Results 141 to 150 of about 17,221 (205)
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Benzofuran derivatives. Part 3 On the reactivities of the intermediates in benzofuran synthesis
Journal of Heterocyclic Chemistry, 1987Abstract3‐Methyl‐5‐nitrobenzofuran (2) and 3‐methyl‐5‐nitrobenzofuran‐2‐carboxylic acid (3) were obtained by heating 2‐acetyl‐4‐nitrophenoxyacetic acid (1) with various bases in acetic anhydride. It appeared that 3‐hydroxy‐3‐methyl‐5‐nitro‐2,3‐dihydrobenzofuran‐2‐carboxylic acid (4) was the intermediate in the benzofuran synthesis.
Takaaki Horaguchi +3 more
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Bioactive Benzofuran derivatives: A review
European Journal of Medicinal Chemistry, 2015In nature's collection of biologically active heterocycles, benzofuran derivatives constitute a major group. The broad spectrum of pharmacological activity in individual benzofurans indicates that this series of compounds is of an undoubted interest.
Hena, Khanam, , Shamsuzzaman
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Benzofuran based PDE4 inhibitors
Bioorganic & Medicinal Chemistry, 1999Replacement of the 3,4-dialkoxyphenyl substructure common to a number of PDE4 inhibitors with a 2-alkyl-7-methoxybenzofuran unit is described. This substitution can result in either enhancement or substantial reductions in PDE4 inhibitory activity depending on the system to which it is applied.
D G, McGarry +9 more
openaire +2 more sources
2012
This chapter reviews the significant developments in the metalation of furans and benzofurans and applications of the resulting metalated species in the past decade. New and interesting metalated furan and benzofuran derivatives and their novel reactions are featured.
openaire +1 more source
This chapter reviews the significant developments in the metalation of furans and benzofurans and applications of the resulting metalated species in the past decade. New and interesting metalated furan and benzofuran derivatives and their novel reactions are featured.
openaire +1 more source
Structure–Activity Relationship of Benzofuran Derivatives with Potential Anticancer Activity
Cancers, 2022Basem Al-Omari +2 more
exaly
Remarks on Synthesis of Benzofurans
Journal of Pharmaceutical Sciences, 1968openaire +2 more sources

