Results 121 to 130 of about 33,916 (231)

Controlling the Morphology of Aggregates of an Amphiphilic Synthetic Receptor through Host-Guest Interactions [PDF]

, 2006
A new amphiphilic receptor containing a macrocyclic anionic headgroup and a single alkyl chain was prepared through an efficient templated synthesis. The interdependence of the aggregation behavior and the host-guest chemistry was studied. In the absence
Chhabra, Anjali,, Figueiras Gómez, Sergio,, Liu, Jingyuan,, Otto, Sijbren,, Skepper, Jeremy N.,, Suksai, Chomchai,, Tuntulani, Thawatchai,   +6 more
core   +2 more sources

A Novel Small Molecule Accelerates Early Persister Regrowth and Potentiates Antibiotic Killing via MdtL–DcrB

Microbial Biotechnology, Volume 19, Issue 5, May 2026.
bymBDZ accelerates early regrowth of persister‐derived E. coli and potentiates antibiotic killing. Its activity requires the MdtL–DcrB axis and is associated with envelope‐linked transport changes that increase intracellular small‐molecule exposure during recovery, thereby enhancing clearance in early treatment windows. ABSTRACT Persister cells survive
Garin Park, Hyein Kim, Sooyeon Song
wiley   +1 more source

Synthesis of 2‐Aryl(alkyl)benzimidazole Hydroxamic Acids as HDAC Inhibitors with Anti‐Angiogenesis Properties

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
2‐Aryl(alkyl)benzimidazole hydroxamic acids (11‐16) are potent and selective HDAC6 inhibitors, with minimal activity against HDAC1/2, and also display anti‐angiogenic and anticancer activities. Compound 13 exhibited a GI50 of 3.9 μM against EPCs and inhibited the growth of HCT‐116, SK‐Hep‐1, and PC‐3 cells with GI50 values of 1.3, 4.2, and 7.5 μM ...
Yi‐Ting Liu, Cheng‐Ta Lai, Shih‐Wei Wang, Shan‐Chi Liu, Yi‐Lin Hwang, Yi‐Chen Tsai, Chi‐Yeh Lee, Yu‐Wei Lai, Juei‐Yu Yen, Po‐Chuan Wang, Hsueh‐Yun Lee   +10 more
wiley   +1 more source

2-Chloro-N-(2,6-dichlorophenyl)benzamide

Acta Crystallographica Section E, 2008
In the structure of the title compound (N26DCP2CBA), C13H8Cl3NO, the conformations of N—H and C=O bonds in the amide group are trans to each other, similar to that observed in N-(2,6-dichlorophenyl)benzamide, 2-chloro-N-phenylbenzamide, 2-chloro-N-(
B. Thimme Gowda, Miroslav Tokarčík, Jozef Kožíšek, B. P. Sowmya, Hartmut Fuess   +4 more
doaj   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Triazine‐Based Dual Histone Deacetylase/phosphatidylinositol 3‐kinase Inhibitors for Breast Cancer Therapy

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Breast cancer is the most frequently diagnosed malignancy and a leading cause of cancer‐related mortality among women worldwide. Triple‐negative breast cancer (TNBC) poses a major clinical challenge due to its aggressive nature, limited therapeutic options, and high propensity for drug resistance.
Lara Luzietti, Gustavo Salgado Pires, Ana Ryan, Crisamie Regidor, Matthew Hiller, Danilo Sarti, Tríona Ní Chonghaile, Pedro de Sena Murteira Pinheiro, Damir Varešlija, Daniel Alencar Rodrigues   +9 more
wiley   +1 more source

Fair and Square: Design, Synthesis and Biological Evaluations of Squaric Acid Derivatives as Novel HDAC8 Inhibitors

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Histone deacetylase 8 (HDAC8) is a clinically validated target in neuroblastoma, where isoform selective inhibition offers a strategy to suppress tumour growth while limiting off‐target toxicity. Hydroxamic acids remain the dominant zinc‐binding group (ZBG) in HDAC inhibitors but are also associated with metabolic instability, suboptimal ...
Nathan Long, Franz‐Josef Meyer‐Almes, Aleksandra Kopranovic, Stephen P. Wren   +3 more
wiley   +1 more source

High performance mixed bisimide resins and composites based thereon [PDF]

, 1986
Mixtures of bismaleimide/biscitraconirnide resins produces materials which have better handling, processing or mechanical and thermal properties, particularly in graphite composites, than materials made with the individual resins. The mechanical strength
ations., Parker, J. A.
core   +1 more source

2-(Difluoroboryloxy)benzamide

Molbank
The title compound has been fully characterised by NMR for the first time. Fully assigned 1H and 13C NMR spectra, and the X-ray structure of two different polymorphs are presented. The polymorphs show similar molecular geometries but exhibit significantly different patterns of intermolecular interactions.
R. Alan Aitken, Hibet E. M. Akkache, David B. Cordes, Aidan P. McKay, Dorian Moreau   +4 more
openaire   +2 more sources

Nanoassemblies of an Artificial Ferric Enterobactin Analog for Biosensing Enterobacteriaceae

ChemElectroChem, Volume 13, Issue 8, 15 April 2026.
Nanoassemblies of an artificial trisamine‐based Ferric Enterobactin, analogs to natural enterobactin and ferric enterobactin, is reported as molecular recognition receptors for real‐time biosensing. The electrochemical sensors, made from the nanoassemblies of its iron(III)complex, exhibit rapid anodic peak current changes upon exposure to live cells of
Selina Laws, Ndepana Andrew, Robson L. Grosso, Matthew Carnaghi, Hemali Rathnayake   +4 more
wiley   +1 more source

Electrochemical Regioselective Chalcogenocyclizations of 2‐Alkynylbenzamides in Flow

ChemElectroChem, Volume 13, Issue 8, 15 April 2026.
A sustainable electrochemical method enables regioselective 6‐endo‐dig chalcogeno‐cyclizations of ortho‐alkynylbenzamides in continuous flow. Using diphenyl diselenide as an electroactive coupling partner, the process avoids metals and stoichiometric oxidants, offering scalable access to selenium‐containing heterocycles.
Hanaa Gieman, Sagar Arepally, Thomas Wirth   +2 more
wiley   +1 more source