Results 1 to 10 of about 20,767 (160)

Treponema pallidum protein Tp0136 promotes angiogenesis to facilitate the dissemination of Treponema pallidum [PDF]

Emerging Microbes and Infections
The incompletely eliminated Treponema pallidum (T. pallidum) during primary syphilis chancre infection can result in the progression of secondary, tertiary, or latent syphilis in individuals, suggesting that T. pallidum has successfully evaded the immune
Xi Luo, Xin-Qi Zheng, Qiu-Ling Li
exaly   +4 more sources

Genomic Analysis of Doxycycline Resistance–Associated 16S rRNA Mutations in Treponema pallidum Subspecies pallidum [PDF]

Emerging Infectious Diseases
We inspected 16S rRNA sequences of 784 publicly available Treponema pallidum subspecies pallidum genomes and 17 new T. pallidum subsp. pallidum genomes from Canada for putative mutations associated with doxycycline resistance.
George S. Long, Mackenzie Neale, Thomas Braukmann, Vanessa Tran, Nishant Singh, Vanessa Allen, Muhammad Morshed, Jessica Minion, Paul Van Caeseele, Maud Vallée, Todd Hatchette, Samir N. Patel, Raymond S.W. Tsang, Venkata R. Duvvuri   +13 more
doaj   +2 more sources

Detection of Treponema pallidum tpp47 DNA in clinical samples of syphilis patients [PDF]

European Journal of Medical Research
Backgrounds To investigate the relationship between the presence of Treponema pallidum DNA in saliva, serum, and cerebrospinal fluid (CSF) in patients with different stages of syphilis.
Yongjun Meng, Ling Yang, Yu Fu, Si Li, Krishna Hamal, Donghua Liu   +5 more
doaj   +2 more sources

NOTES ON THE CULTIVATION OF TREPONEMA PALLIDUM [PDF]

Journal of Experimental Medicine, 1915
We consider themost importantcontribution reported in this paper the fact that Treponema pallidum can be cultivated in fluid media, without the addition of agar, together with tissues sterilized by heat. This forms an excellent method of obtaining mass cultures for luetin preparation and immunological experimentation.
Hans Zinsser, H Zinsser, Zinsser Hans
exaly   +3 more sources

Loop-mediated isothermal amplification assays for the rapid discrimination of Treponema pallidum lineages and subspecies [PDF]

Microbiology Spectrum
Molecular surveillance aimed at identifying the subspecies and lineages of Treponema pallidum is important. Conventional molecular methods for genotyping are effective but are also time-consuming and costly.
Kazuo Imai, Yuki Ohama, Akihiro Sato, Masashi Tanaka, Ryuha Omachi, Keita Takeuchi, Hitomi Mizushina, Shu-ichi Nakayama, Takuya Maeda, Yukihiro Akeda   +9 more
doaj   +2 more sources

Advanced specificity and sensitivity studies relative to a research use only transcription-mediated amplification-based assay for Treponema pallidum RNA detection [PDF]

Journal of Clinical Microbiology
Preliminary experimentation has suggested that a research-use-only real-time transcription-mediated amplification assay for Treponema pallidum (RUO T. pallidum TMA) yields instances of T.
Trinity Krueger, Grace Kadonsky, Elizabeth Thelen, Amanda Zapp, Josephine Moore, Ahmet Muslu, Allan Pillay, Irene A. Stafford, Erik Munson   +8 more
doaj   +2 more sources

Treponema Pallidum: A Forgotten Pathogen With Major Cardiovascular Consequence. [PDF]

JACC Case Rep
Natour SJ, Rabadia SV, Stefanko DP, Fishbein GA, Parikh RV, Hsu JJ.   +5 more
europepmc   +2 more sources

Research progress in syphilis immunity

Pifu-xingbing zhenliaoxue zazhi, 2022
Syphilis is a sexually transmitted disease caused by treponema pallidum infection. It is mainly transmitted through mucous membrane or injured skin.
Ruihua ZHANG, Qianqiu WANG
doaj   +1 more source

Characterization of Treponema pallidum Dissemination in C57BL/6 Mice

Frontiers in Immunology, 2021
The spirochetal pathogen Treponema pallidum causes 5 million new cases of venereal syphilis worldwide each year. One major obstacle to syphilis prevention and treatment is the lack of suitable experimental animal models to study its pathogenesis ...
Simin Lu, Kang Zheng, Jianye Wang, Man Xu, Yafeng Xie, Yafeng Xie, Shuai Yuan, Chuan Wang, Yimou Wu   +8 more
doaj   +1 more source

Phylogeny and antibiotic resistance of Treponema pallidum subsp. pallidum [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2023
The species Treponema pallidum includes 4 subspecies. According to the bioinformatic analysis, the syphilis pathogen T. pallidum subsp. pallidum was probably separated from the causative agents of yaws, bejel, and pinta more than 800 years ago. Its entry
Nosov N.Yu., Obraztsova O.A., Katunin G.L., Plakhova K.I., Solomka V.S.   +4 more
doaj   +1 more source