Results 41 to 50 of about 46,044 (219)

Cultivation of Treponema Pallidum [PDF]

The American Journal of the Medical Sciences, 1911
n ...
openaire   +1 more source

Parameters Affecting Continuous In Vitro Culture of Treponema pallidum Strains

mBio, 2021
Syphilis is caused by the bacterium Treponema pallidum subsp. pallidum. Until recently, this pathogen could only be maintained through infection of rabbits or other animals, making study of this important human pathogen challenging and costly.
D. Edmondson, B. DeLay, Lindsay E. Kowis, S. Norris   +3 more
semanticscholar   +1 more source

Ancient genomes reveal a deep history of Treponema pallidum in the Americas. [PDF]

Nature
Human treponemal infections are caused by a family of closely related Treponema pallidum that give rise to the diseases yaws, bejel, pinta and, most notably, syphilis1.
Barquera R, Sitter TL, Kirkpatrick CL, Ramirez DA, Kocher A, Spyrou MA, Couoh LR, Talavera-González JA, Castro M, von Hunnius T, Guevara EK, Hamilton WD, Roberts P, Scott E, Fabra M, Da Peña GV, Pacheco A, Rodriguez M, Aspillaga E, Tiliakou A, Nelson EA, Giffin KL, Bianco RA, Rohrlach AB, de Los Ángeles García Martínez M, Ballesteros Solís FA, Sajantila A, Saunders SR, Nores R, Herbig A, Krause J, Bos KI.   +31 more
europepmc   +2 more sources

Longitudinal TprK profiling of in vivo and in vitro-propagated Treponema pallidum subsp. pallidum reveals accumulation of antigenic variants in absence of immune pressure

PLoS Neglected Tropical Diseases, 2021
Immune evasion by Treponema pallidum subspecies pallidum (T. pallidum) has been attributed to antigenic variation of its putative outer-membrane protein TprK.
Michelle J. Lin, Austin M Haynes, A. Addetia, N. Lieberman, Q. Phung, Hong Xie, Tien V. Nguyen, B. Molini, S. Lukehart, L. Giacani, A. Greninger   +10 more
semanticscholar   +1 more source

Pathogenesis and Immunology of Treponema Pallidum [PDF]

Annual Review of Microbiology, 1981
THE DISEASE ....... ....... ......... .... ... ....... ... ... ... ...... .. 30 PATHOGENESIS ...... ......... ..... ... ........ ........ ...... .... 32 Mucopolysaccharides ... .. ...... 33 Cultured cell receptor ... ... ... 33 Treponemal capsule ..... ......... ...... ....... ......... ..... .. ... ..... ... ... . ..... ..... ..
T J, Fitzgerald, R C, Johnson
openaire   +4 more sources

The molecular epidemiology of Treponema pallidum subspecies pallidum [PDF]

Sexual Health, 2015
Pathogens adapt and evolve in response to pressures exerted by host environments, leading to generation of genetically diverse variants. Treponema pallidum subspecies pallidum displays a substantial amount of interstrain diversity. These variants have been identified in various parts of the world, indicating transmission linkage between geographical ...
Daphne Y, Ma, Lorenzo, Giacani, Arturo, Centurión-Lara   +2 more
openaire   +2 more sources

Comparison of transcriptional profiles of Treponema pallidum during experimental infection of rabbits and in vitro culture: Highly similar, yet different

PLoS Pathogens, 2021
Treponema pallidum ssp. pallidum, the causative agent of syphilis, can now be cultured continuously in vitro utilizing a tissue culture system, and the multiplication rates are similar to those obtained in experimental infection of rabbits. In this study,
Bridget D De Lay, T. A. Cameron, Nicholas R. De Lay, S. Norris, D. Edmondson   +4 more
semanticscholar   +1 more source

Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up

Data in Brief, 2018
The data presented in this article are related to the research article entitled “Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination”.
Wen Liu, Xiaohong Zhang, Tie Zhao, Chenglong Zhou, Junxia Duan, Feijun Zhao   +5 more
doaj   +1 more source

Glucose incorporation by Treponema pallidum [PDF]

Infection and Immunity, 1979
Treponema pallidum incorporated glucose into trichloroacetic acid-precipitable material. The amount of incorporation was proportional to the number of treponemes and was estimated to equal 3% of the glucose oxidized.
J T, Barbieri, C D, Cox
openaire   +2 more sources

Treponema pallidum Disrupts VE-Cadherin Intercellular Junctions and Traverses Endothelial Barriers Using a Cholesterol-Dependent Mechanism

Frontiers in Microbiology, 2021
Treponema pallidum subspecies pallidum, the causative agent of syphilis, traverses the vascular endothelium to gain access to underlying tissue sites. Herein, we investigate the mechanisms associated with T.
K. Lithgow, E. Tsao, E. Schovanek, Alloysius Gomez, L. A. Swayne, C. Cameron   +5 more
semanticscholar   +1 more source