Results 191 to 200 of about 128,406 (294)

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

open access: yesThe FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek   +12 more
wiley   +1 more source

Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3

open access: yesThe FEBS Journal, EarlyView.
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova   +6 more
wiley   +1 more source

Improved Syntheses, Crystal Structures Analysis, DFT Calculation, Anticancer and Antibacterial Properties of Some 4‑(Benzylamino)benzoic Acid Derivatives. [PDF]

open access: yesACS Omega
Hijazi AK   +9 more
europepmc   +1 more source

Erosion Potential of Commercial Fluoride‐Free Mouthwashes on Dental Hard Tissues

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Purpose Mouthwashes often present acidic pH, which raises concerns about their potential contribution to erosive tooth wear. This study evaluated the erosive potential of commercial fluoride‐free mouthwashes using a screening method.
Astrid C. Valdivia‐Tapia   +5 more
wiley   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis   +2 more
wiley   +1 more source

Synthesis, In Silico, and Biological Evaluation of Non-Hydroxamate Benzoic Acid-Based Derivatives as Potential Histone Deacetylase Inhibitors (HDACi). [PDF]

open access: yesChem Biodivers
Al Rahim NAA   +8 more
europepmc   +1 more source

A Narrative Review of Candidate Biomarkers of Total Fruit and Vegetable Intake

open access: yesNutrition Bulletin, EarlyView.
ABSTRACT While an abundance of cohort studies has suggested that greater consumption of fruits and vegetables (FVs) is associated with reduced risk of chronic diseases, current self‐report based dietary assessment tools are susceptible to biases that can reduce their accuracy in estimating dietary intakes, and consequently, the risk estimates obtained ...
Matthew P. Madore   +7 more
wiley   +1 more source

Surface Defects and Crystal Growth of Apremilast Benzoic Acid Cocrystals. [PDF]

open access: yesOrg Process Res Dev
Jirát J   +3 more
europepmc   +1 more source

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