Results 61 to 70 of about 46,044 (219)

Progress on the methods for detection of and study on Treponema pallidum

Pifu-xingbing zhenliaoxue zazhi
The traditional methods for Treponema pallidum detection are limited due to the lack of convenience and sensitivity, which affect its application in the early diagnosis of syphilis.
Ligang YANG
doaj   +1 more source

The Treponema pallidum Outer Membrane [PDF]

, 2017
The outer membrane (OM) of Treponema pallidum, the uncultivatable agent of venereal syphilis, has long been the subject of misconceptions and controversy. Decades ago, researchers postulated that T. pallidum's poor surface antigenicity is the basis for its ability to cause persistent infection, but they mistakenly attributed this enigmatic property to ...
Justin D, Radolf, Sanjiv, Kumar
openaire   +2 more sources

Há 100 anos, a descoberta do Treponema pallidum A hundred years ago, the discovery of Treponema pallidum

Anais Brasileiros de Dermatologia, 2005
A descoberta do Treponema pallidum por Schaudinn & Hoffmann em 3 de março de 1905 foi influenciada pela comunicação de Siegel, sobre a descoberta do agente etiológico da sífilis.
Elemir Macedo de Souza
doaj   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Diagnóstico de Sífilis a Partir de Lesões da Mucosa Oral

Acta Médica Portuguesa, 2014
Palavras-chave: Doenças da Boca; Sífilis; Sífilis Cutânea; Treponema pallidum.
Luis Uva, João Borges-Costa, Paulo Filipe   +2 more
doaj   +1 more source

Ancient Bacterial Genomes Reveal a High Diversity of Treponema pallidum Strains in Early Modern Europe.

Current Biology, 2020
Syphilis is a globally re-emerging disease, which has marked European history with a devastating epidemic at the end of the 15th century. Together with non-venereal treponemal diseases, like bejel and yaws, which are found today in subtropical and ...
K. Majander, S. Pfrengle, Arthur Kocher, Judith Neukamm, L. du Plessis, M. Pla-Díaz, N. Arora, Gülfirde Akgül, K. Salo, R. Schats, S. Inskip, M. Oinonen, H. Valk, Martin Malve, A. Kriiska, P. Onkamo, F. González-Candelas, D. Kühnert, J. Krause, V. Schuenemann   +19 more
semanticscholar   +1 more source

Canadian Public Health Laboratory Network Laboratory Guidelines for the Use of Direct Tests to Detect Syphilis in Canada

Canadian Journal of Infectious Diseases and Medical Microbiology, 2015
Treponema pallidum subsp. pallidum and/or its nucleic acid can be detected by various methods such as microscopy, rabbit infectivity test or polymerase chain reaction (PCR) tests. The rabbit infectivity test for T.
Raymond SW Tsang, Muhammad Morshed, Max A Chernesky, Gayatri C Jayaraman, Kamran Kadkhoda   +4 more
doaj   +1 more source

Juvenile Gangrenous Vasculitis of the Scrotum or Scrotum Lipschütz Ulcers

JEADV Clinical Practice, EarlyView.
ABSTRACT Lipschütz genital ulcers are traditionally described in adolescent females and often linked to acute viral infections. Their male counterpart remains poorly characterised. We report a 59‐year‐old man with sudden onset of unilateral necrotic ulcers on the scrotum and inguinal region following a brief febrile episode and mild pharyngitis ...
Francesco Bellinato, Paolo Gisondi, Giampiero Girolomoni   +2 more
wiley   +1 more source

A New Specimen for Syphilis Diagnosis: Evidence by High Loads of Treponema pallidum DNA in Saliva

Clinical Infectious Diseases, 2020
Background DNA from many pathogens can be detected in saliva. However, the presence and quantity of Treponema pallidum DNA in patients with syphilis in saliva is unknown.
Cuini Wang, Zhixiang Hu, Xin Zheng, M. Ye, Chunjie Liao, Mengya Shang, Weiming Gong, Z. Guan, Haikong Lu, X. Gu, Mei Shi, P. Zhou   +11 more
semanticscholar   +1 more source

Detection of Treponema pallidum subspecies pallidum for the diagnosis of congenital syphilis by nested polymerase chain reaction

Biomédica: revista del Instituto Nacional de Salud, 2018
Introduction. Syphilis is a disease produced by Treponema pallidum subspecies pallidum, which affects approximately 12 million people worldwide every year.
Gladys Pinilla, Lesly Campos, Andrea Durán, Jeannette Navarrete, Liliana Muñoz   +4 more
doaj   +1 more source