Results 11 to 20 of about 38,214 (216)

Treponema pallidum protein Tp0136 promotes angiogenesis to facilitate the dissemination of Treponema pallidum [PDF]

Emerging Microbes and Infections
The incompletely eliminated Treponema pallidum (T. pallidum) during primary syphilis chancre infection can result in the progression of secondary, tertiary, or latent syphilis in individuals, suggesting that T. pallidum has successfully evaded the immune
Tian-Ci Yang
exaly   +4 more sources

Genomic Analysis of Doxycycline Resistance–Associated 16S rRNA Mutations in Treponema pallidum Subspecies pallidum [PDF]

Emerging Infectious Diseases
We inspected 16S rRNA sequences of 784 publicly available Treponema pallidum subspecies pallidum genomes and 17 new T. pallidum subsp. pallidum genomes from Canada for putative mutations associated with doxycycline resistance.
George S. Long, Mackenzie Neale, Thomas Braukmann, Vanessa Tran, Nishant Singh, Vanessa Allen, Muhammad Morshed, Jessica Minion, Paul Van Caeseele, Maud Vallée, Todd Hatchette, Samir N. Patel, Raymond S.W. Tsang, Venkata R. Duvvuri   +13 more
doaj   +2 more sources

Detection of Treponema pallidum tpp47 DNA in clinical samples of syphilis patients [PDF]

European Journal of Medical Research
Backgrounds To investigate the relationship between the presence of Treponema pallidum DNA in saliva, serum, and cerebrospinal fluid (CSF) in patients with different stages of syphilis.
Yongjun Meng, Ling Yang, Yu Fu, Si Li, Krishna Hamal, Donghua Liu   +5 more
doaj   +2 more sources

Whole genome sequence of the Treponema Fribourg-Blanc: unspecified simian isolate is highly similar to the yaws subspecies. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND:Unclassified simian strain Treponema Fribourg-Blanc was isolated in 1966 from baboons (Papio cynocephalus) in West Africa. This strain was morphologically indistinguishable from T. pallidum ssp. pallidum or ssp.
Marie Zobaníková, Michal Strouhal, Lenka Mikalová, Darina Cejková, Lenka Ambrožová, Petra Pospíšilová, Lucinda L Fulton, Lei Chen, Erica Sodergren, George M Weinstock, David Smajs   +10 more
doaj   +6 more sources

Loop-mediated isothermal amplification assays for the rapid discrimination of Treponema pallidum lineages and subspecies [PDF]

Microbiology Spectrum
Molecular surveillance aimed at identifying the subspecies and lineages of Treponema pallidum is important. Conventional molecular methods for genotyping are effective but are also time-consuming and costly.
Kazuo Imai, Yuki Ohama, Akihiro Sato, Masashi Tanaka, Ryuha Omachi, Keita Takeuchi, Hitomi Mizushina, Shu-ichi Nakayama, Takuya Maeda, Yukihiro Akeda   +9 more
doaj   +2 more sources

Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen [PDF]

Nature Reviews Microbiology, 2016
The past two decades have seen a worldwide resurgence in infections caused by Treponema pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity of the syphilis spirochete for early dissemination and immune evasion has earned it ...
David Šmajs, X Frank Yang, Michael Norgard   +2 more
exaly   +3 more sources

Advanced specificity and sensitivity studies relative to a research use only transcription-mediated amplification-based assay for Treponema pallidum RNA detection [PDF]

Journal of Clinical Microbiology
Preliminary experimentation has suggested that a research-use-only real-time transcription-mediated amplification assay for Treponema pallidum (RUO T. pallidum TMA) yields instances of T.
Trinity Krueger, Grace Kadonsky, Elizabeth Thelen, Amanda Zapp, Josephine Moore, Ahmet Muslu, Allan Pillay, Irene A. Stafford, Erik Munson   +8 more
doaj   +2 more sources

Treponema Pallidum: A Forgotten Pathogen With Major Cardiovascular Consequence. [PDF]

JACC Case Rep
Natour SJ, Rabadia SV, Stefanko DP, Fishbein GA, Parikh RV, Hsu JJ.   +5 more
europepmc   +2 more sources

Research progress in syphilis immunity

Pifu-xingbing zhenliaoxue zazhi, 2022
Syphilis is a sexually transmitted disease caused by treponema pallidum infection. It is mainly transmitted through mucous membrane or injured skin.
Ruihua ZHANG, Qianqiu WANG
doaj   +1 more source

Characterization of Treponema pallidum Dissemination in C57BL/6 Mice

Frontiers in Immunology, 2021
The spirochetal pathogen Treponema pallidum causes 5 million new cases of venereal syphilis worldwide each year. One major obstacle to syphilis prevention and treatment is the lack of suitable experimental animal models to study its pathogenesis ...
Simin Lu, Kang Zheng, Jianye Wang, Man Xu, Yafeng Xie, Yafeng Xie, Shuai Yuan, Chuan Wang, Yimou Wu   +8 more
doaj   +1 more source