Results 1 to 10 of about 6,963 (223)
Tolerability of IM penicillin G benzathine diluted or not with local anesthetics, or different gauge needles for syphilis treatment: a randomized clinical trial [PDF]
BMC Infectious Diseases, 2019 Background Penicillin G Benzathine (PGB) is the cornerstone of syphilis treatment. However, its intramuscular (IM) administration is associated with pain at the site of injection.
Vicente Estrada +14 more
doaj +2 more sources
Treatment of Syphilis in Pregnancy and Congenital Syphilis: Current Evidence, Challenges, and Future Directions [PDF]
AntibioticsSyphilis remains a global public health concern, with maternal infection posing a substantial risk for congenital syphilis, a preventable condition associated with severe morbidity and mortality.
Serena Salomè, Chryssoula Tzialla
doaj +2 more sources
Evaluation of Combined Strategy to Reduce the Pain of Penicillin G Benzathine Injection in Primary Syphilis [PDF]
Infection and Drug ResistanceYuxia Fang,1 Yilu Zhao,2 Lei Qin,1 Ziyue Song,1 Ruzhi Zhang1 1Department of Dermatology and STD, The Second Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, 241001, People’s Republic of China; 2Department of Dermatology, The First Affiliated ...
Fang Y, Zhao Y, Qin L, Song Z, Zhang R
doaj +2 more sources
Azithromycin versus penicillin G benzathine for early syphilis. [PDF]
Cochrane Database Syst Rev, 2012 Syphilis is a complex systemic disease caused by a spirochete, Treponema pallidum. The World Health Organization estimates that at least 12 million people worldwide are currently infected with syphilis. In this review we compared two current standards of treatment for early syphilis, benzathine benzylpenicillin (penicillin G) and azithromycin.To ...
Bai ZG +9 more
europepmc +5 more sources
Dermatology Reports, 2022 Background: Erysipelas is an acute infection due to S. pyogenes and is characterized by a high risk of relapses. The number of patients suffering from one or more recurrences varied depending on the study and accounted for between 16% and 47% of the ...
Agnieszka Bednarska +8 more
doaj +1 more source
Secondary Prevention of Rheumatic Heart Disease in Nepal: Are We Going Backward?
Journal of Nepal Medical Association, 2022 A secondary level of prophylaxis has proven to be the most successful in Nepal, a country with an endemic rate of rheumatic heart disease, in combating the severe issues associated with rheumatic heart disease.
Prakash Raj Regmi +2 more
doaj +1 more source
Cerebral syphilitic gumma presenting with intracranial gumma and pathologic vertebrae fractures
Radiology Case Reports, 2021 A 37-year-old female was admitted with worsening neurologic function. On arrival from an outside hospital, the patient was obtunded and intubated. Magnetic resonance imaging of the brain revealed nodular enhancement of the leptomeninges, intracranial ...
Ryan Thibodeau, MPH +5 more
doaj +1 more source
Case Reports, 2022 Introduction: Congenital syphilis is a major public health problem, and early diagnosis and treatment are necessary to prevent it. Penicillin G benzathine is the treatment of choice in pregnant women; however, it may fail to prevent fetal infection, as ...
Mery Yolanda Cifuentes Cifuentes +4 more
doaj +1 more source
, 2014 INTRODUCTION: Yaws, caused by Treponema pallidum ssp. pertenue, is endemic in parts of West Africa, Southeast Asia and the Pacific. The WHO has launched a campaign based on mass treatment with azithromycin, to eradicate yaws by 2020.
Asiedu, Kingsley B +4 more
core +7 more sources
Prevalence study of yaws in the Democratic Republic of Congo using the lot quality assurance sampling method. [PDF]
, 2009 BACKGROUND: Until the 1970s the prevalence of non-venereal trepanomatosis, including yaws, was greatly reduced after worldwide mass treatment. In 2005, cases were again reported in the Democratic Republic of the Congo. We carried out a survey to estimate
Dhorda, M +9 more
core +11 more sources