Results 171 to 180 of about 46,343 (254)

A Simple Parallel Screening Method for Gas–Solid Photodegradation Catalysis

open access: yesChemistry–Methods, Volume 6, Issue 8, August 2026.
This work describes a facile option for preliminary‐stage testing of various heterogenous photocatalytic materials or conditions, using a conventional hot dog cooker to provide uniform heating and rotation of sealed vials irradiated from above. Varying conditions can be tested in parallel, and we find this method particularly useful for gas‐solid ...
Carly J. Frank, Juan C. Scaiano
wiley   +1 more source

Mechanochemistry as an Emerging Tool for Organofluorine Chemistry

open access: yesChemistry–Methods, Volume 6, Issue 8, August 2026.
Fluorinated scaffolds are central across many areas of chemistry, driving the demand for efficient and sustainable synthetic methods. Mechanochemistry has emerged as a powerful alternative to conventional approaches, offering reduced environmental impact, shorter reaction times, and unique reactivity and selectivity.
Marie Caldiero   +3 more
wiley   +1 more source

Structure‐Based Design, Synthesis, and Biological Evaluation of Oxadiazole–Morpholine Hybrids as Potent PARP‐1 Inhibitors Inducing Apoptosis in Breast Cancer Cells

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Poly(ADP‐ribose) polymerase‐1 (PARP‐1) plays a central role in the repair of DNA single‐strand breaks and represents an established therapeutic target in cancer treatment. In this study, a series of novel oxadiazole–morpholine hybrid compounds was designed and synthesized using a structure‐based drug design approach to target the catalytic ...
Nader R. Albujuq   +6 more
wiley   +1 more source

Discovery of a Potent and Selective MAO‐B Inhibitor From a Donepezil‐Linked Chalcone Library With Promising Antiparkinsonian Activity

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A focused library of 19 donepezil‐linked chalcones (DLCs) was efficiently synthesised through microwave‐assisted Claisen‐Schmidt condensation and subsequently profiled for their inhibitory activities against cholinesterases (AChE and BuChE) as well as monoamine oxidases (MAO‐A and MAO‐B).
Azize Kirac‐Aydin   +11 more
wiley   +1 more source

A Woman With Continuous, Involuntary, Unilateral Movement. [PDF]

open access: yesJ Am Coll Emerg Physicians Open
Che R, Patel S, Edwards M, Wilson M.
europepmc   +1 more source

Identification of Volatile Odor Compounds in Extracts of Four Types of Herbaceous Plant Spices via GC × GC–O‐TOF MS

open access: yeseFood, Volume 7, Issue 4, August 2026.
In this study, sensory evaluation, electronic nose, solid‐phase microextraction, and comprehensive two‐dimensional gas chromatography‐olfactometry‐time‐of‐flight mass spectrometry were used to analyze the volatile compounds and key odor‐active components in the extracts of sour horn, alfalfa, chicory, and fenugreek, and a total of 59 odor‐active ...
Suxing Tuo   +11 more
wiley   +1 more source

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