Lemborexant 10 mg, a dual orexin‐receptor antagonist (DORA), did not elicit respiratory depressant effects, as measured by peripheral oxygen saturation (SpO2) or apnea–hypopnea index (AHI), in subjects with moderate‐to‐severe chronic obstructive pulmonary disease (COPD).
Jocelyn Y. Cheng +3 more
wiley +1 more source
Benzodiazepine-related polysubstance use and hospital resource utilization in older trauma patients: a retrospective multicenter study. [PDF]
McGraw C +6 more
europepmc +1 more source
ABSTRACT Treating obstructive sleep apnea (OSA) has been shown to improve concomitant insomnia symptoms, but whether treating OSA translates into reducing sedative medication use is unknown. We evaluated the association between initiating incident positive airway pressure (PAP) therapy and continued benzodiazepine drug receipt among chronic ...
Nicholas T. Vozoris +3 more
wiley +1 more source
Management algorithm for alcohol withdrawal syndrome, alcohol dependence (AD) and AD with anxiety in the Indian population: a narrative review with expert opinion. [PDF]
Kumar MS, Vaishnav M, Saha G, Raheja D.
europepmc +1 more source
ABSTRACT Sleep is increasingly understood as a socially embedded phenomenon. This study examined how structural and functional aspects of social support, as well as loneliness, relate to sleep health in a German sample of middle‐aged adults (N = 5388).
Eva De Camargo +9 more
wiley +1 more source
Benzodiazepine receptor agonists in hospitalised patients in the Netherlands: initiation, continuation and discontinuation - a retrospective observational analysis. [PDF]
de Gans CJ +6 more
europepmc +1 more source
ABSTRACT Slow‐wave sleep (SWS; stage N3) is often reported as reduced in depression, yet variability across depressive phenotypes remains poorly characterised. This study aimed to determine whether N3 architecture—proportion, duration, and latency—identifies clinically distinct profiles in major depressive episode (MDE).
Antoine Salmeron +8 more
wiley +1 more source
Challenges in the End-of-Life Care for Patients With Severe Persistent Mental Illness: A Case Series. [PDF]
Jayakody K, Bajaj I, Blomeley D.
europepmc +1 more source
Post‐ICU Psychotropic Medication Initiation in Nonagenarian Sepsis Survivors
Journal of the American Geriatrics Society, EarlyView.
Yuichiro Shimoyama +2 more
wiley +1 more source
Trends in Sedative-Hypnotic Prescription Among Insomnia Patients: A Nationwide Cohort Study From 2010 to 2022 in Korea. [PDF]
Shin J +8 more
europepmc +1 more source

