj +8 more sources
JAI (Jurnal Anestesiologi Indonesia)Malignant hyperthermia (MH) is a life-threatening clinical syndrome caused by hypermetabolism involving skeletal muscle. MH is very rare, but it is one of the causes of death in the operating room. MH is an autosomal dominant disease and can be triggered
Doni Fajri +2 more
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Korean Journal of Anesthesiology, 2012 Malignant hyperthermia (MH) is an uncommon, life-threatening pharmacogenetic disorder of the skeletal muscle. It presents as a hypermetabolic response in susceptible individuals to potent volatile anesthetics with/without depolarizing muscle relaxants ...
Dong-Chan Kim
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Malignant Hyperthermia in Slavonic cohort – clinical and genetic findings beyond standard diagnostics [PDF]
Orphanet Journal of Rare DiseasesBackground Malignant Hyperthermia (MH) is a rare, hereditary, life-threatening pharmacogenetic disorder. The genetic background of MH was identified only in approximately half of MH-susceptible (MHS) patients, differing between geographical areas ...
Martina Klincová +11 more
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RYR1 mutations linked to malignant hyperthermia susceptibility are associated with phenotypic changes in human B-lymphocytes [PDF]
Frontiers in ImmunologyRyanodine receptor 1 (RyR1) is a key intracellular Ca2+ release channel primarily expressed in skeletal muscle, but also in some immune cells.
Huiying Li +12 more
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Orphanet Journal of Rare Diseases, 2007 Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gases such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine ...
Pollock Neil +4 more
doaj +3 more sources
Malignant hyperthermia (literature review) [PDF]
Вестник анестезиологии и реаниматологии, 2023 The objective – to summarize the current literature data on the etiology, pathogenesis, diagnosis and treatment of malignant hyperthermia. The search and analysis of literature data on malignant hyperthermia in the medical information systems PubMed ...
R. R. Tukhvatullina, N. V. Matinyan
doaj +2 more sources
Humidity impacts volatile anesthetic and heat responses of malignant hyperthermia susceptible mice [PDF]
Skeletal MuscleBackground Malignant Hyperthermia (MH) is characterized by life-threatening whole-body hyperthermic reactions triggered by volatile anesthetics in susceptible individuals.
Miao He +9 more
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Malignant hyperthermia: patient undergoing limb debridement surgery—a case report [PDF]
Journal of Medical Case ReportsBackground Malignant hyperthermia is a rare but potentially fatal clinical emergency, primarily triggered by inhaled volatile anesthetics. It is associated with inherited autosomal-dominant skeletal muscle disorders and typically caused by mutations in ...
Zhixiang Geng +6 more
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Malignant hyperthermia?or not? [PDF]
Anaesthesia, 1985 Summary Some of the problems of diagnosis and management of malignant hyperthermia are discussed as illustrated by three case reports.
exaly +3 more sources