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Biotransformation of Coumarins: Mechanisms and Pharmaceutical Potential [PDF]
MoleculesCoumarins are compounds that are naturally found in various plants and are known for their potential pharmacological characteristics, such as anti-inflammatory, antibacterial, antiparasitic, and anticoagulant activities.
Mutiara Saragih +2 more
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PharmaceuticsCoumarins are natural organic compounds widely found in plants that show promising anticancer properties. This article reviews the current research on the mechanisms of action of coumarins in cancer therapy, including the induction of apoptosis ...
David Aebisher, Tomasz Kubrak
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Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials [PDF]
المجلة العراقية للصيدلة, 2022 Background: Natural coumarins group, a principal member of the benzopyrone family, is one of the naturally occurring substances obtained ordinarily from plant origins, with antibacterial, anticoagulant, antihypertensive, anticancer, antioxidant, anti ...
Rahma Jebir, Yasser Mustafa
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Coumarin-based products: Their biodiversity and pharmacology [PDF]
المجلة العراقية للصيدلة, 2022 Background: The plant kingdom generates and releases a wide range of secondary-metabolites, which have several effects on biological, toxicological, and ecological systems that may act in a similar manner to chemically synthesized compounds. One of these
Reem Ismael +2 more
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Coumarins as Fungal Metabolites with Potential Medicinal Properties
Antibiotics, 2022 Coumarins are a structurally varied set of 2H-chromen-2-one compounds categorized also as members of the benzopyrone group of secondary metabolites. Coumarin derivatives attract interest owing to their wide practical application and the unique reactivity
Olga M. Tsivileva +2 more
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Coumarins of genus Ferula L. (Apiaceae Lindl.)
Eurasian Chemico-Technological Journal, 2023 The biologically active coumarins from Ferula L. species of the family Apiaceae Lindl. for the period 1970 to 2022 have been reviewed. The phytochemical investigation of different parts of Ferula L., including gum resin, leaves, fruits, seeds, roots ...
T.S. Khosnutdinova +3 more
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Nature, 1966 BY sorption on ion exchange resins1–3 it is possible to separate some coumarins in dilute solution. A column of the strongly basic anion exchange resin, ‘Amberlite IRA–400’ (−40, +60 mesh; Rohm and Haas Co.), in the chloride form (bed length, 50 cm; bed volume, 25.8 c.c.) has been used for this purpose.
D J, Patel, S L, Bafna
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Coumarins and Coumarin-Related Compounds in Pharmacotherapy of Cancer [PDF]
Cancers, 2020 Cancer is one of the most common causes of disease-related deaths worldwide. Despite the discovery of many chemotherapeutic drugs that inhibit uncontrolled cell division processes for the treatment of various cancers, serious side effects of these drugs are a crucial disadvantage.
Esra Küpeli Akkol +4 more
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Coumarin derivatives as antifungal agents - A review
Czech Journal of Food Sciences, 2023 Coumarins and pyridines are a promising class of naturally occurring bioactive heterocycles with unique physical and chemical properties. Compounds containing the coumarin framework possess a wide range of pharmacological, biological, and physiological ...
Mirjana Lončar +2 more
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Molecules, 2020 In this study, eight coumarins (coumarins 1–8) are proposed as near-UV and blue light sensitive photoinitiators/photosensitizers for the cationic polymerization (CP) of epoxysilicones when combined with 4-isopropyl-4’-methyldiphenyliodonium tetrakis ...
Mira Abdallah +3 more
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