Results 161 to 170 of about 55,719 (254)

Knocking Out Two Polyphenol Oxidase Genes Significantly Improves Recombinant Protein Purification in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Efficient purification remains a key technical challenge affecting the recovery efficiency of recombinant proteins in plant‐based systems. Complex metabolites, particularly polyphenols, often cause recombinant protein aggregation during purification.
Hai‐Ping Diao   +7 more
wiley   +1 more source

The Structure of Carboxyl Methyltransferase Provides Insights Into the Substrate Specificity and Divergent Evolution of Iridoid

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Iridoids constitute a prominent class of plant‐specialised metabolites, with carbocyclic iridoids (e.g., geniposide) and secoiridoids (e.g., loganin) diverging early in their biosynthetic pathways. This divergence is marked by substrate‐specific carboxyl methyltransferases—GjGAMT and CrLAMT—that catalyse the decisive methylation step in ...
Li Li   +7 more
wiley   +1 more source

Virocell Necromass Provides Limited Plant Nitrogen and Elicits Rhizosphere Metabolites That Affect Phage Dynamics

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Bacteriophages impact soil bacteria through lysis, altering the availability of organic carbon and plant nutrients. However, the magnitude of nutrient uptake by plants from lysed bacteria remains unknown, partly because this process is challenging to investigate in the field.
Vlastimil Novak   +10 more
wiley   +1 more source

Multi‐Omics Analyses Reveal the Red and Far‐Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang   +6 more
wiley   +1 more source

Prevention of Atopic Dermatitis in High‐Risk Infants: A Review of the Role of Lipid‐Based Barrier Repair Therapy

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Background/Objective Growing evidence highlights the role of physiological lipids, namely ceramides, cholesterol, and free fatty acids, in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid‐based therapies to prevent AD and ...
Chon‐Wai Jeremy Chan   +1 more
wiley   +1 more source

Structure-Guided Discovery of Benzoic-Acid-Based TRPC6 Ligands: An Integrated Docking, MD, and MM-GBSA SAR Study: Potential Therapeutic Molecules for Autism Spectrum Disorder. [PDF]

open access: yesPharmaceuticals (Basel)
Silva NI   +10 more
europepmc   +1 more source

Immobilized CuCl2/TiO2 photocatalysts for the selective oxidation of benzyl alcohol to benzaldehyde

open access: yesPhotochemistry and Photobiology, EarlyView.
The photocatalytic aerobic oxidation of benzyl alcohol to benzaldehyde was investigated using free and alginate‐immobilized CuCl2 and/or TiO2 (P25) catalysts under UV irradiation. Immobilization enabled catalyst recovery and maintained high benzaldehyde selectivity but led to reduced activity due to internal oxygen diffusion limitations, which were ...
Nosaibeh Nosrati‐Ghods   +3 more
wiley   +1 more source

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