Results 151 to 160 of about 79,764 (263)

Synaptic correlates of benzodiazepine tolerance. [PDF]

Mol Psychiatry
Piot A, Jovanovic JN.
europepmc   +1 more source

De‐Implementing Low‐Value Care in Dentistry: The Case for Choosing Wisely Campaigns

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT De‐implementation refers to the practice within implementation science that targets reducing low‐value care; that is practices that have been proven to be outdated, unnecessary, potentially harmful and in some cases not cost‐efficient. Reducing and removing habitual practices, as well as introducing new care, is not easy, as there are multiple
Fabio Arriola‐Pacheco, Rafael Aiello Bomfim, Karen Born, Herenia P. Lawrence   +3 more
wiley   +1 more source

Distinct clinical clusters of paediatric patients with status epilepticus: Retrospective cohort study

Developmental Medicine &Child Neurology, EarlyView.
Large Swiss cohort of paediatric status epilepticus demonstrates that treatment delay (> 60 min) directly contributes to morbidity. Machine‐learning analysis of routine clinical data identifies three distinct patient clusters: febrile status epilepticus, severe para‐infectious status epilepticus, and status epilepticus in children with known epilepsy ...
Richard J Burman, Anne Steinberg, Jamie Norris, Giorgio Selmin, Tommaso Fedele, Richard E Rosch, Georgia Ramantani   +6 more
wiley   +1 more source

ASO Author Reflections: Double Jeopardy-Risks of Opioid-Benzodiazepine Co-prescription in Older Adults with Gastrointestinal Cancer. [PDF]

Ann Surg Oncol
Mevawalla A, Pawlik TM.
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists and Incident Major Adverse Liver Outcomes in People With Type 2 Diabetes and Metabolic Dysfunction‐Associated Steatotic Liver Disease

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Treatment options for metabolic dysfunction‐associated steatotic liver disease (MASLD) are limited. While glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) and sodium‐glucose cotransporter‐2 (SGLT‐2) inhibitors improve cardiovascular outcomes, comparative effectiveness on liver‐related outcomes remains unclear.
Gregor A. Maier, Ramon A. Hofmann, Michael Roden, Wolfgang Rathmann, Oliver Kuss   +4 more
wiley   +1 more source

Context-Dependent Temporal Changes in Hypnotics Involved in Suicide Attempts. [PDF]

Neuropsychopharmacol Rep
Sasaki T, Sugawara N, Furukawa M, Iwaki H, Suda S, Yasui-Furukori N.   +5 more
europepmc   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

A population-based study exploring racial and gender inequities in polysubstance-related deaths across the United States from 2004 to 2022. [PDF]

Addiction
Cadet K, Brinzo P, Martins SS.
europepmc   +1 more source

A multidisciplinary, AI‐supported quality improvement intervention to manage polypharmacy in aging people with HIV

HIV Medicine, EarlyView.
Abstract Objectives Aging people with HIV are increasingly affected by multimorbidity and polypharmacy, which heighten the risk of drug–drug interactions (DDIs) and potentially inappropriate medications (PIMs). This study evaluated a multidisciplinary, AI‐supported quality improvement intervention designed to optimize polypharmacy management in older ...
Jovana Milic, Antonia Pugliese, Michela Belli, Gian Luca Lonardi, Caterina Ruffilli, Tommaso Albano, Marco Visicaro, Martina Ricciardetto, Pierluigi De Cosmo, Chiara Mussi, Francesca Gandolfi, Cristina Mussini, Costantino Grana, Giovanni Guaraldi   +13 more
wiley   +1 more source

Flumazenil reversal of remimazolam-induced sedation: a narrative review of safety, pharmacokinetics, and clinical considerations. [PDF]

Front Med (Lausanne)
Zhou Y, Wu W, Zhang Y, Peng Y, Jiang W, Zhang X, Ju F, Xie A.   +7 more
europepmc   +1 more source