Results 11 to 20 of about 35,311 (176)

Keeping it in the family: malignant hyperthermia - how we predict, recognise and treat it [PDF]

Brazilian Journal of Anesthesiology
Jonathan G. Bilmen, Pawan K. Gupta
doaj   +2 more sources

Acute postoperative sepsis mimicking symptomology suspicious for malignant hyperthermia: case report [PDF]

Revista Brasileira de Anestesiologia, 2020
Background: Sepsis is a life-threatening organ dysfunction with non-specific clinical features that can mimic other clinical conditions with hyper metabolic state such as malignant hyperthermia.
Vendhan Ramanujam, Christopher R. Hoffman, Kevin Russo, Michael S. Green   +3 more
doaj   +5 more sources

Malignant Hyperthermia in PICU—From Diagnosis to Treatment in the Light of Up-to-Date Knowledge

Children, 2022
Malignant Hyperthermia (MH) is a rare, hereditary, life-threatening disease triggered by volatile anesthetics and succinylcholine. Rarely, MH can occur after non-pharmacological triggers too. MH was detected more often in children and young adults, which
Martina Klincová, Dagmar Štěpánková, Ivana Schröderová, Eva Klabusayová, Petr Štourač   +4 more
doaj   +1 more source

Profile of malignant hyperthermia susceptibility reports confirmed with muscular contracture test in Brazil [PDF]

Revista Brasileira de Anestesiologia, 2019
Background and objectives: Malignant hyperthermia is an autosomal dominant hypermetabolic pharmacogenetic syndrome, with a mortality rate of 10%–20%, which is triggered by the use of halogenated inhaled anesthetics or muscle relaxant succinylcholine. The
Helga Cristina Almeida da Silva, Gisele Ferreira, Gislene Rodrigues, Joilson Moura dos Santos, Pamela Vieira Andrade, Alexandre Hortense, Marcelo Vaz Perez, José Luiz Gomes do Amaral   +7 more
doaj   +5 more sources

Malignant hyperthermia [PDF]

Postgraduate Medical Journal, 1998
SummaryMalignant hyperthermia is a rare autosomal dominant trait that predisposes affected individuals to great danger when exposed to certain anaesthetic triggering agents (such as potent volatile anaesthetics and succinylcholine). A sudden hypermetabolic reaction in skeletal muscle leading to hyperthermia and massive rhabdomyolysis can occur.
R, Ben Abraham, P, Adnet, V, Glauber, A, Perel   +3 more
openaire   +4 more sources

Impact of a digital manual for guidance on malignant hyperthermia: patient education

Orphanet Journal of Rare Diseases, 2022
Background Malignant hyperthermia (MH) is a rare, hereditary disease with a hypermetabolic response to volatile anesthetics/succinylcholine. Susceptible patients face difficulties due to a lack of knowledge about MH.
Gislene Rodrigues, Pamela Vieira de Andrade, Joilson Moura dos Santos, José Luiz Gomes do Amaral, Helga Cristina Almeida da Silva   +4 more
doaj   +1 more source

Malignant hyperthermia: a case report with a literature review [PDF]

Archives of Aesthetic Plastic Surgery, 2022
Malignant hyperthermia is an extremely rare, potentially lethal disorder that occurs in susceptible patients who are exposed to triggering agents such as volatile anesthetic gases or depolarizing muscle relaxants. The clinical manifestations of malignant
Ji Hoon Kim, Chong Kun Lee, Chang Eun Chung, Byung Duk Min, Dong Chul Kim   +4 more
doaj   +1 more source

Senescence Is Associated With Elevated Intracellular Resting [Ca2 +] in Mice Skeletal Muscle Fibers. An in vivo Study

Frontiers in Physiology, 2021
Aging causes skeletal muscles to become atrophied, weak, and easily fatigued. Here, we have tested the hypothesis that normal aging in skeletal muscle cells is associated with Ca2+ intracellular dyshomeostasis and oxidative stress.
Alfredo Mijares, Paul D. Allen, Jose R. Lopez   +2 more
doaj   +1 more source

Intracellular calcium leak lowers glucose storage in human muscle, promoting hyperglycemia and diabetes

eLife, 2020
Most glucose is processed in muscle, for energy or glycogen stores. Malignant Hyperthermia Susceptibility (MHS) exemplifies muscle conditions that increase [Ca2+]cytosol. 42% of MHS patients have hyperglycemia.
Eshwar R Tammineni, Natalia Kraeva, Lourdes Figueroa, Carlo Manno, Carlos A Ibarra, Amira Klip, Sheila Riazi, Eduardo Rios   +7 more
doaj   +1 more source

Prevalence of malignant hyperthermia diagnosis in obstetric patients in the United States, 2003 to 2014

BMC Anesthesiology, 2020
Background The cost-benefit of stocking dantrolene in maternity units for treating malignant hyperthermia (MH) has been recently questioned because of the low incidence of MH crisis in the general population and the low utilization of general anesthesia ...
Jean Guglielminotti, Henry Rosenberg, Guohua Li   +2 more
doaj   +1 more source