Results 11 to 20 of about 3,127 (182)
Medicines, 2023 Background. Many anti-cancer drugs used in clinical practice cause adverse events such as oral mucositis, neurotoxicity, and extravascular leakage. We have reported that two 3-styrylchromone derivatives, 7-methoxy-3-[(1E)-2-phenylethenyl]-4H-1-benzopyran-
Tomoyuki Abe +14 more
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Molecules, 2010 During a synthesis of coumarins to obtain new candidates for treating Alzheimer’s Disease (AD), an unusual rearrangement of a benzopyran group to a benzofuran group occurred, offering a novel synthesis pathway of these benzofuran derivatives.
Ling-Yi Kong +4 more
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Orbital: The Electronic Journal of Chemistry, 2014 Novel substituted benzopyran-2-one derivatives were synthesized by catalytic condensation reactions under reflux conditions. 4-(1,2,4-Triazolyl-3-amino)-3-nitro-2H-[1]-benzopyran-2-ones 4(a-b) were synthesized by condensation of 4-chloro-3-nitro-2H-[1 ...
Ramiz Hoti +6 more
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Marine Drugs, 2016 Two new pentaketides, including a new benzofuran-1-one derivative (1) and a new isochromen-1-one (5), and seven new benzoic acid derivatives, including two new benzopyran derivatives (2a, b), a new benzoxepine derivative (3), two new chromen-4-one ...
Chadaporn Prompanya +7 more
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Solid-Phase Parallel Synthesis of Drug-Like Artificial 2<em>H</em>-Benzopyran Libraries
Molecules, 2012 This review covers the construction of drug-like 2<em>H</em>-benzopyrans and related libraries using solid-phase parallel synthesis. In this context, the preparation of substituted benzopyrans such as mono-, di- and trisubstituted benzopyran ...
Young-Dae Gong, Taeho Lee
doaj +1 more source
Effects of Structural Manipulation on the Bioactivity of some Coumarin-Based Products [PDF]
Archives of Razi Institute, 2021 Coumarin (2H-1-benzopyran-2-one) is a plant-derived natural product known for its pharmacological properties, such as anti-inflammatory, anticoagulant, antibacterial, antifungal, antiviral, anticancer, antihypertensive, antitubercular, anticonvulsant ...
Y Fakri Mustafa +4 more
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Synthesis, Photophysical Characterization, and Anticancer Evaluation of Novel Furochromene Derivatives. [PDF]
ChemistryOpenThis is the first study on novel furochromene derivatives. A series of novel furochromen derivatives, namely (2E)‐1‐(6‐hydroxy‐4,7‐dimethoxy‐1‐benzofuran‐5‐yl)‐3‐arylprop‐2‐en‐1‐ones 4a–c, were synthesized via the Knoevenagel condensation of 6‐hydroxy‐4,7‐dimethoxybenzofuran‐5‐ylethanone 2 with various aromatic aldehydes.
Rabahi A +9 more
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Synthesis and Antimicrobial Activities of Some Sulphur Containing Chromene Derivatives
Natural Product Communications, 2012 A series of 3,3-dimethyl-3 H benzothieno[3,2- f ][1]-benzopyran analogues modified at the pyran 1,2-double bond were synthesized. The corresponding dihydro and (±)-cis-diol derivatives were converted into diacetate and cyclic carbonate upon acylation ...
Tuba Şerbetçi +4 more
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Molecules, 2012 The in vitro antioxidant activities of eight 3-carboxycoumarin derivatives were assayed by the quantitative 1,1-diphenyl-2-picrylhydrazil (DPPH•) radical scavenging activity method.
Maria Teresa Sumaya-Martínez +6 more
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Characterization of the xiamenmycin biosynthesis gene cluster in Streptomyces xiamenensis 318.
PLoS ONE, 2014 Xiamenmycin (1) is a prenylated benzopyran derivative with anti-fibrotic activity. To investigate the genetic basis of xiamenmycin biosynthesis, we performed genome mining in the xiamenmycin-producing Streptomyces xiamenensis wild-type strain 318 to ...
Yong Yang +5 more
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