Results 31 to 40 of about 4,330 (174)

Clinical Outcome Associated With Beta‐Lactam Allergy Labels in Hospitalized Patients in Belgium

Clinical and Translational Allergy, Volume 16, Issue 4, April 2026.
ABSTRACT Background In the United States, beta‐lactam allergy labels (BLAL) are documented in 9%–16% of hospitalized patients and associated with worse clinical outcomes such as increased mortality, length of hospital stay (LOS), intensive care unit (ICU) admission, and use of alternative antibiotics, providing an incentive for broad delabeling ...
Liesbeth Gilissen, Greet Van De Sijpe, Annouschka Laenen, Peter Declercq, Dries Wets, Ileana Ghiordanescu, Anca Mirela Chiriac, Willy E. Peetermans, Paul De Munter, Isabel Spriet, Rik Schrijvers   +10 more
wiley   +1 more source

Genetic Susceptibility to Rheumatic Heart Disease: A Narrative Literature Review Highlighting Evidence From African Populations and Research Gaps in Sudan

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Rheumatic heart disease (RHD) remains a significant public health burden in low‐ and middle‐income countries, particularly in sub‐Saharan Africa. Although socioeconomic factors contribute to disease persistence, genetic susceptibility plays a critical role in determining progression from Group A Streptococcal infection to ...
Hussam Alkhalifamohamed, Waleed M. A. Jebreel, Mohamed Elhassan, Sulafa K. M. Ali   +3 more
wiley   +1 more source

Comparative Study of Oral Daily Amoxicillin, Long Acting Intramuscular Penicillin, and Tonsillectomy in Prevention of Recurrent Pharyngitis

Medicine Science, 2015
Pediatric recurrent pharyngitis represents a huge global health burden causing much morbidity and mortality in children. The aim of the study was to compare the efficacy of oral daily amoxicillin, intramuscular penicillin, and tonsillectomy in reducing ...
Amira S Ahmed, Engy A Wahsh, Essam Eldin G. Ahmed   +2 more
doaj   +1 more source

Progress towards the elimination of vertical transmission of HIV, syphilis and hepatitis B in 21 high‐burden countries

Journal of the International AIDS Society, Volume 29, Issue 4, April 2026.
Abstract Introduction Elimination of mother‐to‐child transmission (EMTCT) of HIV, syphilis and hepatitis B by 2030 is a global goal endorsed by countries. To achieve EMTCT, countries need to meet targets for programme and impact indicators. Methods We examined progress and gaps in service delivery across the three infections among 21 countries with a ...
Melanie M. Taylor, Rania A. Tohme, Robert McDonald, Michele Montandon   +3 more
wiley   +1 more source

Case Report: Detection of Treponema phagedenis in cerebrospinal fluid of a neurosyphilis patient by metagenomic next-generation sequencing

Frontiers in Cellular and Infection Microbiology, 2023
Treponema phagedenis, a human commensal spirochete, has been reported world-wide as a key factor in the pathogenesis of bovine digital dermatitis. Here we report a case of T.
Chenyan Yuan, Chenyan Yuan, Wei Xu, Wei Xu, Chenggui Zhao, Chenggui Zhao, Wei Gao, Wei Gao, Guoqiu Wu, Guoqiu Wu, Guoqiu Wu   +10 more
doaj   +1 more source

α‐Adrenergic blockade impairs ductus venosus shunting during an acute period of fetal hypoxaemia without further deficits to cerebral oxygen delivery

Experimental Physiology, Volume 111, Issue 4, Page 1796-1807, 1 April 2026.
Abstract The fetal circulation has unique shunts, including the ductus venosus (DV), the tone of which dictates how much substrate‐rich blood returning from the placenta is streamed preferentially away from the liver and instead towards the heart. Herein, we aimed to use clinically relevant MRI techniques in sheep to measure indirectly induced changes ...
Jack R. T. Darby, Stacey L. Holman, Brahmdeep S. Saini, Sunthara Rajan Perumal, Mike Seed, Christopher K. Macgowan, Janna L. Morrison   +6 more
wiley   +1 more source

Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment Failure

Case Reports in Obstetrics and Gynecology, 2018
We report a case of early latent syphilis (reactive serologic tests without clinical evidence of disease within 24 months from the onset of the infection) in pregnancy.
Lucia Pasquini, Elena Rita Magro-Malosso, Adalgisa Cordisco, Michele Trotta, Mariarosaria Di Tommaso   +4 more
doaj   +1 more source

Methodological comparison of fetal brain 1H‐MRS data analysis techniques and gestational age analysis using LCModel in the fetal sheep brain

Experimental Physiology, Volume 111, Issue 4, Page 1597-1611, 1 April 2026.
Abstract Proton (1H) magnetic resonance spectroscopy (MRS) is a non‐invasive imaging technique that can be used to assess brain metabolism. Establishing reference levels of fetal brain metabolites in a translatable preclinical model is crucial for identifying subtle deviations from normal cerebral development. Herein, we developed a 1H‐MRS protocol for
Jordan A. Minns, Jack R. T. Darby, Georgia K. Williams, Jesse T. Tu, Ziqi Sun, Jessie Guo, Steven P. Miller, Christopher K. Macgowan, Mike Seed, Jamie Near, Janna L. Morrison   +10 more
wiley   +1 more source

Low syphilis treatment rates and associated birth outcomes in pregnant women with and without HIV in Zambia: A cohort study

International Journal of Gynecology &Obstetrics, Volume 172, Issue 3, Page 1569-1575, March 2026.
Abstract Objective Syphilis and HIV in pregnancy contribute to adverse birth outcomes in Africa. Benzathine penicillin G remains an effective treatment for syphilis in pregnancy, yet gaps persist in timely treatment. The aim of this study was to compare factors associated with adverse birth outcomes among pregnant women diagnosed with syphilis in ...
Albert Manasyan, Anna V. Jones, Yumo Xue, Herbert Kapesa, Maureen Mzumara, Jodie A. Dionne, Mwangelwa Mubiana‐Mbewe   +6 more
wiley   +1 more source

Fatal and Near-Fatal Non-allergic Reactions in Patients with Underlying Cardiac Disease Receiving Benzathine Penicillin G in Israel and Switzerland

Frontiers in Pharmacology, 2017
Benzathine Penicillin G (BPG) is commonly used for treatment of penicillin-susceptible infections and secondary prevention of rheumatic fever. Death following administration of BPG is extremely rare—only a handful of cases have been described in the ...
Matitiahu Berkovitch, Matitiahu Berkovitch, Liat Ashkenazi-Hoffnung, Liat Ashkenazi-Hoffnung, Ilan Youngster, Ilan Youngster, Dotan Shaniv, Dotan Shaniv, Dorit Dil-Nahlieli, Einat Gorelik, Martina Schäublin, Rudolf Stoller, Nour Karra, Nour Karra, Eyal Schwartzberg, Eyal Schwartzberg   +15 more
doaj   +1 more source