Results 1 to 10 of about 20,324 (99)

Benzo[A]Pyrene and Benzo[E]Pyrene: Photoreactivity and Phototoxicity toward Human Keratinocytes

Photochemistry and Photobiology, 2022
AbstractPolycyclic aromatic hydrocarbons (PAHs) are a group of organic compounds derived mostly from the incomplete combustion of fossil fuels and biomass. Human skin can absorb PAHs and the uptake increases with their molar mass and lipophilicity. Benzopyrene is high molecular weight PAH frequently appearing in ambient pollution.
Krystian Mokrzyński, Grzegorz Szewczyk, Tadeusz Sarna   +2 more
openaire   +3 more sources

Effects of cluster formation on spectra of benzo[a]pyrene and benzo[e]pyrene [PDF]

Chemical Physics Letters, 2008
Absorption and fluorescence emission spectra of the polycyclic aromatic hydrocarbons benzo[a]pyrene (BaP) and benzo[e]pyrene (BeP) in solution and adsorbed on silica have been obtained and compared to examine the spectroscopic effects of clustering. Molecular mechanics calculations with the UFF potential were done to optimize monomer, dimer and trimer ...
Fioressi, Silvina Ethel, Binning, R. C., Bacelo, Daniel Enrique   +2 more
openaire   +3 more sources

Determination of Benzo (a) pyrene in Foods

Journal of AOAC INTERNATIONAL, 1978
Abstract An analytical method was developed for determining benzo (a) pyrene in foods, suitable for routine use. The method consists of 4 cleanup steps: (1) alkali cleavage of sample, (2) preliminary silica gel column chromatography, (3) selective extraction with concentrated sulfuric acid, and (4) further silica gel column ...
Y, Saito, H, Sekita, M, Takeda, M, Uchiyama   +3 more
openaire   +2 more sources

Differential metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 variants [PDF]

Carcinogenesis, 2001
Cytochrome P450 1A1 (CYP1A1) plays a key role in the metabolism of carcinogens, such as benzo[a]pyrene (B[a]P) and metabolites to ultimate carcinogens. Three human allelic variants, namely wild-type (CYP1A1.1), CYP1A1.2 (I462V) and CYP1A1.4 (T461N), were coexpressed by coinfection of baculovirus-infected insect cells with human NADPH-P450 reductase ...
D, Schwarz, P, Kisselev, I, Cascorbi, W H, Schunck, I, Roots   +4 more
openaire   +2 more sources

Metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-diol by human cytochrome P450 1B1 [PDF]

Carcinogenesis, 1998
Benzo[a]pyrene (B[a]P), a ubiquitous environmental, tobacco and dietary carcinogen, has been implicated in human cancer etiology. The role of human cytochrome P450 1B1 in the metabolism of B[a]P is poorly understood. Using microsomal preparations of human P450 1A1, 1A2 and 1B1 expressed in baculovirus-infected insect cells, as well as human and rat ...
J H, Kim, K H, Stansbury, N J, Walker, M A, Trush, P T, Strickland, T R, Sutter   +5 more
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Reactivity with DNA of three pyrenofuran analogues of benzo(a)pyrene and benzo(e)pyrene

Nucleic Acids Research, 1987
Three pyrenofurans, the pyreno[1,2-b]furan (FP1), the pyreno[2,1-b] furan (FP2) and the pyreno[4,5-b]furan (FP3) have been synthesized as analogues of the mutagenic and carcinogenic benzo(a)pyrene (FP1 and FP2) and of its non-carcinogenic isomer benzo(e)pyrene (FP3).
B, Jolles, P, Demerseman, O, Chalvet, H, Strapelias, T, Herning, R, Royer, M, Duquesne   +6 more
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Photolysis primes biodegradation of benzo[a]pyrene [PDF]

Applied and Environmental Microbiology, 1988
14C-labeled benzo[a]pyrene (BaP) was used as a model-compound for polycyclic aromatic hydrocarbons (PAH) in order to assess the effect of photolytic pretreatment on the subsequent fate of BaP in sewage sludge and soil test systems. Photolysis was performed in methanolic solution with or without 0.1 M H2O2, under either UV light (300 nm) or natural ...
R M, Miller, G M, Singer, J D, Rosen, R, Bartha   +3 more
openaire   +2 more sources

Bioremediation and microbial metabolism of benzo(a)pyrene [PDF]

Molecular Microbiology, 2018
SummaryThe growing release of organic contaminants into the environment due to industrial processes has inevitably increased the incidence of their exposure to humans which often results in negative health effects. Microorganisms are also increasingly exposed to the pollutants, yet their diverse metabolic capabilities enable them to survive toxic ...
Erin M, Ostrem Loss, Jae-Hyuk, Yu
openaire   +2 more sources

Cobinamide, a Vitamin B₁₂ Analog, Attenuates Benzo[a]pyrene and Pyrene Toxicity Through Selective Redox Modulation. [PDF]

Toxics
Kalyanaraman A, Stauffer CB, Gao W, Zhong T, Nguyen A, Casteel DE, Pilz RB, Boss GR, Kalyanaraman H, Tat J.   +9 more
europepmc   +1 more source

Benzo[a]pyrene exposure affect the formation of dental hard tissue via the regulation of glycerophospholipid metabolism. [PDF]

BMC Oral Health
Pan Y, Yu S, Feng X, Zhao Y, Cui D, Wang X.   +5 more
europepmc   +1 more source