Results 11 to 20 of about 8,932 (201)

Synthesis and Disinfection Effect of the Pyridine-4-aldoxime Based Salts [PDF]

Molecules, 2015
A set of new quaternary ammonium compounds based on pyridine-4-aldoxime was synthesized, characterized with analytical data (NMR, EA, HPLC, MS) and tested for in vitro antimicrobial activity (antibacterial, antifungal) and cytotoxicity.
Jan Marek, David Malinak, Rafael Dolezal, Ondrej Soukup, Marketa Pasdiorova, Martin Dolezal, Kamil Kuca   +6 more
doaj   +5 more sources

Benzalkonium chloride (BAC) and dimethyldioctadecyl-ammonium bromide (DDAB), two common quaternary ammonium compounds, cause genotoxic effects in mammalian and plant cells at environmentally relevant concentrations [PDF]

Mutagenesis, 2007
Quaternary ammonium compounds (QACs) are cationic surfactants that are widely used as disinfectants. In the present study, we tested two important representatives, namely, benzalkonium chloride (BAC) and dimethyldioctadecyl-ammonium bromide (DDAB) in four genotoxicity tests, namely, in the Salmonella/microsome assay with strains TA 98, TA 100 and TA ...
Wolfram Parzefall, Tamara Grummt, Siegfried Knasmüller, Veronika Ehrlich, Karol Mičieta, Armen Nersesyan, M. Mišík, Franziska Ferk, Britta Grillitsch, Maria Uhl, Maria Fuerhacker, Christine Hoelzl   +11 more
openaire   +4 more sources

The toxicity of the quaternary ammonium compound benzalkonium chloride alone and in mixtures with other anionic compounds to bacteria in test systems with Vibrio fischeri and Pseudomonas putida

Ecotoxicology and Environmental Safety, 2008
Mixtures of chemicals are present in the aquatic environment but standard testing methods assess only single compounds. One aspect of this question is the importance of the formation of ionic pairs, for example from quaternary ammonium compounds with organic anions, and the significance of the ionic pairs for bacterial toxicity in the aquatic ...
Sütterlin, Heike, Alexy, Radka, Kümmerer, Klaus   +2 more
openaire   +5 more sources

Analysis of Genetic Determinants Encoding Resistance to Heavy Metals and Disinfectants in Listeria monocytogenes [PDF]

Foods
Listeria monocytogenes is an important foodborne pathogen causing listeriosis. L. monocytogenes, existing in the natural environment, can also contaminate food products, which poses a serious threat to human health and life, especially for high-risk ...
Elżbieta Maćkiw, Joanna Kowalska, Dorota Korsak, Jacek Postupolski   +3 more
doaj   +2 more sources

Imidazoles and Quaternary Ammonium Compounds as Effective Therapies against (Multidrug-Resistant) Bacterial Wound Infections [PDF]

Antibiotics
Background/Objectives: The rise and spread of antimicrobial resistance complicates the treatment of bacterial wound pathogens, further increasing the need for newer, effective therapies.
Lauren Van de Vliet, Thijs Vackier, Karin Thevissen, David Decoster, Hans P. Steenackers   +4 more
doaj   +2 more sources

Eco-Friendly Spectrophotometric Methods for Resolving the Spectral Inference of Benzalkonium Chloride During Alcaftadine and Ketorolac Tromethamine Quantification. [PDF]

Anal Sci Adv
ABSTRACT The pharmaceutical industry has recently introduced a new combination of eye drop containing alcaftadine (ALF) and ketorolac tromethamine (KTC) utilized in managing allergic conjunctivitis. This new formulation elevates the necessity for developing sensitive, reliable, rapid and simple spectrophotometric methods to accurately quantify ALF and ...
Hussein OG, Rezk MR, Logoyda L, Wadie M.
europepmc   +2 more sources

Analyze the toxicities of benzalkonium chloride as a COVID-19 disinfectant in physiological goldfish (Carassius auratus) [PDF]

Veterinary World, 2023
Background and Aim: Coronavirus disease-2019 (COVID-19) impacts increasing the use of disinfectants (benzalkonium chloride), which indirectly accumulate in water.
Sisilia Rivanda Arianto, Fendi Aprian Syah, Luthfiana Aprilianita Sari, Ayu Lana Nafisyah, Sulastri Arsad, Nadirah Musa   +5 more
doaj   +1 more source

Use Pattern of Ophthalmic Antiglaucoma Agents with and without Preservatives: A Cross-Sectional Study

Pharmaceuticals, 2023
Background: Different drugs have been approved to reduce the intraocular pressure. However, most of them contain preservatives to maintain sterility and these can be toxic to the ocular surface.
Luis Fernando Valladales-Restrepo, María Camila Oyuela-Gutiérrez, Ana Camila Delgado-Araujo, Jorge Enrique Machado-Alba   +3 more
doaj   +1 more source

Assessment of Resistance in Burkholderia pseudomallei to Benzalkonium Chloride and Antibiotics

Проблемы особо опасных инфекций, 2022
The aim of the study was to investigate the features of resistance formation in Burkholderia pseudomallei to quaternary ammonium compounds, as well as to analyze its influence on the development of antibiotic resistance.Materials and methods.
D. N. Luchinin, E. V. Molchanova, I. B. Zakharova, D. V. Viktorov   +3 more
doaj   +1 more source

Comparative Evaluation of the Effects of Binzalkonium Chloride, Iodine, Gluteraldehyde and Hydrogen Peroxide Disinfectants against Avian Salmonellae Focusing on Genotypic Resistance Pattern of the Salmonellae Serotypes toward Benzalkonium Chloride [PDF]

Brazilian Journal of Poultry Science, 2020
Using disinfectants in poultry houses is a common practice to ban the zoonotic pathogens like Salmonella. A major concern in using disinfectants is the emergence of bacteria strains that resist some disinfectants.
A Aksoy, KEM El Kahlout, H Yardimci
doaj   +1 more source