Results 191 to 200 of about 131,739 (305)

Comparative effectiveness, safety and acceptability of pharmacological and psychosocial interventions for the treatment of cannabis use disorder: A network meta‐analysis

Addiction, EarlyView.
Abstract Aim Our primary aim was to conduct a network meta‐analysis (NMA) for the effectiveness, safety and acceptability of all psychosocial interventions and all pharmacotherapies for cannabis use disorder (CUD). Methods We conducted a NMA of studies identified from two completed systematic reviews examining the effectiveness, safety and ...
Monika Halicka, Francesca Spiga, Tom P. Freeman, Suzanne Nielsen, Jelena Savović, Julian P. T. Higgins, Deborah M. Caldwell   +6 more
wiley   +1 more source

The Emergence of Novel Benzodiazepines in Australia, Evidence, Alerts, Clinical Management and Harm Reduction-A Narrative Review. [PDF]

Drug Alcohol Rev
Freestone J, Kypri S, Schumann JL, Franklin E, Francis C, Barratt MJ, Peacock A, Sutherland R, Clifford B, MacDonald H, Ezard N, Fletcher K, Acheson L, Siefried KJ.   +13 more
europepmc   +1 more source

The Opioid Safety Toolkit: An interactive prescription opioid safety toolkit to increase opioid safety literacy and behaviours among people prescribed opioids for pain—a randomised controlled trial

Addiction, EarlyView.
Abstract Background and aims Prescription opioid‐related harm remains a significant public health concern. This study aimed to evaluate the efficacy of the Opioid Safety Toolkit, a co‐designed, interactive online resource, in increasing naloxone uptake and healthcare provider discussions among adults prescribed opioids for pain.
Suzanne Nielsen, Frederick Fox, Tina Lam, Alex Waddell, Monica Jung, Bosco Rowland, Jessica Watterson, Dhruv Basur, Chris Prawira, Joshua Paolo Seguin, Patrick Olivier, Jarrod McMaugh, Paul Dietze, Louisa Picco   +13 more
wiley   +1 more source

In vitro γ-aminobutyric acid A (GABA_A) receptor activity and binding interactions at the α⁺/γ₂^- interface of 53 prescription and designer benzodiazepines. [PDF]

Commun Chem
Norman C, Liin SI, Jauregi-Miguel A, Ottosson NE, Gréen H.   +4 more
europepmc   +1 more source

Drug sellers' use of a drug checking service amid the overdose crisis in British Columbia, Canada

Addiction, EarlyView.
Abstract Aims This study examined the use of a drug checking service by drug sellers in British Columbia, Canada, to assess motivations for service use and substances intended for distribution, focusing on risks associated with an unstable illicit drug market.
Pablo Gonzalez‐Nieto, Bruce Wallace, Collin Kielty, Irene Shkolnikov, Ava Margolese, Jaime Arredondo Sanchez Lira, Chris Gill, Dennis Hore   +7 more
wiley   +1 more source

Intranasal Diazepam Outperforms Midazolam and Lorazepam in Early Seizure Control in Pilocarpine-Induced Mice Model. [PDF]

Neurochem Res
Tong AH, Zhao J, Li J, Ban W, Wang RJ, Xie Y, Zhang Y, Zuo Z.   +7 more
europepmc   +1 more source

The feasibility of mindfulness‐based relapse prevention for adults with substance use disorders (illicit drugs) in a Chinese population: A pilot randomized controlled trial

Addiction, EarlyView.
Abstract Background and aims Mindfulness‐based relapse prevention (MBRP) has been shown to be beneficial to individuals with substance use disorder (SUD) in the West. The current pilot study aimed at testing the feasibility of MBRP in a Chinese population.
Ka Tsun Ting, Ivan Chun Him Leung, Dicken Cheong Chun Chan, Ken On Tai Yu, Wai Kwong Tang, Fu Chan, Alan Ka Lam Tang, Helen Shuk Wah Ma, Benjamin Hon Kei Yip, Daisy Dexing Zhang, Sarah Bowen, Samuel Yeung Shan Wong   +11 more
wiley   +1 more source

Unintentional benzodiazepine use and frequency of drug checking service utilization: a cross-sectional study. [PDF]

Harm Reduct J
Airth L, Goodyear T, Marshall BDL, Grant C, Lysyshyn M, Sherman SG, Wood E, Ti L.   +7 more
europepmc   +1 more source

Context, mechanisms and outcomes of a social enterprise model of residential rehabilitation for problem substance use: A realist‐informed process evaluation

Addiction, EarlyView.
Abstract Background and aims This study evaluated a three‐year residential rehabilitation programme, which aimed to support recovery from problem substance use via peer support and social enterprise activities. The aims were to clarify programme mechanisms and identify contextual factors associated with variation in outcomes.
Martin Anderson, Lucy Pickering, Mark McCann   +2 more
wiley   +1 more source

Association between gabapentinoid treatment, concurrent use with opioid or benzodiazepine and the risk of drug poisoning: A self-controlled case series study. [PDF]

PLoS Med
Yuen ASC, Chen B, Chan AYL, Hayes JF, Osborn DPJ, Besag FMC, Lau WCY, Wong ICK, Wei L, Man KKC.   +9 more
europepmc   +1 more source