Results 21 to 30 of about 167 (133)
International Journal of Molecular Imaging, Volume 2011, Issue 1, 2011., 2011 Disturbances of the cerebral cholinergic neurotransmitter system are present in neurodegenerative disorders. SPECT or PET imaging, using radiotracers that selectively target muscarinic receptor subtypes, may be of value for in vivo evaluation of such conditions.
Remco J. J. Knol +6 more
wiley +1 more source
Strains of Rodents and the Pharmacology of Learning and Memory
Neural Plasticity, Volume 11, Issue 3-4, Page 205-216, 2004., 2004 Mendelian genetic tools have extensively been used to improve the description of the pharmacological mechanisms involved in learning and memory. The first part of this short review describes experiments involving the bidirectional selection of rats or mice for extreme behavioral characteristics or for sensitivity to pharmacological treatments.
Martine Ammassari-Teule +1 more
wiley +1 more source
Berichte der deutschen chemischen Gesellschaft, 1883 n ...
Goldschmidt, Heinrich, Meyer, Victor
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Management of Irritable Bowel Syndrome: Novel Approaches to the Pharmacology of Gut Motility
Canadian Journal of Gastroenterology and Hepatology, Volume 13, Issue A, Page 50A-65A, 1999., 1999 Although it is unclear to what extent irritable bowel syndrome (IBS) symptoms represent a normal perception of abnormal function or an abnormal perception of normal function, many believe that IBS constitutes the clinical expression of an underlying motility disorder, affecting primarily the mid‐ and lower gut.
Carmelo Scarpignato, Iva Pelosini
wiley +1 more source
Journal of Chemistry, Volume 2026, Issue 1, 2026.The novel complex cesium benzilate monohydrate, Cs[C14H11O3]·H2O, was synthesized via the reaction of benzilic acid and cesium carbonate, and high‐purity single crystals were obtained by slow aqueous solvent evaporation. Powder X‐ray diffraction validated the crystalline phase purity.
Gerzon E. Delgado +9 more
wiley +1 more source
Journal of Neurochemistry, Volume 169, Issue 5, May 2025.In Alzheimer's disease, reduced release of ACh is linked more to Aβ pathology than to age‐related change, highlighting an early sign of disease. ABSTRACT A progressive decline in cognitive function occurs as a result of aging and Alzheimer's disease (AD) and is primarily associated with diminished cholinergic neurotransmission.
Itsumi Nagai‐Arakawa +14 more
wiley +1 more source
British Journal of Pharmacology, Volume 181, Issue 22, Page 4385-4398, November 2024.Emerging evidence suggests muscarinic acetylcholine receptors represent novel targets to treat alcohol use disorder. In this review, we draw from literature across medicinal chemistry, molecular biology, addiction and learning/cognition fields to interrogate the proposition for muscarinic receptor ligands in treating various aspects of alcohol use ...
Leigh C. Walker +4 more
wiley +1 more source
The 1990 International Symposium on Laboratory Automation and Robotics
, 1990 Journal of Analytical Methods in Chemistry, Volume 12, Issue 6, Page 227-250, 1990.
Glenn L. Taylor +2 more
wiley +1 more source
Abstracts of the International Symposium on Dementia in Parkinson’s Disease
, 1994 Behavioural Neurology, Volume 7, Issue 1, Page 5-36, 1994.
wiley +1 more source
Benzilic acid: a monoclinic polymorph
IUCrDataThe title compound, C14H12O3, is an α-hydroxycarboxylic acid whose orthorhombic polymorph has been reported earlier [Qiu et al. (2007). Inorg. Chim. Acta, 360, 1819–1824]. The asymmetric unit contains two complete molecules. Classical hydrogen bonds, as well as C—H...O contacts, connect the molecules to infinite chains along the crystallographic c-axis
Petrus Prinsloo +2 more
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