Results 21 to 30 of about 24,198 (212)

A Review on Anti-Tumor Mechanisms of Coumarins

Frontiers in Oncology, 2020
Coumarins are a class of compound with benzopyrone as their basic structure. Due to abundant sources, easy synthesis, and various pharmacological activities, coumarins have attracted extensive attention from researchers.
Yi Wu, Jing Xu, Yiting Liu, Yiyu Zeng, Guojun Wu   +4 more
doaj   +1 more source

3-Substituted Coumarins Inhibit NorA and MepA Efflux Pumps of Staphylococcus aureus

Antibiotics, 2023
Coumarins are compounds with scientifically proven antibacterial properties, and modifications to the chemical structure are known to improve their effects.
José B. de Araújo-Neto, Cícera D. de M. Oliveira-Tintino, Gildênia A. de Araújo, Daniel S. Alves, Fernanda R. Ribeiro, Guilherme A. Brancaglion, Diogo T. Carvalho, Clara Mariana Gonçalves Lima, Hani S. H. Mohammed Ali, Irfan A. Rather, Mohmmad Y. Wani, Talha B. Emran, Henrique D. M. Coutinho, Valdir de Q. Balbino, Saulo R. Tintino   +14 more
doaj   +1 more source

Structure–Activity Analysis and Molecular Docking Studies of Coumarins from Toddalia asiatica as Multifunctional Agents for Alzheimer’s Disease

Biomedicines, 2020
Coumarins, naturally occurring phytochemicals, display a wide spectrum of biological activities by acting on multiple targets. Herein, nine coumarins from the root of Toddalia asiatica were evaluated for activities related to pathogenesis of Alzheimer’s ...
Pitchayakarn Takomthong, Pornthip Waiwut, Chavi Yenjai, Bungon Sripanidkulchai, Prasert Reubroycharoen, Ren Lai, Peter Kamau, Chantana Boonyarat   +7 more
doaj   +1 more source

2-Oxoglutarate-dependent dioxygenases in the biosynthesis of simple coumarins

Frontiers in Plant Science, 2014
Coumarins are natural plant products that have been the subject of extensive phytochemical and pharmacological research studies in the past few decades.
Bun-Ichi eShimizu
doaj   +1 more source

Safety Profile of Nutraceuticals Rich in Coumarins: An Update

Frontiers in Pharmacology, 2022
Coumarins are a family of benzopyrones largely distributed in the natural kingdom, being present in the seeds, fruits, flowers, or roots of various plant species.
Simona Codruta Heghes, Oliviu Vostinaru, Cristina Mogosan, Doina Miere, Cristina Adela Iuga, Cristina Adela Iuga, Lorena Filip   +6 more
doaj   +1 more source

Auraptene Promotes THP-1 Polarization to M1 Macrophages and Improves M1 Function [PDF]

Research Journal of Pharmacognosy, 2022
Background and Objectives: Macrophages play an important role in tumor growth (M2 macrophage) or suppression (M1 macrophage). Auraptene, a prenyloxycoumarin compound extracted from Citrus plants, has anti-cancer and anti-inflammatory properties.
Afshin Jalali, Mostafa Haji Molla Hoseini, Mitra Rezaei, Seyed Ali Ziai*   +3 more
doaj   +1 more source

Antagonists of Vitamin K—Popular Coumarin Drugs and New Synthetic and Natural Coumarin Derivatives

Molecules, 2020
Many natural coumarins and their chemically synthesized analogs and derivatives exert diverse properties, such as anticancer, antioxidant, anti-inflammatory, or anticoagulant, with the latter being of the utmost importance.
Kinga Kasperkiewicz, Michał B. Ponczek, Jacek Owczarek, Piotr Guga, Elżbieta Budzisz   +4 more
doaj   +1 more source

Synthesis, complete assignment of 1H- and 13C-NMR spectra and antioxidant activity of new azine derivative bearing coumarin moiety [PDF]

Bulletin of Natural Sciences Research, 2021
In this research, the synthesis of a new azine derivative with coumarin moiety was performed in three reaction steps, starting from 4-hydroxycoumarin.
Ristić Milenko, Dekić Biljana, Radulović Niko, Aksić Marija   +3 more
doaj   +1 more source

Coumarins from

Natural Product Communications, 2010
Linear-type furocoumarins, 5-[(2″ E ,6″R)-6″-hydroxy-3″,7″-dimethylocta-2″,7″-dienyloxy]psoralen and 5-[(2″ E ,6″ S )-6″-hydroxy-3″,7″-dimethylocta-2″,7″-dienyloxy]psoralen ( 1 ) were first isolated from whole plants of Seseli hartvigii together with one
Lin Zhang, Alev Tosun, Masaki Baba, Yoshihito Okada, Lijun Wu, Toru Okuyama   +5 more
doaj   +1 more source

Comprehensive chemo-profiling of coumarins enriched extract derived from Aegle marmelos (L.) Correa fruit pulp, as an anti-diabetic and anti-inflammatory agent

Saudi Pharmaceutical Journal, 2023
Aegle marmelos (L.) Correa is an Indian medicinal plant known for its vast therapeutic activities. In Ayurveda, the plant is known to balance “vata,” “pitta,” and “kapha” dosh.
Ritu Tiwari, Smita Mishra, Gnanabhaskar Danaboina, Gaurav Pratap Singh Jadaun, M. Kalaivani, Vivekanandan Kalaiselvan, Mahaveer Dhobi, Rajeev S Raghuvanshi   +7 more
doaj   +1 more source