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[Tolerance to benzonidazole during the etiological treatment of Chagas' disease].
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Eritema polimorfo devido ao Benzonidazol, no tratamento da doença de Chagas
Amato Neto, Vicente +2 more
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Avaliação de possíveis alterações teciduais de camundongas prenhas infectadas oralmente por Trypanosoma cruzi e tratadas com benzonidazol [PDF]
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Parasite Immunology, 2023
Abstract Benznidazole (Bz) is the recommended drug for the treatment of Chagas disease; however, its efficacy may vary according to the sensitivity of Trypanosoma cruzi strains to the drug and host immune background.
Leyllane Rafael Moreira +11 more
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Abstract Benznidazole (Bz) is the recommended drug for the treatment of Chagas disease; however, its efficacy may vary according to the sensitivity of Trypanosoma cruzi strains to the drug and host immune background.
Leyllane Rafael Moreira +11 more
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International Journal of Cardiology, 2010
Chronic chagasic cardiac patients are exposed to oxidative stress that apparently contributes to disease progression. Benznidazole (BZN) is the main drug used for the treatment of chagasic patients and its action involves the generation of reactive species.
Carine Muniz, Ribeiro +9 more
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Chronic chagasic cardiac patients are exposed to oxidative stress that apparently contributes to disease progression. Benznidazole (BZN) is the main drug used for the treatment of chagasic patients and its action involves the generation of reactive species.
Carine Muniz, Ribeiro +9 more
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Mitochondrial Bioenergetics after Nine-Day Treatment Regimen with Benzonidazole in Rats
International Journal of Toxicology, 2007The bioenergetics of cardiac, liver, and kidney mitochondria after 9-day treatment regimen with benzonidazole was studied in rats. The drug was given by oral gavage to adult male Sprague-Dawley rats for 9 consecutive days (100 mg benzonidazole/kg body weight as daily dose).
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Cellular and humoral immune response in human Chagas’ disease after treatment with Benzonidazol
The Journal of Immunology, 2016Abstract Chagas’ disease (caused by Trypanosoma cruzi) remains a leading neglected tropical disease in the Americas, associated with 546,000 disability adjusted life years and 10,300 annual deaths. Even today there is a lack of studies proving the effectiveness and effects of treatment with benznidazole in chronic patients, as well as ...
Virmondes Rodrigues +3 more
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[Benzonidazole: one of the rare treatment for Chagas disease].
Medecine tropicale : revue du Corps de sante colonial, 2011Benznidazole is indicated in the treatment of Chagas' disease, which is endemic in Latin America. However, it has numerous adverse effects and is effective only at certain disease stages. Because of these drawbacks and the appearance of resistance to benzinidazole, there is ongoing research for alternative therapeutic strategies and new drugs.
C, Coilliot +6 more
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ARACÊ
A doença Chagas (DC) possui uma maior prevalência em países que estão localizados em regiões tropicais e úmidas. A doença ainda segue como um problema de saúde pública em diversas regiões do mundo, principalmente em áreas endêmicas como observado em vários países sul-americanos. O tratamento medicamentoso na fase aguda da doença é eficiente, mas possui
Yasmin de Castro Vieira +8 more
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A doença Chagas (DC) possui uma maior prevalência em países que estão localizados em regiões tropicais e úmidas. A doença ainda segue como um problema de saúde pública em diversas regiões do mundo, principalmente em áreas endêmicas como observado em vários países sul-americanos. O tratamento medicamentoso na fase aguda da doença é eficiente, mas possui
Yasmin de Castro Vieira +8 more
openaire +1 more source

