Results 31 to 40 of about 30,744 (240)
Investigation of furo[2,3-h]- and pyridazino[3,4-f]cinnolin-3-ol scaffolds as substrates for the development of novel HIV-1 integrase inhibitors [PDF]
, 2011 With the aim to develop novel HIV-1 integrase inhibitors, we obtained a set of condensed ring systems based on the furo[2,3-h]cinnolin-3(2H)-one and pyridazino[3,4-f]cinnolin-3-ol scaffolds bearing a potential chelating pharmacophore, which can be ...
Casule, Paola +7 more
core +1 more source
Angewandte Chemie, EarlyView.A Pd‐catalyzed regioselective synthesis of benzylsilanols from Kobayashi‐type reagents has been developed through a mechanistically distinct approach involving 1,4‐Pd migration followed by intramolecular transmetalation. The reaction can be combined with various prior transition‐metal‐catalyzed processes and the resulting benzylsilanols have been ...
Ryo Shintani, Keisuke Tachibana
wiley +2 more sources
2-Arylbenzofuran Neolignans from the Bark of (Lauraceae)
Natural Product Communications, 2010 The toluene extract of the stem bark of N. purpurascens (R&P) Mez. contained a large amount of these 2-arylbenzofurans including methyl 7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran-5-carboxylate ( 2 ), a new benzofuran, along with three known ...
Jaime Rios-Motta, Eliseo Avella
doaj +1 more source
2-Methyl-5,6-methylenedioxy-3-phenylsulfonyl-1-benzofuran
Acta Crystallographica Section E, 2008 The title compound, C16H12O5S, was prepared by oxidation of 2-methyl-5,6-methylenedioxy-3-phenylsulfanyl-1-benzofuran with 3-chloroperoxybenzoic acid.
Uk Lee +3 more
doaj +1 more source
Angewandte Chemie, EarlyView.The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans +3 more
wiley +2 more sources
5-Fluoro-2-(4-iodophenyl)-3-methylsulfinyl-1-benzofuran
Acta Crystallographica Section E, 2009 In the title compound, C15H10FIO2S, the O atom and the methyl group of the methylsulfinyl substituent lie on opposite sides of the plane through the benzofuran fragment.
Hong Dae Choi +3 more
doaj +1 more source
A Computational Modeling of ADLumin Chemiluminescence: Oxygenation and Dioxetanone Formation. [PDF]
J Comput ChemChemiluminescent ADLumin molecules were studied using DFT to investigate their mechanisms of oxygenation and dioxetanone formation. Different oxygenation sites were explored for initiating competing reaction pathways that converge to the same 1,2‐dioxetanone intermediate.
Wickizer C +5 more
europepmc +2 more sources
Synthesis of aza-rocaglates via ESIPT-mediated (3+2) photocycloaddition [PDF]
, 2016 Synthesis of aza-rocaglates, nitrogen-containing analogues of the rocaglate natural products, is reported. The route features ESIPT-mediated (3+2) photocycloaddition of 1-alkyl-2-aryl-3-hydroxyquinolinones with the dipolarophile methyl cinnamate.
Cencic, Regina +4 more
core +1 more source
2-(4-Fluorophenyl)-3-methylsulfanyl-5-phenyl-1-benzofuran
Acta Crystallographica Section E, 2009 In the title compound, C21H15FOS, the 4-fluorophenyl ring is rotated out of the benzofuran plane, making a dihedral angle of 24.3 (1)°. The dihedral angle between the phenyl ring and the benzofuran plane is 28.3 (1)°.
Hong Dae Choi +3 more
doaj +1 more source
2-(2-Methoxyphenyl)-1-benzofuran [PDF]
Acta Crystallographica Section E Structure Reports Online, 2011 In the title compound, C(15)H(12)O(2), the dihedral angle between the aromatic ring systems is 16.67 (6)°. The methyl C atom is almost coplanar with its attached benzene ring [displacement = 0.020 (2) Å]. In the crystal, the mol-ecules are connected by weak C-H⋯O bonds and face-to-edge C-H⋯π inter-actions between the 2-meth-oxy-phenyl rings.
Michaela Pojarová +4 more
openaire +3 more sources