Results 51 to 60 of about 70,554 (240)

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

open access: yesChemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

α1L-adrenoceptors mediate contraction of human erectile tissue [PDF]

open access: yes, 2018
α1-adrenoceptor antagonists can impact upon sexual function and have potential in the treatment of erectile dysfunction. Human erectile tissue contains predominantly α1A-adrenoceptors, and here we examined whether contractions of this tissue are mediated
Campbell, Alistair   +6 more
core   +1 more source

Focused Ultrasound‐Induced Mechanical Ablation Affects the Carbohydrate Metabolism of Residual/Peri‐Focally Localized Glioblastoma Cells

open access: yesInternational Journal of Cancer, EarlyView.
Glioblastoma (GBM) is highly aggressive and therapy‐resistant, warranting exploration of novel treatment strategies, among them mechanical high‐intensity focused ultrasound (mFUS), which holds significant promise for tumor ablation. The present study examined mFUS‐induced changes specifically in carbohydrate metabolism, which affects vulnerability to ...
Frieda Bayler   +10 more
wiley   +1 more source

A case of giant prostatic hyperplasia

open access: yesAsian Journal of Urology, 2016
Benign prostatic hyperplasia (BPH) is one of the most common conditions experienced by aging males and a frequent cause of bladder outlet obstruction and macroscopic haematuria.
Luke Wang, Paul Davis, Kevin McMillan
doaj   +1 more source

Ultrasound‐Guided Transperineal Versus Transrectal Prostate Aspiration Biopsy in Diagnosing Prostate Cancer

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Background Ultrasound‐guided prostate biopsy is the standard method for the diagnosis of prostate cancer. However, the effect of the optimal puncture approach on diagnostic yield and patient outcomes remains controversial. Objective To compare the diagnostic effectiveness and clinical outcomes of ultrasound‐guided transperineal versus transrectal ...
Yue Cao, Hong Zhu, Junwei Wu
wiley   +1 more source

A MICROBIAL CONTAMINATION OF PROSTATIC TISSUE IN BENIGN PROSTATIC HYPERPLASIA AND PROSTATE CANCER

open access: yesВестник урологии, 2013
Bacteriological results of prostatic tissue in benign prostatic hyperplasia and prostate cancer are shown in this article. A use of extended amount of media for bacterial isolation allows a wide spectrum of nonclostridial anaerobic (Bacteroides sp ...
Y. L. Naboka   +2 more
doaj   +1 more source

Benign Prostatic Hyperplasia and Prostate Cancer [PDF]

open access: yesEpidemiologic Reviews, 2001
This paper reviews the epidemiologic studies of benign prostatic hyperplasia in relation to prostate cancer. Such relation was investigated in epidemiologic studies but none have provided clear evidence suggesting an etiologic role for benign prostatic hyperplasia in the development of prostatic cancer.
openaire   +2 more sources

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Successful treatment of complicated benign prostatic hyperplasia in a diabetic patient with water vapor thermal therapy and urethral stenting

open access: yesUrology Case Reports, 2019
Water Vapor Thermal Therapy is a novel, office-based procedure which has gained traction as first line therapy in specific therapeutic cases of benign prostatic hyperplasia.
Tej J. Desai, Jared J. Wallen
doaj   +1 more source

Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer. [PDF]

open access: yes, 2018
The introduction of serum Prostate Specific Antigen (PSA) testing nearly 30 years ago has been associated with a significant shift towards localized disease and decreased deaths due to prostate cancer.
Auman, Heidi   +16 more
core   +2 more sources

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