Results 21 to 30 of about 2,263,022 (327)

Living, Caring, Learning – Early education, active lives and tailored treatment in haemophilia care

The Journal of Haemophilia Practice, 2023
Josipa, a haemophilia nurse in Croatia, describes how meeting 18-year-old twins with severe haemophilia A changed her views around joint health and activity in people with haemophilia.
Belev Josipa
doaj   +1 more source

DosEmi study protocol: a phase IV, multicentre, open-label, crossover study to evaluate non-inferiority of pharmacokinetic-guided reduced dosing compared with conventional dosing of emicizumab in people with haemophilia A

BMJ Open, 2023
Introduction Emicizumab effectively prevents bleeding in people with haemophilia A (PwHA), but is a burden for national healthcare budgets and consequently may limit access.
Marjon H Cnossen, Karin Fijnvandraat, Ron Mathot, Antoine C G Egberts, Rolf T Urbanus, Anouk Donners, Konrad van der Zwet, Ilmar Kruis, Roger Schutgens, Kathelijn Fischer   +9 more
doaj   +1 more source

The usefulness of c-Kit in the immunohistochemical assessment of melanocytic lesions [PDF]

, 2011
C-Kit (CD117), the receptor for the stem cell factor, a growth factor for melanocyte migra- tion and proliferation, has shown differential immunostaining in various benign and malig- nant melanocytic lesions. The purpose of this study is to compare c-Kit
Atzori L, Bianco P, Cabras S, Castellanos ME, Difelice E, Faa G, Ferreli C, Mulas P, Nemolato S, Pilloni L   +9 more
core   +1 more source

Predicting Individual Changes in Terminal Half-Life After Switching to Extended Half-Life Concentrates in Patients With Severe Hemophilia

HemaSphere, 2022
Predicting individual effects of switching from standard half-life (SHL) to extended half-life (EHL) FVIII/FIX concentrates is pivotal in clinical care, but large-scale individual data are scarce. The aim of this study was to assess individual changes in
Olav Versloot, Emma Iserman, Pierre Chelle, Federico Germini, Andrea N. Edginton, Roger E. G. Schutgens, Alfonso Iorio, Kathelijn Fischer, on behalf of the prophylaxis working group of the International Prophylaxis Study Group*   +8 more
doaj   +1 more source

How benign is benign overfitting?

, 2020
We investigate two causes for adversarial vulnerability in deep neural networks: bad data and (poorly) trained models. When trained with SGD, deep neural networks essentially achieve zero training error, even in the presence of label noise, while also exhibiting good generalization on natural test data, something referred to as benign overfitting [2 ...
Sanyal, A, Dokania, P, Kanade, V, Torr, P   +3 more
openaire   +3 more sources

Possible Targets to Reduce Fatigue in Chronic Immune Thrombocytopenia Patients – An Explorative Study

TH Open, 2022
Background Fatigue in immune thrombocytopenia (ITP) is frequent and burdensome, but we lack the knowledge to help these patients. Aim The aim of the study is to explore the role of disease activity and other potentially modifiable factors in ...
Wobke E.M. van Dijk, Merel M. Nap-van der Vlist, Hans Knoop, Roger E.G. Schutgens   +3 more
doaj   +1 more source

Dual time-point FDG PET/CT for differentiating benign from malignant solitary pulmonary nodules in a TB endemic area [PDF]

, 2010
Objective. Fluorodeoxyglucose (FDG)-positron emission tomography (PET) is an accurate non-invasive imaging test for differentiating benign from malignant solitary pulmonary nodules (SPNs).
Maes, Alex, Pottel, Hans, Sathekge, Mike Machab, Stoltz, Anton, Van De Wiele, Christophe   +4 more
core   +3 more sources

Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta) [PDF]

, 2017
Naturally occurring mammary tumours are uncommon in prosimians. A 20-year-old female ring-tailed lemur (Lemur catta) developed bilateral enlargement of the mammary glands.
De Los Monteros, A E, Grau-Bassas, E R, Herráez, P, Priestnall, S L, Quesada-Canales, O, Suárez-Bonnet, A   +5 more
core   +1 more source

Direct-to-Patient Survey for Diagnosis of Benign Paroxysmal Positional Vertigo [PDF]

, 2019
Given the high incidence of dizziness and its frequent misdiagnosis, we aim to create a clinical support system to classify the presence or absence of benign paroxysmal positional vertigo with high accuracy and specificity.
Friedland, David, Povinelli, Richard J., Richburg, Heidi   +2 more
core   +2 more sources

Developmental Venous Anomaly: Benign or Not Benign

Neurologia medico-chirurgica, 2016
Developmental venous anomalies (DVAs), previously called venous angiomas, are the most frequently encountered cerebral vascular malformations. However, DVA is considered to be rather an extreme developmental anatomical variation of medullary veins than true malformation. DVAs are composed of dilated medullary veins converging centripetally into a large
Rie Aoki, Kittipong Srivatanakul
openaire   +4 more sources