Results 131 to 140 of about 3,116 (182)

Electrochemical oxidation of 2,5-dihydro-1h-1-benzazepines : Synthesis of 5H-1-benzazepines

Tetrahedron, 1995
Abstract Formation of 5H-1-benzazepines was observed after electrochemical oxidation of the title compounds in a flow cell at a graphite felt anode and in acetic buffer. In basic medium, coupling reaction also occurs leading to [2,5-dihydro-1H-1-benzazepin-1-yl]-5H-1-benzazepines. Oxidation mechanisms are discussed.
B. Kharraz, P. Uriac, L. Toupet, J.P. Hurvois, C. Moinet, A. Tallec   +5 more
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Preparation d'hexahydroisoquinoleino [3,2-b] benzazepines-3; transposition en hexahydroisoquinoleino [2,1-b] benzazepines-2

Tetrahedron, 1983
Abstract Pictet-Spengler cyclisation of threo 1-hydroxy-2-(3',4'-methylenedioxybenzyl)-7, 8-dimethoxy-2,3,4,5-tetrahydro-1H 3-benzazepine 2b gives a mixture of diastereoisomers of 14-hydroxy-2,3-dimethoxy-10,11-methylenedioxy-5,6,8,13,13a,14-hexahydroisoquino [3,2-b] 3-benzazepine 3a and 3b .
A. Graftieaux, J. Likforman, J. Gardent
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ChemInform Abstract: 2‐BENZAZEPINES. 7. SYNTHESIS OF PYRIMIDO(5,4‐D)(2)BENZAZEPINES

Chemischer Informationsdienst, 1984
AbstractDas 3‐Phenyl‐phthalid (I) wird mit dem Anion des Acetonitrils zu Hydroxyisobenzofuran (II) umgesetzt.
J. V. EARLEY, R. I. FRYER, N. W. GILMAN
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Regioselective alkylation reactions of 2,4-diphenyl-3H-1-benzazepine give either 3-alkyl-3H-1-benzazepines or 1-alkyl-1H-1-benzazepines

Tetrahedron Letters, 2014
2,4-Diphenyl-3H-1-benzazepine is deprotonated with either LDA or KHMDS. The resulting anion is alkylated with alkyl halides or MeOTs, giving either products of alkylation at C3, or at N, or a mixture of both. The regioselectivity depends on the base, presence of the complexing agent HMPA, and the leaving group of the alkylating agent.
Allen Ko, Aaron Lam, Jeffrey Li, Edyta M. Greer, David J. Szalda, Sasan Karimi, Gopal Subramaniam, Keith Ramig   +7 more
openaire   +1 more source

Synthesis of Dihydro-1-benzazepines

HETEROCYCLES, 2013
A variety of dihydro-1-benzazepines (X) is prepared via a Claisen rearrangement of allyl phenyl ether (III) and a ring-closing metathesis of dienes (IX) as key steps.
Meng-Yang Chang, Chieh-Kai Chan, Shin-Ying Lin   +2 more
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1-Benzazepines. The Synthesis and Reactivity of 2-Chloro-1,5-Dimethyl-1h-1-Benzazepines

Australian Journal of Chemistry, 1986
Treatment of laevulinic acid with N- methylaniline yields 1,5-dimethyl- 1H-1-benzazepin-2(3H)-one and 5-methyl-5-[4-( methylamino )phenyl]-1- phenylpyrrolidin-2-one. The structure of the latter is confirmed by a single-crystal X-ray study. The yield of benzazepinone is increased if either m- methoxy-N-methylaniline or m-methyl-N- methylaniline is ...
JH Bowie, RN Hayes, S Mitkas, RH Prager, MJ Raftery, BW Skelton, MB Stringer, AH White   +7 more
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1,5-Ethano-2,3,4,5-tetrahydro-1H-3-benzazepines

Journal of Medicinal Chemistry, 1975
1,5-Ethano-2,3,4,5-tetrahydro-1H-3-benzazepine, from the LiA1H4 reduction of 2-benzyloxy-1,5-ethano-4-oxo-2,3,4,5-tetrahydro-1H-3-benzazepine, was converted to N-alkyl, aralkyl, cycloalkyl, and alkenyl derivatives which were inactive as morphine type analgetics in mice.
L A, Walter, W K, Chang
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2-Benzazepines. 5. Synthesis of pyrimido[5,4-d][2]benzazepines and their evaluation as anxiolytic agents

Journal of Medicinal Chemistry, 1983
A series of 5H-pyrimido[5,4-d][2]benzazepines has been synthesized, starting from the corresponding 2-benzazepin-5-ones, and evaluated as potential anxiolytic agents. Selected compounds from this series show a pharmacological profile of action different than that of diazepam. They are more potent than diazepam in the anti-pentylenetetrazole test and in
E J, Trybulski, L E, Benjamin, J V, Earley, R I, Fryer, N W, Gilman, E, Reeder, A, Walser, A B, Davidson, W D, Horst, J, Sepinwall   +9 more
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Some derivatives of 1-benzazepine

Canadian Journal of Chemistry, 1969
A new rearrangement of a substituted 5H-1-benzazepine-5-one is described. A new route to certain dimethyl-1-benzazepines has been developed and linked up with a known synthesis. Several new derivatives of 1-benzazepine are reported.
A. H. Rees, K. Simon
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Synthesis and Biological Evaluation of Benzazepine Oxazolidinone Antibacterials.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Paul D, Johnson, Paul A, Aristoff, Gary E, Zurenko, Ronda D, Schaadt, Betty H, Yagi, Charles W, Ford, Judith C, Hamel, Douglas, Stapert, Judy K, Moerman   +8 more
openaire   +2 more sources