Results 21 to 30 of about 21,297 (236)
, 2020 Pursuing our effort for developing effective inhibitors of the cancer-related hCA IX isoform, here we describe the synthesis of novel benzofuran-based carboxylic acid derivatives, featuring the benzoic (9a–f) or hippuric (11a,b) acid moieties linked to 2-
Nada Aljaeed (8604156) +8 more
core +1 more source
Molecules, 2022 Bone morphogenetic proteins (BMPs) are growth factors that have a vital role in the production of bone, cartilage, ligaments, and tendons. Tumors’ upregulation of bone morphogenetic proteins (BMPs) and their receptors are key features of cancer ...
Amany Belal +9 more
doaj +1 more source
2-(4-Bromophenyl)-5-fluoro-3-methylsulfinyl-1-benzofuran
Acta Crystallographica Section E, 2009 In the title compound, C15H10BrFO2S, the O atom and the methyl group of the methylsulfinyl substituent lie on opposite sides of the plane through the benzofuran fragment.
Hong Dae Choi +3 more
doaj +1 more source
Synthesis of Novel Ferrocene-Benzofuran Hybrids via Palladium- and Copper-Catalyzed Reactions
Inorganics, 2022 The combination of the ferrocene skeleton with pharmacophores often leads to molecules with interesting biological properties. Five ferrocene-benzofuran hybrids of different structures were synthesized by transition metal catalyzed reactions.
Enikő Nagy +9 more
doaj +1 more source
5-Bromo-2-methyl-3-phenylsulfonyl-1-benzofuran
Acta Crystallographica Section E, 2008 The title compound, C15H11BrO3S, was prepared by the oxidation of 5-bromo-2-methyl-3-phenylsulfanyl-1-benzofuran with 3-chloroperoxybenzoic acid. The phenyl ring makes a dihedral angle of 78.99 (8)° with the plane of the benzofuran fragment ...
Uk Lee +3 more
doaj +1 more source
2,5,7-Trimethyl-3-phenylsulfinyl-1-benzofuran
Acta Crystallographica Section E, 2008 The title compound, C17H16O2S, was prepared by the oxidation of 2,5,7-trimethyl-3-phenylsulfanyl-1-benzofuran with 3-chloroperoxybenzoic acid. The O atom and the phenyl group of the phenylsulfinyl substituent lie on opposite sides of the plane of the ...
Hong Dae Choi +3 more
doaj +1 more source
Catalytic Functionalization of Unactivated π‐Bonds Enabled by Bidentate Directing Auxiliaries
Angewandte Chemie, EarlyView.This review explores how bidentate directing auxiliaries have advanced transition‐metal catalysis for unactivated alkene/alkyne functionalization. By leveraging chelated intermediates, bidentate directing auxiliaries enable precise hydrofunctionalization, difunctionalization, and C─H activation of π‐bonds with unique selectivity and reactivity.
Seunghyeon Cho +4 more
wiley +2 more sources
Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
Green Processing and Synthesis, 2017 A highly efficient, eco-friendly and one-pot synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles was developed involving the reaction of 2-acetyl benzofurans and 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole in the presence of molecular ...
Kumar Surender, Sharma Dinesh Kumar
doaj +1 more source
Transition Metal‐Free Heteroarene Insertion Into C─C Bonds of Benzocyclobutenones
Angewandte Chemie, EarlyView.A transition metal‐free insertion of five‐membered heteroarenes into the C─C bonds of benzocyclobutenones has been achieved under mild and operationally simple conditions. This method provides an efficient and modular approach to access fused partially saturated hetero‐polycyclic scaffolds that exist in many bioactive molecules.
Cole J. Wagner, Guangbin Dong
wiley +2 more sources
2-Arylbenzofuran Neolignans from the Bark of (Lauraceae)
Natural Product Communications, 2010 The toluene extract of the stem bark of N. purpurascens (R&P) Mez. contained a large amount of these 2-arylbenzofurans including methyl 7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran-5-carboxylate ( 2 ), a new benzofuran, along with three known ...
Jaime Rios-Motta, Eliseo Avella
doaj +1 more source