Results 51 to 60 of about 46,044 (219)

Selective Whole-Genome Amplification as a Tool to Enrich Specimens with Low Treponema pallidum Genomic DNA Copies for Whole-Genome Sequencing

bioRxiv, 2021
Syphilis is a sexually transmitted, disseminated acute and chronic infection caused by the bacterial pathogen Treponema pallidum subspecies pallidum. Primary syphilis typically presents as single or multiple mucocutaneous lesions and, if left untreated ...
Charles M. Thurlow, S. Joseph, L. Ganova-Raeva, Samantha S. Katz, Lara E Pereira, C. Chen, A. Debra, K. Vilfort, K. Workowski, S. Cohen, H. Reno, Yongcheng Sun, Mark Burroughs, M. Sheth, K. Chi, Damien C. Danavall, S. Philip, W. Cao, E. Kersh, A. Pillay   +19 more
semanticscholar   +1 more source

An unusual giant serpiginous lesion of secondary syphilis [PDF]

Anais Brasileiros de Dermatologia, 2018
: Syphilis is a worldwide sexually transmitted infection caused by Treponema pallidum subspecies pallidum. Its association with other STIs, including HIV, demands early diagnosis and immediate treatment of patients.
Xavier Grimaux, Rida El Ayoubi, Christian Le Clec’h   +2 more
doaj   +1 more source

Efficacy of linezolid on Treponema pallidum, the syphilis agent: A preclinical study

EBioMedicine, 2021
Background Penicillin G, the current standard treatment for syphilis, has important drawbacks, but virtually no preclinical or clinical studies have been performed to identify viable alternatives.
Austin M Haynes, L. Giacani, M. V. Mayans, Maria Ubals, C. Nieto, C. Pérez-Mañá, L. Quintó, E. Romeis, O. Mitjà   +8 more
semanticscholar   +1 more source

Complete genome sequence of Treponema paraluiscuniculi, strain Cuniculi A: the loss of infectivity to humans is associated with genome decay.

PLoS ONE, 2011
Treponema paraluiscuniculi is the causative agent of rabbit venereal spirochetosis. It is not infectious to humans, although its genome structure is very closely related to other pathogenic Treponema species including Treponema pallidum subspecies ...
David Šmajs, Marie Zobaníková, Michal Strouhal, Darina Čejková, Shannon Dugan-Rocha, Petra Pospíšilová, Steven J Norris, Tom Albert, Xiang Qin, Kym Hallsworth-Pepin, Christian Buhay, Donna M Muzny, Lei Chen, Richard A Gibbs, George M Weinstock   +14 more
doaj   +1 more source

Analytical Performance Characteristics of a New Transcription-Mediated Amplification Assay for Treponema pallidum

Journal of Clinical Microbiology, 2021
This study evaluated the performance characteristics of a new research-use-only transcription-mediated amplification (TMA) assay for the detection of rRNA from Treponema pallidum.
D. Getman, Mike Lin, N. Barakat, R. Skvoretz, C. Godornes, P. Swenson, Ashley Nenninger, M. Golden, S. Lukehart   +8 more
semanticscholar   +1 more source

In Vitro Antimicrobial Susceptibility of Treponema Pallidum Subsp. Pallidum, the Syphilis Agent

Social Science Research Network, 2022
CA
L. Tantalo, N. Lieberman, C. Pérez-Mañá, M. Vall Mayans, Maria Ubals, C. González-Beiras, A. Rodríguez-Gascón, A. Canut, Alexander L Greninger, L. Giacani, O. Mitjà   +10 more
semanticscholar   +1 more source

Whole genome sequence of the Treponema Fribourg-Blanc: unspecified simian isolate is highly similar to the yaws subspecies. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND:Unclassified simian strain Treponema Fribourg-Blanc was isolated in 1966 from baboons (Papio cynocephalus) in West Africa. This strain was morphologically indistinguishable from T. pallidum ssp. pallidum or ssp.
Marie Zobaníková, Michal Strouhal, Lenka Mikalová, Darina Cejková, Lenka Ambrožová, Petra Pospíšilová, Lucinda L Fulton, Lei Chen, Erica Sodergren, George M Weinstock, David Smajs   +10 more
doaj   +1 more source

Pyruvate oxidation by Treponema pallidum [PDF]

Infection and Immunity, 1979
Cell-free extracts of Treponema pallidum catalyzed the decarboxylation of pyruvate. This activity was suppressed at low O2 tensions and appeared to be coenzyme A independent. Pyruvate decarboxylation was inorganic phosphate dependent, and evidence suggested that acetyl phosphate was a product.
J T, Barbieri, C D, Cox
openaire   +2 more sources

High rates of Treponema pallidum, Neisseria gonorrhoeae, Chlamydia trachomatis, or Trichomonas vaginalis co-infection in people with HIV: a systematic review and meta-analysis

European Journal of Clinical Microbiology and Infectious Diseases
People living with HIV (PWH) experience a disproportionate burden of sexually transmitted infections (STIs), leading to more severe health outcomes and increasing the risk of HIV transmission.
Qinyi Zhang, Lin Peng, Yuan Yuan, Zongnan Hu, Ying Zeng, Weijia Zeng, Jiaxin Chen, Wenxin Chen, Peng Liu   +8 more
semanticscholar   +1 more source

Neurosyphilis with a rare magnetic resonance imaging pattern confirmed by metagenomic next-generation sequencing: a case report

European Journal of Medical Research, 2022
Background Neurosyphilis refers to infection of the central nervous system by Treponema pallidum. The clinical presentation is variable and nonspecific.
Chang Liu, Yu Zhang, Yi Li, Hui Bu, Ruoxue Liu, Yingxiao Ji, Junying He, Kun Hong   +7 more
doaj   +1 more source