Results 21 to 30 of about 6,963 (223)

Clinical trial protocol to evaluate the efficacy of cefixime in the treatment of early syphilis

Trials, 2020
Background Syphilis rates have been increasing both in the USA and internationally with incidence higher among men-who-have-sex-with-men and people living with human immunodeficiency virus (HIV) infection.
Shivani N. Mehta, Chrysovalantis Stafylis, David M. Tellalian, Pamela L. Burian, Cliff M. Okada, Carl E. Millner, Christopher M. Mejia, Jeffrey D. Klausner   +7 more
doaj   +1 more source

UK National Audit of Early Syphilis Management. Clinics audit: screening for and management of early syphilis [PDF]

, 2006
Data were provided by 131 clinics, and 56% of cases were managed in clinics in the London regions in 2003. Three clinics (2%) do not routinely screen new patients for syphilis, and 28 clinics (21%) do not routinely screen ‘rebook’ patients who have ...
Bunting, P, Carne, C, Daniels, D, McClean, H, Miller, R   +4 more
core   +1 more source

A Rare Case of Neurosyphilis with Calvaria Osteitis Presenting in Pregnancy

Case Reports in Obstetrics and Gynecology, 2023
Background. The incidence of syphilis throughout the world is increasing. Rates in pregnancy are similarly rising, presenting risks of an untreated syphilis infection that can be detrimental to the mother and fetus.
Gisella M. Newbery, Christine E. Henricks, Julie A. Vircks, Andreina Colina, David C. Mundy   +4 more
doaj   +1 more source

UK National Audit of Early Syphilis Management. Case notes audit: diagnosis and treatment [PDF]

, 2006
A national audit of 781 early syphilis cases presenting during 2002–03 in UK genitourinary medicine clinics was conducted in late 2004, organized through the Regional Audit Groups.
Bunting, P, Carne, C, Daniels, D, McClean, H, Miller, R   +4 more
core   +1 more source

Early syphilis: serological treatment response to doxycycline/tetracycline versus benzathine penicillin

Journal of Infection in Developing Countries, 2014
Introduction: Benzathine penicillin G is the treatment of choice for syphilis, but doxycycline and tetracycline are effective second-line treatments. The objective of this study was to assess the serological response to treatment for early syphilis with ...
Jun Li, He-Yi Zheng
doaj   +1 more source

Kounis syndrome associated with benzathine penicillin G use: A case report

Dermatologica Sinica, 2013
Kounis syndrome is a life-threatening medical condition that causes severe allergic reaction and acute coronary syndrome. Benzathine penicillin G is one of the most widely used antibiotics in clinical practice, but it can enhance both allergic and ...
Arif Duran, Tarık Ocak, Serkan Öztürk, Nadir Goksugur   +3 more
doaj   +1 more source

Antenatal syphilis screening in sub-Saharan Africa: lessons learned from Tanzania. [PDF]

, 2005
UNLABELLED: OBJECTIVES; To synthesise data from four recent studies in Tanzania examining maternal syphilis screening and its operational implementation in routine antenatal clinics (ANC), drawing lessons for strengthened antenatal services for the ...
Changalucha, John, Gavyole, Awene, Gumodoka, Balthazar, Hayes, Richard, Kumaranayake, Lilani, Mabey, David, Mayaud, Philippe, Oliff, Monique, Semakafu, Ave Maria, Terris-Prestholt, Fern, Watson-Jones, Deborah   +10 more
core   +1 more source

Prolonged benzathine penicillin G improves long-term serological outcomes in HIV-negative neurosyphilis: a multicenter study exploring prognostic factors and therapeutic outcomes

International Journal of Infectious Diseases
Objectives: Neurosyphilis is a serious complication of Treponema pallidum infection. Some patients experience relapse or serofast response despite standard intravenous penicillin G. While adjunctive benzathine penicillin is recommended in some guidelines,
Beilin Luo, Ting Wang, Shiyong Li, Nengsheng Wu, Nan Sheng, Shunpo He, Qingwei Yang   +6 more
doaj   +1 more source

Longitudinal Variations in the tprK Gene of Treponema pallidum in an Amoy Strain-Infected Rabbit Model

Microbiology Spectrum, 2023
Heterogeneous tprK sequences have been hypothesized to be an important factor for persistent infection of Treponema pallidum subsp. pallidum (T. pallidum) in humans.
Dan Liu, Rui Chen, Yun He, Yong-jing Wang, Li-Rong Lin, Li-Li Liu, Tian-Ci Yang, Man-Li Tong   +7 more
doaj   +1 more source

Impact of antiretroviral therapy on adult HIV prevalence in a low-income rural setting in Uganda: a longitudinal population-based study.

, 2013
OBJECTIVE: To estimate the contribution to HIV prevalence of lives saved due to the introduction of antiretroviral therapy (ART) in rural Uganda in 2004. DESIGN: Open population-based cohort study.
Maher, Dermot, Nsubuga, Rebecca N, Todd, Jim E   +2 more
core   +1 more source