Results 71 to 80 of about 22,162 (180)

Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages

Nature Communications, 2019
Syphilis is caused by the bacterium Treponema pallidum subspecies pallidum (TPA), and incidence has risen recently in many countries. Here, Beale et al.
Mathew A. Beale, Michael Marks, Sharon K. Sahi, Lauren C. Tantalo, Achyuta V. Nori, Patrick French, Sheila A. Lukehart, Christina M. Marra, Nicholas R. Thomson   +8 more
doaj   +1 more source

Neurosyphilis Concurrently Presenting With Limbic Encephalitis and Normal Pressure Hydrocephalus: A Case Report

Neuropsychopharmacology Reports, Volume 46, Issue 4, December 2026.
We report a case of neurosyphilis characterized by early‐onset dementia, limbic encephalitis, and normal pressure hydrocephalus. Psychiatrists should be aware of the possibility of neurosyphilis in such cases. ABSTRACT Background Neurosyphilis may present with a variety of clinical symptoms and neuroimaging findings and is thus likely to be overlooked.
Naoki Obata, Kenshi Terajima, Gen Miura, Yuta Muratake, Shun Irie, Yuichiro Watanabe   +5 more
wiley   +1 more source

Steadiness of treponema pallidum to changes of optimum conditions of cultivacion

RUDN Journal of Medicine, 2010
By the time of discovery of the causative agent of syphilis by F. Schaudinn and E. Hoffmann (1905г.) the illness itself was spread for more than 400 years. Even after R.
A Ch Kaziev
doaj  

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, Volume 73, Issue 5, Page 2457-2481, October 2026.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Implementation of a molecular assay for Treponema pallidum detection in the management of syphilis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Valeria Gaspari, Greta Roncarati, Tiziana Lazzarotto, Claudio Foschi, Antonella Marangoni   +4 more
wiley   +1 more source

Pharmacokinetic and Pharmacodynamic Drug‐Drug Interactions Between Cofrogliptin and Metformin in Healthy Subjects: A Single‐Center, Single‐Arm, Phase I Study in China

Clinical Pharmacology in Drug Development, Volume 15, Issue 10, October 2026.
Abstract This single‐center, single‐arm, Phase I study evaluated drug–drug interactions (DDIs) between cofrogliptin and metformin in healthy Chinese subjects. Twenty‐two subjects sequentially received metformin monotherapy (Days 1–4), cofrogliptin monotherapy (Days 6–34), and combination therapy (Days 38–47).
Cheng Cui, Na Liu, Chang Chu, Shu Niu, Yang Huang, Fangqiong Li, Yaming Li, Haiyan Li, Dongyang Liu   +8 more
wiley   +1 more source

Role of disorders related to idiotypic and anti-idiotypic interactions in slowing down the achievement of negative serologic reactions in patients with early onset forms of syphilis after specific therapy

Vestnik Dermatologii i Venerologii, 2017
Goal. To study the humoral immunity state in patients with the slowed down achievement of negative serologic reactions after the treatment of early onset forms of syphilis by means of examining the blood serum level of idiotypic and anti-idiotypic ...
YE. N. Volkova, S. G. Morozov, YE. V. Mitichkina, A. A. Grigoriyeva, I. V. Yelistratova   +4 more
doaj   +1 more source

Blood Unit Discard Rates Due to Transfusion–Transmissible Infections and Non‐Infectious Causes and Their Associated Factors in Eastern and Northeastern Parts of Amhara Regional State, Ethiopia: A Retrospective Cross‐Sectional Study From 2022–2025

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Blood is an irreplaceable medical resource, yet blood unit discard remains a significant challenge for transfusion services. This study aimed to evaluate discard rates by integrating both infectious (TTI) and non‐infectious causes and identifying factors associated with blood wastage to provide evidence to support strategies for ...
Tesfaye Gessese, Afewerk Habtamu Aseme, Zewudu Mulatie, Mikiyas Shemelis Achame, Sisay Desale, Saleamlak Sebsibe, Yonas Erkihun, Yeshimebet Kassa, Mahider Shimelis Feyisa, Mihreteab Alebachew, Bruktawit Eshetu, Tadesse Sisay   +11 more
wiley   +1 more source

Rare Case of Four Osseous Lesions of the Skull in a Patient with Secondary Syphilis

Case Reports in Infectious Diseases, 2018
Syphilis is a sexually transmitted infection that is caused by the bacterium Treponema pallidum. Syphilis can present as primary, secondary, tertiary, or congenital.
Jace Kusler, Supha Arthurs
doaj   +1 more source

Cytogenetic and Molecular Findings in Hydrops‐Related Mirror Syndrome

Prenatal Diagnosis, Volume 46, Issue 11, Page 1752-1759, October 2026.
ABSTRACT Objective Mirror syndrome is a rare, life‐threatening condition in which maternal fluid overload mirrors fetal hydrops. Data on genetic findings in affected pregnancies are limited. We compared genetic diagnoses in hydrops cases with and without mirror syndrome.
Brian A. Burnett, Christian M. Parobek, Jessian L. Munoz, Lauren E. Westerfield, Kristi Poling, Cara Buskmiller, Amir A. Shamshirsaz, Roopali V. Donepudi, Ignatia B. Van den Veyver, Magdalena Sanz Cortes, Michael A. Belfort, Ahmed A. Nassr   +11 more
wiley   +1 more source