Results 41 to 50 of about 14,478 (208)

Evaluation of the cytotoxic effects of ophthalmic solutions containing benzalkonium chloride on corneal epithelium using an organotypic 3-D model [PDF]

, 2009
Background Benzalkonium chloride (BAC) is a common preservative used in ophthalmic solutions. The aim of this study was to compare the cytotoxic effects of BAC-containing ophthalmic solutions with a BAC-free ophthalmic solution using an organotypic 3 ...
Jessen Bart A, Khoh-Reiter Su
core   +1 more source

Antimicrobial efficacy and compatibility of solid copper alloys with chemical disinfectants. [PDF]

PLoS ONE, 2018
INTRODUCTION:Chemical disinfection is state of the art in preventing spread of infectious agents in the healthcare setting. Additionally, the antimicrobial properties of solid copper alloy surfaces against various microorganisms have recently been ...
Katrin Steinhauer, Sonja Meyer, Jens Pfannebecker, Karin Teckemeyer, Klaus Ockenfeld, Klaus Weber, Barbara Becker   +6 more
doaj   +1 more source

Antibacterial and resistance-modifying activities of thymoquinone against oral pathogens [PDF]

, 2011
Background The presence of resistant bacteria in the oral cavity can be the major cause of dental antibiotic prophylaxis failure. Multidrug efflux has been described for many organisms, including bacteria and fungi as part of their drugs resistance ...
Bochra Kouidhi, Tarek Zmantar, Hanene Jrah, Yosra Souiden, Kamel Chaieb, Kacem Mahdouani, Amina Bakhrouf   +6 more
core   +2 more sources

Wide-Antimicrobial Spectrum of Picolinium Salts

Molecules, 2020
Nosocomial infections, which greatly increase morbidity among hospitalized patients, together with growing antibiotic resistance still encourage many researchers to search for novel antimicrobial compounds.
Sarka Salajkova, Marketa Benkova, Jan Marek, Radek Sleha, Lukas Prchal, David Malinak, Rafael Dolezal, Kristina Sepčić, Nina Gunde-Cimerman, Kamil Kuca, Ondrej Soukup   +10 more
doaj   +1 more source

Biocide exposure induces changes in susceptibility, pathogenicity and biofilm formation in Uropathogenic Escherichia coli [PDF]

, 2019
Background: Uropathogenic Escherichia coli (UPEC) are a frequent cause of catheter associated urinary tract infection (CAUTI). Biocides have been incorporated into catheter-coatings to inhibit bacterial colonisation whilst ideally exhibiting low ...
Dowling, John, Forbes, S, Henly, Emma, Lacey, Melissa, Maingay, JB, Smith, Thomas   +5 more
core   +1 more source

Benzalkonium chloride (BAC) and dimethyldioctadecyl-ammonium bromide (DDAB), two common quaternary ammonium compounds, cause genotoxic effects in mammalian and plant cells at environmentally relevant concentrations [PDF]

Mutagenesis, 2007
Quaternary ammonium compounds (QACs) are cationic surfactants that are widely used as disinfectants. In the present study, we tested two important representatives, namely, benzalkonium chloride (BAC) and dimethyldioctadecyl-ammonium bromide (DDAB) in four genotoxicity tests, namely, in the Salmonella/microsome assay with strains TA 98, TA 100 and TA ...
F, Ferk, M, Misík, C, Hoelzl, M, Uhl, M, Fuerhacker, B, Grillitsch, W, Parzefall, A, Nersesyan, K, Micieta, T, Grummt, V, Ehrlich, S, Knasmüller   +11 more
openaire   +2 more sources

Toxicity of antiglaucoma drugs with and without benzalkonium chloride to cultured human corneal endothelial cells [PDF]

, 2010
Masahiko Ayaki1, Atsuo Iwasawa2, Yoichi Inoue31Department of Ophthalmology, Saitama National Hospital, Wako, Japan; 2Life Particle Interaction Engineering Creation, New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan; 3Department of ...
Masahiko Ayaki, Atsuo Iwasawa, Yoichi Inoue   +2 more
core   +2 more sources

Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects

Animal Models and Experimental Medicine, EarlyView.
Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu, Jiaqi Chen, Zhonghui Li, Jiamin Zhou, Hui Zhang, Yujia Yu, Feng Cheng, Jie Bao, Chunhan Feng, Xiangqu Yu, Zhao Xia, Rao Ding, Xiang Li   +12 more
wiley   +1 more source

Fluconazole-Pyridoxine Bis-Triazolium Compounds with Potent Activity against Pathogenic Bacteria and Fungi Including Their Biofilm-Embedded Forms

Journal of Chemistry, 2017
Two novel quaternary ammonium salts, bis-triazolium derivatives of fluconazole and pyridoxine, were synthesized by reaction of fluconazole with pyridoxine-based synthetic intermediates.
Marsel R. Garipov, Roman S. Pavelyev, Svetlana A. Lisovskaya, Elena V. Nikitina, Airat R. Kayumov, Alina E. Sabirova, Oksana V. Bondar, Albina G. Malanyeva, Alexander M. Aimaletdinov, Alfia G. Iksanova, Konstantin V. Balakin, Yurii G. Shtyrlin   +11 more
doaj   +1 more source

Comparison of Gene Expression Profiles of Uropathogenic Escherichia Coli CFT073 after Prolonged Exposure to Subinhibitory Concentrations of Different Biocides

Antibiotics, 2019
Biocides are chemical compounds widely used for sterilization and disinfection. The aim of this study was to examine whether exposure to subinhibitory biocide concentrations influenced transcriptional expression of genes that could improve a pathogen ...
Małgorzata Ligowska-Marzęta, Viktoria Hancock, Hanne Ingmer, Frank M. Aarestrup   +3 more
doaj   +1 more source