Results 121 to 130 of about 20,936 (236)

N-{[(4-Nitrophenyl)amino]methyl}benzamide

open access: yes, 2014
We report the synthesis of N-{[(4-nitrophenyl)amino]methyl}benzamide from (benzamidomethyl)triethylammonium chloride and 4-nitroaniline in aqueous media.
Emil Popovski   +2 more
core   +1 more source

Cholesterol and Cholesterol‐Derived Molecules Differentially Modulate Neuronal Kv7.2/7.3 Channels

open access: yesArchiv der Pharmazie, Volume 359, Issue 6, June 2026.
Cholesterol, steroid hormones, and cholesterol‐based imidazolium salts (CHIMs) inhibit Kv7.2/Kv7.3 channels. Notably, NBD‐tagged CHIM‐L enhances currents. These findings demonstrate that both chemical modifications and linker length differentially modulate Kv7 activity, revealing variant‐specific sensitivities and potential pharmacological targets for ...
Elif Karabatak   +6 more
wiley   +1 more source

Molecular Docking Study of Substituted Benzamide Derivatives as Analgesic Candidates

open access: yes
Thiourea derivatives represent a diverse class of compounds exhibiting a range of pharmacological activities, including antitubercular, analgesic, antiviral, and anticancer effects.
Muammar Fawwaz   +5 more
core   +1 more source

Iridium‐Catalyzed Linear‐Selective sp3 C−H Alkylation of N‐Methylamides Using Alkenes Enabled by Diphosphite Ligands

open access: yesChemistry – A European Journal, Volume 32, Issue 21, 1 June 2026.
An iridium‐catalyzed linear‐selective sp3 C─H alkylation of N‐methylamides with alkenes is described. This method tolerates various N‐methylacetamide derivatives and has a broad alkene scope. Mechanistic studies were also conducted. Internal alkenes can also be used through in situ consecutive alkene isomerization.
Haluhi Takahashi, Takanori Shibata
wiley   +1 more source

-(2-Aminophenyl)-benzamide Binding Unit

open access: yes, 2015
A novel series of potent chiral inhibitors of histone deacetylase (HDAC) is described that contains an oxazoline capping group and a N-(2-aminophenyl)-benzamide unit.
Marson, Charles M.   +9 more
core   +1 more source

Delivering Proteins and Enzymes to Solid Tumors Through the Development of Stimuli‐Responsive Nanocarriers

open access: yesChemNanoMat, Volume 12, Issue 6, June 2026.
Stimuli‐responsive strategies to achieve controlled release of protein‐based therapeutic agents into solid tumors. Proteins, enzymes, and peptides have long been recognized as valuable therapeutic agents, particularly in oncology. However, their complex chemical structures render them more sensitive than smaller chemotherapeutic drugs.
Guillermo Plaza‐Palomo   +3 more
wiley   +1 more source

Bioactive Composition and Antioxidant and Glycemic‐Regulating Properties of Basella alba L. Leaf, Fruit, and Stem: GC–MS, FTIR, In Vitro and In Silico Insights

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
The bioactive composition, antioxidant capacity, and glycemic‐regulating properties of Basella alba L. leaf, fruit, and stem were comparatively analyzed using gas chromatography–mass spectrometry (GC–MS), Fourier‐transform infrared spectroscopy (FTIR), in vitro assays, and molecular docking analyses.
Shorna Das   +4 more
wiley   +1 more source

2-(Difluoroboryloxy)benzamide

open access: yesMolbank
The title compound has been fully characterised by NMR for the first time. Fully assigned 1H and 13C NMR spectra, and the X-ray structure of two different polymorphs are presented. The polymorphs show similar molecular geometries but exhibit significantly different patterns of intermolecular interactions.
R. Alan Aitken   +4 more
openaire   +2 more sources

Vacuolization as a Novel Approach to Cancer Therapy

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak   +9 more
wiley   +1 more source

Deletion of a Pax1 Sex‐Associated Genomic Region Associated With Adolescent Idiopathic Scoliosis Leads to Disc Degeneration, Instability, and Vertebral Rotation in Mice

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Overview of the effects of Pax1‐SAR deletion on gene expression, IVD degeneration, and resultant scoliotic‐like curvature between sexes. Proposed mechanism of sex‐dependent changes in gene expression in females (right) and males (left), resulting in sex‐dependent disc degeneration and scoliotic phenotypes.
Edward C. Moody   +4 more
wiley   +1 more source

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