Results 141 to 150 of about 3,218,036 (364)

Operator splitting for the Benjamin-Ono equation

open access: yes, 2015
In this paper we analyze operator splitting for the Benjamin-Ono equation, u_t = uu_x + Hu_xx, where H denotes the Hilbert transform. If the initial data are sufficiently regular, we show the convergence of both Godunov and Strang splitting.Comment: 18 ...
Dutta, R.   +3 more
core  

A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness

open access: yesAdvanced Science, EarlyView.
This study identifies a sub‐circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub‐circuit is labeled by the clock output molecule mWAKE, which suppresses its excitability in a time‐dependent manner. mWAKE‐expressing cells in the SCN (SCNmWAKE cells) project to the subparaventricular zone (SPZ) to mediate ...
Qiang Liu   +6 more
wiley   +1 more source

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

open access: yesAdvanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao   +20 more
wiley   +1 more source

Microphysiological Solid Tumor Models in Hydrogel Beads for CAR T Cell Immunotherapy Evaluation

open access: yesAdvanced Science, EarlyView.
The complex physical and biochemical barriers of the tumor microenvironment are major triggers of immune exclusion. Here, a 3D micrometastasis model is developed to mimic key microenvironmental cues, enabling in vitro evaluation of chimeric antigen receptor (CAR) T cell immunotherapy. Abstract Micrometastases are challenging to resect surgically and to
Xuan Peng   +14 more
wiley   +1 more source

Ur phänomen y su transposición:: Benjamin y el Idealismo goetheano

open access: yesIdeas y Valores, 2007
Una lectura de la "Erkenntnis-kritische Vorrede" a Ursprung des deutsches Trauerspiels busca determinar en qué sentido Benjamin efectúa, en la teoría de las ideas allí esbozada, lo que él mismo llamó después una "tranposicion" del concepto goetheano de ...
Tupac Cruz
doaj  

Lendo: Benjamin [PDF]

open access: yesLua Nova: Revista de Cultura e Política, 1992
openaire   +4 more sources

Analyses of GWAS and Sub‐Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk

open access: yesAdvanced Science, EarlyView.
A cost‐effective strategy is developed analyzing sub‐threshold GWAS loci (5 × 10−8 < P ≤ 10−6), identifying 180 risk loci and 304 high‐confidence genes through combined GWAS/subGWAS analysis. This approach reveals dendrite development and morphogenesis (DDM) as a novel SCZ pathway.
Rui Chen   +15 more
wiley   +1 more source

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