Results 51 to 60 of about 6,963 (215)

Serum penicillin levels in Indian children and adolescents with rheumatic heart disease receiving benzathine penicillin G prophylaxis

Annals of Pediatric Cardiology
Background: Acute rheumatic fever and rheumatic heart disease (RHD) are serious complications of untreated Group A Streptococcal infections. Given that India bears the highest global burden of RHD, optimizing secondary prophylaxis is a public health ...
Kawaldeep Kaur, Sakshi Sachdeva, Dinesh Kumar, Thirumurthy Velpandian, Dheeraj Deo Bhatt   +4 more
doaj   +1 more source

Genetic Susceptibility to Rheumatic Heart Disease: A Narrative Literature Review Highlighting Evidence From African Populations and Research Gaps in Sudan

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Rheumatic heart disease (RHD) remains a significant public health burden in low‐ and middle‐income countries, particularly in sub‐Saharan Africa. Although socioeconomic factors contribute to disease persistence, genetic susceptibility plays a critical role in determining progression from Group A Streptococcal infection to ...
Hussam Alkhalifamohamed, Waleed M. A. Jebreel, Mohamed Elhassan, Sulafa K. M. Ali   +3 more
wiley   +1 more source

Progress towards the elimination of vertical transmission of HIV, syphilis and hepatitis B in 21 high‐burden countries

Journal of the International AIDS Society, Volume 29, Issue 4, April 2026.
Abstract Introduction Elimination of mother‐to‐child transmission (EMTCT) of HIV, syphilis and hepatitis B by 2030 is a global goal endorsed by countries. To achieve EMTCT, countries need to meet targets for programme and impact indicators. Methods We examined progress and gaps in service delivery across the three infections among 21 countries with a ...
Melanie M. Taylor, Rania A. Tohme, Robert McDonald, Michele Montandon   +3 more
wiley   +1 more source

Comparative Study of Oral Daily Amoxicillin, Long Acting Intramuscular Penicillin, and Tonsillectomy in Prevention of Recurrent Pharyngitis

Medicine Science, 2015
Pediatric recurrent pharyngitis represents a huge global health burden causing much morbidity and mortality in children. The aim of the study was to compare the efficacy of oral daily amoxicillin, intramuscular penicillin, and tonsillectomy in reducing ...
Amira S Ahmed, Engy A Wahsh, Essam Eldin G. Ahmed   +2 more
doaj   +1 more source

α‐Adrenergic blockade impairs ductus venosus shunting during an acute period of fetal hypoxaemia without further deficits to cerebral oxygen delivery

Experimental Physiology, Volume 111, Issue 4, Page 1796-1807, 1 April 2026.
Abstract The fetal circulation has unique shunts, including the ductus venosus (DV), the tone of which dictates how much substrate‐rich blood returning from the placenta is streamed preferentially away from the liver and instead towards the heart. Herein, we aimed to use clinically relevant MRI techniques in sheep to measure indirectly induced changes ...
Jack R. T. Darby, Stacey L. Holman, Brahmdeep S. Saini, Sunthara Rajan Perumal, Mike Seed, Christopher K. Macgowan, Janna L. Morrison   +6 more
wiley   +1 more source

Case Report: Detection of Treponema phagedenis in cerebrospinal fluid of a neurosyphilis patient by metagenomic next-generation sequencing

Frontiers in Cellular and Infection Microbiology, 2023
Treponema phagedenis, a human commensal spirochete, has been reported world-wide as a key factor in the pathogenesis of bovine digital dermatitis. Here we report a case of T.
Chenyan Yuan, Chenyan Yuan, Wei Xu, Wei Xu, Chenggui Zhao, Chenggui Zhao, Wei Gao, Wei Gao, Guoqiu Wu, Guoqiu Wu, Guoqiu Wu   +10 more
doaj   +1 more source

Methodological comparison of fetal brain 1H‐MRS data analysis techniques and gestational age analysis using LCModel in the fetal sheep brain

Experimental Physiology, Volume 111, Issue 4, Page 1597-1611, 1 April 2026.
Abstract Proton (1H) magnetic resonance spectroscopy (MRS) is a non‐invasive imaging technique that can be used to assess brain metabolism. Establishing reference levels of fetal brain metabolites in a translatable preclinical model is crucial for identifying subtle deviations from normal cerebral development. Herein, we developed a 1H‐MRS protocol for
Jordan A. Minns, Jack R. T. Darby, Georgia K. Williams, Jesse T. Tu, Ziqi Sun, Jessie Guo, Steven P. Miller, Christopher K. Macgowan, Mike Seed, Jamie Near, Janna L. Morrison   +10 more
wiley   +1 more source

Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment Failure

Case Reports in Obstetrics and Gynecology, 2018
We report a case of early latent syphilis (reactive serologic tests without clinical evidence of disease within 24 months from the onset of the infection) in pregnancy.
Lucia Pasquini, Elena Rita Magro-Malosso, Adalgisa Cordisco, Michele Trotta, Mariarosaria Di Tommaso   +4 more
doaj   +1 more source

Comparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea [PDF]

, 2018
Background: A dose of 30 mg/kg of azithromycin is recommended for treatment of yaws, a disease targeted for global eradication. Treatment with 20 mg/kg of azithromycin is recommended for the elimination of trachoma as a public health problem.
Abdulai, Abdul A, Addo, Kennedy K, Adu-Sarkodie, Yaw, Adwere, Paul, Asiedu, Kingsley, Ballard, Ronald, Basing, Laud A, Bauri, Mathias, Bieb, Sibauk V, Boateng, Laud, Bottomley, Christian, Chen, Cheng Y, Chi, Kai H, Danavall, Damien, Dua, Fredrick, Houinei, Wendy, Kwakye, Cynthia, Mabey, David CW, Marks, Michael, Miag, Helen, Mitjà, Oriol, Ohene, Sally-Ann, Pillay, Allan, Simpson, Shirley V, Solomon, Anthony W, study team, Wangi, James, Wangnapi, Regina   +27 more
core   +2 more sources

Low syphilis treatment rates and associated birth outcomes in pregnant women with and without HIV in Zambia: A cohort study

International Journal of Gynecology &Obstetrics, Volume 172, Issue 3, Page 1569-1575, March 2026.
Abstract Objective Syphilis and HIV in pregnancy contribute to adverse birth outcomes in Africa. Benzathine penicillin G remains an effective treatment for syphilis in pregnancy, yet gaps persist in timely treatment. The aim of this study was to compare factors associated with adverse birth outcomes among pregnant women diagnosed with syphilis in ...
Albert Manasyan, Anna V. Jones, Yumo Xue, Herbert Kapesa, Maureen Mzumara, Jodie A. Dionne, Mwangelwa Mubiana‐Mbewe   +6 more
wiley   +1 more source