Results 11 to 20 of about 20,786 (179)

The prevalence and associated factors of among HIV-positive and HIV-negative individuals who attended voluntary counseling and testing center of St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia: A cross-sectional study design

SAGE Open Medicine, 2020
Background: Treponema pallidum and HIV are among the most common public health problems in Ethiopia. These infections are interrelated. Treponema pallidum causes genital ulcer which enhances HIV transmission and complicates HIV by causing severe ulcer ...
Habtamu Weldesenbet, Daniel Asrat, Yimtubezinash Weldeamanuel   +2 more
doaj   +1 more source

Seroprevalence with epidemiological determinants of hepatitis C virus and Treponema pallidum infection in blood donors of a teaching hospital in southwest Punjab, India: A 5-year study

Journal of Family Medicine and Primary Care, 2023
Background: A high seroprevalence of various transfusion-transmitted infections (TTIs) in donated blood is the main safety concern, especially in low- and middle-income countries.
Nidhi Bansal, Anshul Gupta, Tanvir K. Sidhu, Ram Niwas Maharishi, Saurabh Gupta, Arnav K. Roychoudhury   +5 more
doaj   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Crescentic glomerulonephritis associated with syphilis: a case report and review of the literature

Journal of Medical Case Reports, 2023
Background Crescentic glomerulonephritis with syphilis infection is rare, and the mechanism underlying the formation of glomerular capillary wall damage-induced crescent has not been elucidated. Case presentation A 62-year-old Japanese male showed edema,
Akiko Kaiga, Yuka Sato, Haruna Arakawa, Tatemitsu Rai, Akihiro Tojo   +4 more
doaj   +1 more source

Notes on syphilis vaccine development

Frontiers in Immunology, 2022
The quest for a syphilis vaccine to provide protection from infection or disease began not long after the isolation of the first Treponema pallidum subspecies pallidum (T. pallidum) strain in 1912.
Noah Kojima, Kelika A. Konda, Kelika A. Konda, Jeffrey D. Klausner   +3 more
doaj   +1 more source

Syphilis and the host: multi-omic analysis of host cellular responses to Treponema pallidum provides novel insight into syphilis pathogenesis

Frontiers in Microbiology, 2023
IntroductionSyphilis is a chronic, multi-stage infection caused by the extracellular bacterium Treponema pallidum ssp. pallidum. Treponema pallidum widely disseminates through the vasculature, crosses endothelial, blood–brain and placental barriers, and ...
Sean Waugh, Akash Ranasinghe, Alloysius Gomez, Simon Houston, Karen V. Lithgow, Azad Eshghi, Jenna Fleetwood, Kate M. E. Conway, Lisa A. Reynolds, Caroline E. Cameron, Caroline E. Cameron   +10 more
doaj   +1 more source

Multiplex nested polymerase chain reaction for Treponema pallidum using blood is more sensitive than using serum

Universa Medicina, 2018
Background Syphilis is a multistage disease transmitted primarily through sexual intercourse. Nowadays, the polymerase chain reaction (PCR) test for Treponema pallidum has been widely used and is expected to overcome problems in diagnostic tests for ...
Ida Effendi, Yeva Rosana, Andi Yasmon, Wresti Indriatmi   +3 more
doaj   +1 more source

Investigation of syphilis immunology and Treponema pallidum subsp. pallidum biology to improve clinical management and design a broadly protective vaccine: study protocol

BMC Infectious Diseases, 2020
Background The syphilis epidemic continues to cause substantial morbidity and mortality worldwide, particularly in low- and middle-income countries, despite several recent disease control initiatives.
Ethan Osias, Phoebe Hung, Lorenzo Giacani, Chrysovalantis Stafylis, Kelika A. Konda, Silver K. Vargas, E. Michael Reyes-Díaz, W. Scott Comulada, David A. Haake, Austin M. Haynes, Carlos F. Caceres, Jeffrey D. Klausner   +11 more
doaj   +1 more source

Pathogenesis and Immunology of Treponema Pallidum [PDF]

Annual Review of Microbiology, 1981
THE DISEASE ....... ....... ......... .... ... ....... ... ... ... ...... .. 30 PATHOGENESIS ...... ......... ..... ... ........ ........ ...... .... 32 Mucopolysaccharides ... .. ...... 33 Cultured cell receptor ... ... ... 33 Treponemal capsule ..... ......... ...... ....... ......... ..... .. ... ..... ... ... . ..... ..... ..
T J, Fitzgerald, R C, Johnson
openaire   +4 more sources

The molecular epidemiology of Treponema pallidum subspecies pallidum [PDF]

Sexual Health, 2015
Pathogens adapt and evolve in response to pressures exerted by host environments, leading to generation of genetically diverse variants. Treponema pallidum subspecies pallidum displays a substantial amount of interstrain diversity. These variants have been identified in various parts of the world, indicating transmission linkage between geographical ...
Daphne Y, Ma, Lorenzo, Giacani, Arturo, Centurión-Lara   +2 more
openaire   +2 more sources