Prim@ Facie, 2016 O presente trabalho objetiva acentuar as relações existentes entre o pragmatismo jurídico de Benjamin Cardozo e a filosofia pragmática de Charles S. Peirce e William James, isto é, tenta responder se a versão jurídica do pragmatismo foi influenciada por ...
Kleverton Halleysson Bibiano de Oliveira +1 more
doaj +9 more sources
CD8+ T cells control SIV infection using both cytolytic effects and non-cytolytic suppression of virus production [PDF]
Nature Communications, 2023 Whether CD8+ T lymphocytes control human immunodeficiency virus infection by cytopathic or non-cytopathic mechanisms is not fully understood. Multiple studies highlighted non-cytopathic effects, but one hypothesis is that cytopathic effects of CD8+ T ...
Benjamin B. Policicchio +11 more
doaj +2 more sources
Usefulness of FAPα assessment in bronchoalveolar lavage as a marker of fibrogenesis: results of a preclinical study and first report in patients with idiopathic pulmonary fibrosis [PDF]
Respiratory Research, 2023 Background Fibroblast activation protein-α (FAPα) is a marker of activated fibroblasts that can be selectively targeted by an inhibitor (FAPI) and visualised by PET/CT imaging. We evaluated whether the measurement of FAPα in bronchoalveolar lavage fluids
Philomène Lavis +16 more
doaj +2 more sources
Serum biomarkers and anti-flavivirus antibodies at presentation as indicators of severe dengue. [PDF]
PLoS Neglected Tropical Diseases, 2023 BackgroundDengue is the most common vector-borne viral disease worldwide. Most cases are mild, but some evolve into severe dengue (SD), with high lethality.
Cynthia Bernal +14 more
doaj +2 more sources
Chemerin plasma levels are increased in COVID-19 patients and are an independent risk factor of mortality [PDF]
Frontiers in Immunology, 2022 BackgroundChemerin is an extracellular protein with chemotactic activities and its expression is increased in various diseases such as metabolic syndrome and inflammatory conditions.
Philomène Lavis +24 more
doaj +2 more sources
The fibroblast activation protein alpha as a biomarker of pulmonary fibrosis [PDF]
Frontiers in MedicineIdiopathic pulmonary fibrosis (IPF) is a rare, chronic, and progressive interstitial lung disease with an average survival of approximately 3 years. The evolution of IPF is unpredictable, with some patients presenting a relatively stable condition with ...
Philomène Lavis +6 more
doaj +2 more sources
SP-D and CC-16 Pneumoproteins' Kinetics and Their Predictive Role During SARS-CoV-2 Infection [PDF]
Frontiers in Medicine, 2022 BackgroundSurfactant protein D (SP-D) and pulmonary club cell protein 16 (CC-16) are called “pneumoproteins” and are involved in host defense against oxidative stress, inflammation, and viral outbreak.
Margherita Tiezzi +21 more
doaj +2 more sources
The Dual Role of Chemerin in Lung Diseases [PDF]
CellsChemerin is an atypical chemokine first described as a chemoattractant agent for monocytes, natural killer cells, plasmacytoid and myeloid dendritic cells, through interaction with its main receptor, the G protein-coupled receptor chemokine-like receptor
Philomène Lavis +2 more
doaj +2 more sources
Characterization of Dengue Virus 4 Cases in Paraguay, 2019–2020 [PDF]
VirusesIn 2019–2020, dengue virus (DENV) type 4 emerged to cause the largest DENV outbreak in Paraguay’s history. This study sought to characterize dengue relative to other acute illness cases and use phylogenetic analysis to understand the outbreak’s origin ...
Alejandra Rojas +21 more
doaj +2 more sources
Acknowledgment of Reviewers 2021 [PDF]
Neurotrauma Reports, 2022 Critical evaluations of articles by expert reviewers make a vital contribution to ensuring the high quality of a journal's content. The editorial leadership of Neuotrauma Reports is very grateful for the support of the highly qualified peer reviewers ...
doaj +2 more sources